Rekosh Publications

Rekosh Publications

Myles Thaler Center

(selected from >80; reverse chronological order)

  • Ward AM, Rekosh D, Hammarskjold ML. (2009) Trafficking through the Rev/RRE pathway is essential for efficient inhibition of human immunodeficiency virus type 1 by an antisense RNA derived from the envelope gene.J Virol. 2009 Jan;83(2):940-52. Epub 2008 Oct 29. PMCID: PMC2612364
  • Legiewicz M, Badorrek B., Turner K., Fabris D. , Hamm T., Rekosh D., Hammarskjold M-L and Le Grice S. (2008) Resistance to RevM10 inhibition reflects a conformational switch in the HIV-1 Rev response element Proc Natl Acad Sci, Proc Natl Acad Sci U S A. Sep 23;105(38):14365-70. Epub 2008 Sep 5. PMCID: PMC2567145
  • Shuck-Lee D, Chen FF, Willard R, Raman S, Ptak R, Hammarskjold ML, Rekosh D. (2008) Identification of Heterocyclic Compounds that Inhibit Rev-RRE Function and Human Immunodeficiency Virus Type-1 Replication. Antimicrob Agents Chemother. Sep;52(9):3169-79. Epub 2008 Jul 14. PMCID: PMC2533482
  • Olivieri KC, Scoggins RM, Broderick B, Chmura M, Alexander MA, Hammarskjold ML, Rekosh D, and Camerini D.(2008) Nef does not contribute to replication differences between R5 pre-AIDS and AIDS HIV-1 clones from patient ACH142. Retrovirology. May 29;5(1):42. PMCID: PMC2440386
  • Medeiros MS, Arruda EA, Guerrant RL, Brown C, Hammarskjold ML, Rekosh D, Lima AA. (2007) Genotype testing and antiretroviral resistance profiles from HIV-1 patients experiencing therapeutic failure in northeast Brazil. Braz J Infect Dis. Aug;11(4):390-4.
  • Swartz JE, Bor YC, Misawa Y, Rekosh D, Hammarskjold ML. (2007) The shuttling SR protein 9G8 plays a role in translation of unspliced mRNA containing a CTE. J Biol Chem. 282 19844-19853
  • Olivieri, K.C. BS, Scoggins, R. M., Bor, Y-C, Matthews, A., Mark, B.S. ,Taylor, J., Chenauskas, D, Hammarskjold, M.L., Rekosh D. and Camerini, D. (2007) The Envelope Gene is a Cytopathic Determinant of CCR5 Tropic HIV-1, Virology 358 23-38
  • Bessong PO, Mphahlele J, Choge IA, Obi LC, Morris L, Hammarskjold ML, Rekosh DM. (2006) Resistance Mutational Analysis of HIV Type 1 Subtype C among Rural South African Drug-Naive Patients Prior to Large-Scale Availability of Antiretrovirals. AIDS Res Hum Retroviruses. 12 1306-1312
  • Levesque L, Bor YC, Matzat LH, Jin L, Berberoglu S, Rekosh D, Hammarskjold ML, Paschal BM. (2006) Mutations in tap uncouple RNA export activity from translocation through the nuclear pore complex.Mol Biol Cell. 17 931-43. PMCID: PMC1356601
  • Bor YC, Swartz J, Morrison A, Rekosh D, Ladomery M, Hammarskjold ML. (2006) The Wilms' tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron. Genes Dev. 20 1597-1608. PMCID: PMC1482480
  • Li, Y. Bor, Y.-C.,Misawa, Y, Xue, Y, Rekosh , D.,and M.-L. Hammarskjold (2006) The Tap/NXF1 Gene Contains a Functional CTE in an Intron that is Retained in an Alternatively Spliced mRNA, Nature 2006 443 234-237
  • Alexander M, Bor YC, Ravichandran KS, Hammarskjold ML, Rekosh D. (2004) Human immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity J Virol. 781685-96. PMCID: PMC369412.
