Protocol Review Committee

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Protocol Review Committee

The Protocol Review Committee (PRC) is charged with providing institutional peer review of all cancer-related clinical research protocols, except for trials that have received a previous peer review (e.g. NCI cooperative group trials.)

  • Reviewing scientific merit of clinical trials
  • Prioritization of competing protocols
  • Monitor protocol accrual for all studies within the cancer center


The PRC functions at a high level of efficiency through the Cancer Center Clinical Trials Management System, OnCore. All submissions and reviews occur within this system.  Documents required for PRC submission and review include:

  • Sponsor Protocol
  • IRB Protocol or Application
  • Investigator Brochure (if applicable)


Additional Resources:
IRB for Health Sciences Research