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- Info
Rekosh Publications

(selected from >80; reverse
chronological order)
- Ward AM, Rekosh D, Hammarskjold ML. (2009) Trafficking through the
Rev/RRE pathway is essential for efficient inhibition of human
immunodeficiency virus type 1 by an antisense RNA derived from the
envelope gene.J Virol. 2009 Jan;83(2):940-52. Epub 2008 Oct 29. PMCID:
PMC2612364
- Legiewicz M, Badorrek B., Turner K., Fabris D. , Hamm T.,
Rekosh D., Hammarskjold M-L and Le Grice S. (2008) Resistance to
RevM10 inhibition reflects a conformational switch in the HIV-1 Rev
response element Proc Natl Acad Sci, Proc Natl Acad Sci U S A. Sep
23;105(38):14365-70. Epub 2008 Sep 5. PMCID: PMC2567145
- Shuck-Lee D, Chen FF, Willard R, Raman S, Ptak R, Hammarskjold ML,
Rekosh D. (2008) Identification of Heterocyclic Compounds that Inhibit
Rev-RRE Function and Human Immunodeficiency Virus Type-1 Replication.
Antimicrob Agents Chemother. Sep;52(9):3169-79. Epub 2008 Jul 14.
PMCID: PMC2533482
- Olivieri KC, Scoggins RM, Broderick B, Chmura M, Alexander MA,
Hammarskjold ML, Rekosh D, and Camerini D.(2008) Nef does not
contribute to replication differences between R5 pre-AIDS and AIDS
HIV-1 clones from patient ACH142. Retrovirology. May 29;5(1):42.
PMCID: PMC2440386
- Medeiros MS, Arruda EA, Guerrant RL, Brown C, Hammarskjold ML,
Rekosh D, Lima AA. (2007) Genotype testing and antiretroviral
resistance profiles from HIV-1 patients experiencing therapeutic
failure in northeast Brazil. Braz J Infect
Dis. Aug;11(4):390-4.
- Swartz JE, Bor YC, Misawa Y, Rekosh D, Hammarskjold ML. (2007) The
shuttling SR protein 9G8 plays a role in translation of unspliced mRNA
containing a CTE. J Biol Chem. 282 19844-19853
- Olivieri, K.C. BS, Scoggins, R. M., Bor, Y-C, Matthews, A., Mark,
B.S. ,Taylor, J., Chenauskas, D, Hammarskjold, M.L., Rekosh D. and
Camerini, D. (2007) The Envelope Gene is a Cytopathic Determinant of
CCR5 Tropic HIV-1, Virology 358 23-38
- Bessong PO, Mphahlele J, Choge IA, Obi LC, Morris L, Hammarskjold
ML, Rekosh DM. (2006) Resistance Mutational Analysis of HIV Type 1
Subtype C among Rural South African Drug-Naive Patients Prior to
Large-Scale Availability of Antiretrovirals. AIDS Res Hum Retroviruses.
12 1306-1312
- Levesque L, Bor YC, Matzat LH, Jin L, Berberoglu S, Rekosh D,
Hammarskjold ML, Paschal BM. (2006) Mutations in tap uncouple RNA
export activity from translocation through the nuclear pore complex.Mol
Biol Cell. 17 931-43. PMCID: PMC1356601
- Bor YC, Swartz J, Morrison A, Rekosh D, Ladomery M, Hammarskjold
ML. (2006) The Wilms' tumor 1 (WT1) gene (+KTS isoform) functions with
a CTE to enhance translation from an unspliced RNA with a retained
intron. Genes Dev. 20 1597-1608. PMCID: PMC1482480
- Li, Y. Bor, Y.-C.,Misawa, Y, Xue, Y, Rekosh ,
D.,and M.-L. Hammarskjold (2006) The Tap/NXF1 Gene Contains a
Functional CTE in an Intron that is Retained in an Alternatively
Spliced mRNA, Nature 2006 443 234-237
- Alexander M, Bor YC, Ravichandran KS, Hammarskjold ML, Rekosh D.
(2004) Human immunodeficiency virus type 1 Nef associates with lipid
rafts to downmodulate cell surface CD4 and class I major
histocompatibility complex expression and to increase viral infectivity
J Virol. 781685-96. PMCID: PMC369412.
