Jason P. Sheehan, MD, PhD
Axonal Guidance Cues
My research interests include the study of axonal guidance cues. Such cues are important for axonal regeneration and functional recovery following various types of neurological injury such as stroke, neurodegeneration, and trauma.
In addition, my research group is exploring the neuronal changes accompanying seizure attenuation after stereotactic radiosurgical lesioning of the mesial hippocampus. Interneuronal changes in the hippocampus following Gamma surgery are one of the alterations noted following subnecrotic doses of Gamma surgery to the hippocampus. Such underlying mechanisms may provide insight into the efficacy of Gamma Knife surgery for the treatment of temporal lobe epilepsy.
Both research interests are pursued through my affiliation with the neuroscience department.