  • Coyle JH, Guzik BW, Bor YC, Jin L, Eisner-Smerage L, Taylor SJ, Rekosh D, Hammarskjold ML. (2003) Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.Mol Cell Biol. 23 92-103. PMCID: PMC140664
  • Jin L, Guzik BW, Bor YC, Rekosh D, Hammarskjold ML.(2003) Tap and NXT promote translation of unspliced mRNA.Genes Dev 17 3075-3086. PMCID: PMC305259
  • Mierisch CM, Wilson HA, Turner MA, Milbrandt TA, Berthoux L, Hammarskjold ML, Rekosh D, Balian G, Diduch DR. (2003) Chondrocyte transplantation into articular cartilage defects with use of calcium alginate: the fate of the cells.J Bone Joint Surg Am. 85-A(9):1757-1767.
  • Milbrandt T, Berthoux L, Christenson V, Baumbusch C, Rekosh D, Balian G, Diduch D.Tracing transduced cells in osteochondral defects. (2003) J Pediatr Orthop. 23 430-436.
  • Walk,S.F., Alexander, M., Hammarskjold,M.-L., Rekosh, D.M.and Ravichandran, K.S. (2001) Design and Use of an Inducibly-Activated HIV-1 Nef to Study Immune Modulation, J. Virol., J Virol. 75:834-843. PMCID: PMC113979
  • Guzik, B.W., Levesque, L.,Prasad, S, .Bor, Y.-C., Black, B.E., Paschal, B., Rekosh, D. and Hammarskjöld,M.-L.,(2001) NXT1/p15 is a Crucial Cellular Cofactor in TAP Dependent Export of Intron-Containing RNA in Mammalian Cells, Mol Cell Biol.21:2545-2554. PMCID: PMC86886
  • Chazal N, Singer G, Aiken C, Hammarskjold ML, and Rekosh D.(2001) Human Immunodeficiency Virus Type 1 Particles Pseudotyped with Envelope Proteins That Fuse at Low pH No Longer Require Nef for Optimal Infectivity. J Virol.75 4014-4018. PMCID: PMC114896
  • Mouland, A.J., Xu, H, Cui, H, Krueger, W. Munro, T.P., Prasol, M., Mercier,J. ,Rekosh,D. Smith, R, Cohen, E.A., Elisa Barbarese, E. and Carson, J.H. (2001) RNA Trafficking Signals in Human Immunodeficiency Virus Type 1. Mol Cell Biol. 21 2133-2143. PMCID: PMC86835
  • Lévesque,L. Guzik, G, Guan, T., Coyle,J. Black, B.E., Rekosh,D. Hammarskjöld, M.-L. and Paschal, B.M. (2001) RNA export mediated by tap Involves NXT1-dependent interactions with the nuclear pore complex J. Biol. Chem. 276 44953-44962.