- Coyle JH, Guzik BW, Bor YC, Jin L, Eisner-Smerage L, Taylor SJ,
Rekosh D, Hammarskjold ML. (2003) Sam68 enhances the cytoplasmic
utilization of intron-containing RNA and is functionally regulated by
the nuclear kinase Sik/BRK.Mol Cell Biol. 23 92-103. PMCID:
PMC140664
- Jin L, Guzik BW, Bor YC, Rekosh D, Hammarskjold ML.(2003) Tap and
NXT promote translation of unspliced mRNA.Genes Dev 17 3075-3086.
PMCID: PMC305259
- Mierisch CM, Wilson HA, Turner MA, Milbrandt TA, Berthoux L,
Hammarskjold ML, Rekosh D, Balian G, Diduch DR. (2003) Chondrocyte
transplantation into articular cartilage defects with use of calcium
alginate: the fate of the cells.J Bone Joint Surg Am.
85-A(9):1757-1767.
- Milbrandt T, Berthoux L, Christenson V, Baumbusch C, Rekosh D,
Balian G, Diduch D.Tracing transduced cells in osteochondral
defects. (2003) J Pediatr Orthop. 23 430-436.
- Walk,S.F., Alexander, M., Hammarskjold,M.-L., Rekosh, D.M.and
Ravichandran, K.S. (2001) Design and Use of an Inducibly-Activated
HIV-1 Nef to Study Immune Modulation, J. Virol., J Virol. 75:834-843.
PMCID: PMC113979
- Guzik, B.W., Levesque, L.,Prasad, S, .Bor, Y.-C., Black,
B.E., Paschal, B., Rekosh, D. and Hammarskjöld,M.-L.,(2001)
NXT1/p15 is a Crucial Cellular Cofactor in TAP Dependent Export of
Intron-Containing RNA in Mammalian Cells, Mol Cell Biol.21:2545-2554.
PMCID: PMC86886
- Chazal N, Singer G, Aiken C, Hammarskjold ML, and Rekosh D.(2001)
Human Immunodeficiency Virus Type 1 Particles Pseudotyped with Envelope
Proteins That Fuse at Low pH No Longer Require Nef for Optimal
Infectivity. J Virol.75 4014-4018. PMCID: PMC114896
- Mouland, A.J., Xu, H, Cui, H, Krueger, W. Munro, T.P.,
Prasol, M., Mercier,J. ,Rekosh,D. Smith, R, Cohen, E.A., Elisa
Barbarese, E. and Carson, J.H. (2001) RNA Trafficking Signals in Human
Immunodeficiency Virus Type 1. Mol Cell Biol. 21 2133-2143. PMCID:
PMC86835
- Lévesque,L. Guzik, G, Guan, T., Coyle,J. Black,
B.E., Rekosh,D. Hammarskjöld, M.-L. and Paschal, B.M. (2001) RNA
export mediated by tap Involves NXT1-dependent interactions with the
nuclear pore complex J. Biol. Chem. 276 44953-44962.
- Giordano, V., Jin, D-Y., Rekosh, D. and Jeang, K-T. (2000)
Enhanced Anti-viral Effect from Intravirion Targeting of a Functional
Anti-HIV Ribozyme. Virology, Virology 267 174-184
- Helga-Maria, C., Hammarskjöld, M-L. and Rekosh, D. (1999) An
Intact TAR Element and Cytoplasmic Localization Are Necessary for
Efficient Packaging of HIV Type 1 Genomic RNA. J. Virol.
73:4127-4135. PMCID: PMC104192
- Hamm, T. E., Rekosh, D. and Hammarskjöld, M-L. (1999) Selection and
Characterization of HIV-1 Mutants that are Resistant to Inhibition by
the Transdominant Negative RevM10 Protein. J. Virol., 73:5741-5747.
