MAPS Core services are billed in 15 minute increments of $90/hour on a monthly basis. Projects are scheduled on a first come first serve basis. PTAO provision is required to initiate services.
To ensure the highest probability that an experiment will be fully
informative, we offer consultation from our experienced staff and board
of technical and scientific experts in the design of animal experiments
from start to finish. Areas of consideration include cost estimation;
animal welfare committee (IACUC) and biosafety committee (BSL)
regulatory compliance; logistical detailing and planning;
biostatistics; specimen collection, storage and analysis; imaging and
molecular assessments. Please note: necessary regulatory approvals to
perform the studies must be obtained before studies can
The profile of animal research studies can range from short and
uncomplicated to intricate, time-consuming and lengthy. The MAPS Core
has the dedicated staff and expertise to initiate your study and
perform it to completion, however complicated or simple. Additionally
we can coordinate any necessary services in other UVA Shared Resources
facilities for you, thereby providing a single point of contact for a
PI to carry out an entire study that might include the culture of
cells, immunohistochemistry, flow cytometry, molecular analyses of
tumors, and statistics.
We prepare and administer single and combination therapeutics in
treatment regimens as well as maximum tolerated dose evaluations.
Therapeutics includes Small Molecules, Biopharmaceuticals, Vaccines,
Radio-sensitizers, Medical Devices, and Nanotechnology
We offer once and twice weekly animal monitoring in the forms of
animal weight checks, health assessments, tumor measurements, imaging
services, pain assessment, blood sampling, etc.
Cancer Xenografts - Price
- Subcutaneous Model is the placement of cells and tumor pieces just beneath the skin on the flank or hind leg. This is the common xenograft model for patient tumor propagation, simple tumor growth analysis, chemotherapeutic dose response analysis as well as some radiation studies.
- Orthotopic Model is the deposit of cells or tumor pieces in the anatomical location of cancer origin including renal capsule, spleen capsule, ovarian bursa, intra-tracheal, pancreas, intra-peritoneal, intra-vesicular/bladder, inter-coastal to the lungs, mammary fat pad, prostate, tibia and femur. This approach aims to mimic the tissue environment of a primary tumor more accurately than subcutaneous implantation.
- Metastases Model is the occurrence of transplantable
metastases from syngenic models, orthotopic xenograft models, tail
vein, and intra-cardiac injections of cells.
Surgical Services - Price List
We offer cardiovascular, castrations, catheterizations,
oophrectomies, thyroidectomies, and many others as needed to develop
the correct animal model for specific studies.
Our staff can advise and train investigators to perform and manage some or all parts of their studies themselves.