PMCID: PMC112634
- Ernst, R.K., Bray, M., Rekosh, D. and Hammarskjöld, M.-L. (1997) A
structured retroviral RNA element that mediates nucleocytoplasmic
export of intron-containing RNA Mol. Cell Biol 17: 135-144. PMCID:
PMC231737
- Ernst, R.K., Bray, M., Rekosh, D. and Hammarskjöld, M.-L. (1997),
Secondary structure and mutational analysis of the Mason-Pfizer monkey
virus RNA constitutive transport element. RNA, 3: 210-222. PMCID:
PMC1369474
- Pasquinelli, A. E., Ernst, R. K., Lund,E., Grimm, C., Zapp, M. L.,
Rekosh,D., Hammarskjöld, M.-L. and Dahlberg, J.E. (1997) The
Constitutive Transport Element (CTE) of Mason-Pfizer Monkey Virus
(MPMV) Accesses a Cellular mRNA Export Pathway, EMBO J. 16:
7500-7510Hammarskjöld, M-L (1997) Regulation of retroviral RNA
transport ,Sem. Cell. Develop. Biol., 8:83-90. PMCID: PMC1170349
- Srinivasakumar, N., Chazal, N., Helga-Maria, C., Prasad, S.,
Hammmarskjöld, M.-L., and Rekosh, D (1997). The effect of viral
regulatory protein expression on gene delivery using human
immunodeficiency virus type 1 vectors produced in stable packaging cell
lines J. Virol 71:5841-5848. PMCID: PMC191839
- Dundr, M. Leno, M., Lewis, N., Rekosh, D., Hammarskjöld, M.L. and
Olson, M. O.J. (1996) Location of the HIV-1 rev protein during mitosis:
Inactivation of the nuclear export signal alters the pathway for
postmitotic reentry, J. of Cell Sci.,109:2239-2251
- Orsini, M.J., Thakur, A.N., Andrews, W.W., Hammarskjöld, M.-L. and
Rekosh, D.M. (1995) Expression and purification of the HIV-1 Rev
protein and its use in the generation of monoclonal antibodies. AIDS
Research and Human Retroviruses, 11: 945-953
- Srinivasakumar, N., Hammarskjöld, M.-L., and Rekosh, D.M. (1995)
Characterization of Deletion Mutations in the Capsid Region of Human
Immunodeficiency Virus Type 1 That Affect Particle Formation and
Gag-Pol Precursor Incorporation. J. Virol. 69: 6106-6114. PMCID:
PMC189507
- Berkowitz, R. D., Hammarskjöld, M.-L., Helga-Maria, C., Rekosh, D.
and Goff, S. P. (1995) 5' Regions of HIV-1 RNAs Are Not Sufficient for
Encapsidation: Implications for the HIV-1 Packaging Signal. Virology
212: 718- 723.
- Dundr, M., Leno, G. H., Hammarskjöld, M.-L., Rekosh, D.,
Helga-Maria, C. and Olson, M. O. J. (1995) The roles of nucleolar
structure and function in the sub cellular location of the HIV-1 Rev
protein. J. of Cell Sci. 108: 2811-2823
- Mak, J., Jiang, M., Wainberg M.A.,Hammarskjöld, M.-L., Rekosh, D.
and Kleiman, L.(1994) Role of Pr160 in mediating the selective
incorporation of tRNAlys into HIV-1 particles J. Virol. 68:
2065-2072. PMCID: PMC236680
- Ciccarelli, R.B., Winter, L.A., Lorenz, R., Harris, A.L., Crawford,
A.C., Bailey, T.R., Singh, B., Hammarskjöld, M. L., Rekosh, D. and
Hughes, J.V. (1994) Inhibition of the cellular rev response and HIV-1
replication by 8-alkyl-2-(4-pyridyl)pyrido[2,3-d]pyrimidin-5(8H)-ones.
Antiviral Chem and Chemo, 5,169-175.
- Hammarskjold ML, Li H, Rekosh D, Prasad S. (1994) Human
immunodeficiency virus env expression becomes Rev-independent if the
env region is not defined as an intron. J Virol. 1994 68 951-958.
PMCID: PMC236533
- Bray, M., Prasad, S. Dubay, J.W., Hunter, E. Jeang,K.T.,
Rekosh, D. and Hammarskjold-M-L. (1994) A small element from the
Mason-Pfizer monkey virus genome makes human immunodeficiency virus
type 1 expression and replication Rev-independent. Proc. Natl.
Acad.Sci.(USA) 91: 1256-1260. PMCID: PMC43136
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