  • Giordano, V., Jin, D-Y., Rekosh, D. and Jeang, K-T. (2000) Enhanced Anti-viral Effect from Intravirion Targeting of a Functional Anti-HIV Ribozyme. Virology, Virology 267 174-184
  • Helga-Maria, C., Hammarskjöld, M-L. and Rekosh, D. (1999) An Intact TAR Element and Cytoplasmic Localization Are Necessary for Efficient Packaging of HIV Type 1 Genomic RNA. J. Virol. 73:4127-4135. PMCID: PMC104192
  • Hamm, T. E., Rekosh, D. and Hammarskjöld, M-L. (1999) Selection and Characterization of HIV-1 Mutants that are Resistant to Inhibition by the Transdominant Negative RevM10 Protein. J. Virol., 73:5741-5747. PMCID: PMC112634
  • Ernst, R.K., Bray, M., Rekosh, D. and Hammarskjöld, M.-L. (1997) A structured retroviral RNA element that mediates nucleocytoplasmic export of intron-containing RNA Mol. Cell Biol 17: 135-144. PMCID: PMC231737
  • Ernst, R.K., Bray, M., Rekosh, D. and Hammarskjöld, M.-L. (1997), Secondary structure and mutational analysis of the Mason-Pfizer monkey virus RNA constitutive transport element. RNA, 3: 210-222. PMCID: PMC1369474
  • Pasquinelli, A. E., Ernst, R. K., Lund,E., Grimm, C., Zapp, M. L., Rekosh,D., Hammarskjöld, M.-L. and Dahlberg, J.E. (1997) The Constitutive Transport Element (CTE) of Mason-Pfizer Monkey Virus (MPMV) Accesses a Cellular mRNA Export Pathway, EMBO J. 16: 7500-7510Hammarskjöld, M-L (1997) Regulation of retroviral RNA transport ,Sem. Cell. Develop. Biol., 8:83-90. PMCID: PMC1170349
  • Srinivasakumar, N., Chazal, N., Helga-Maria, C., Prasad, S., Hammmarskjöld, M.-L., and Rekosh, D (1997). The effect of viral regulatory protein expression on gene delivery using human immunodeficiency virus type 1 vectors produced in stable packaging cell lines J. Virol 71:5841-5848. PMCID: PMC191839
  • Dundr, M. Leno, M., Lewis, N., Rekosh, D., Hammarskjöld, M.L. and Olson, M. O.J. (1996) Location of the HIV-1 rev protein during mitosis: Inactivation of the nuclear export signal alters the pathway for postmitotic reentry, J. of Cell Sci.,109:2239-2251
  • Orsini, M.J., Thakur, A.N., Andrews, W.W., Hammarskjöld, M.-L. and Rekosh, D.M. (1995) Expression and purification of the HIV-1 Rev protein and its use in the generation of monoclonal antibodies. AIDS Research and Human Retroviruses, 11: 945-953
  • Srinivasakumar, N., Hammarskjöld, M.-L., and Rekosh, D.M. (1995) Characterization of Deletion Mutations in the Capsid Region of Human Immunodeficiency Virus Type 1 That Affect Particle Formation and Gag-Pol Precursor Incorporation. J. Virol. 69: 6106-6114. PMCID: PMC189507
  • Berkowitz, R. D., Hammarskjöld, M.-L., Helga-Maria, C., Rekosh, D. and Goff, S. P. (1995) 5' Regions of HIV-1 RNAs Are Not Sufficient for Encapsidation: Implications for the HIV-1 Packaging Signal. Virology 212: 718- 723.
  • Dundr, M., Leno, G. H., Hammarskjöld, M.-L., Rekosh, D., Helga-Maria, C. and Olson, M. O. J. (1995) The roles of nucleolar structure and function in the sub cellular location of the HIV-1 Rev protein. J. of Cell Sci. 108: 2811-2823
  • Mak, J., Jiang, M., Wainberg M.A.,Hammarskjöld, M.-L., Rekosh, D. and Kleiman, L.(1994) Role of Pr160 in mediating the selective incorporation of tRNAlys into HIV-1 particles J. Virol. 68: 2065-2072. PMCID: PMC236680
  • Ciccarelli, R.B., Winter, L.A., Lorenz, R., Harris, A.L., Crawford, A.C., Bailey, T.R., Singh, B., Hammarskjöld, M. L., Rekosh, D. and Hughes, J.V. (1994) Inhibition of the cellular rev response and HIV-1 replication by 8-alkyl-2-(4-pyridyl)pyrido[2,3-d]pyrimidin-5(8H)-ones. Antiviral Chem and Chemo, 5,169-175.
  • Hammarskjold ML, Li H, Rekosh D, Prasad S. (1994) Human immunodeficiency virus env expression becomes Rev-independent if the env region is not defined as an intron. J Virol. 1994 68 951-958. PMCID: PMC236533
  • Bray, M., Prasad, S. Dubay, J.W., Hunter, E. Jeang,K.T., Rekosh, D. and Hammarskjold-M-L. (1994) A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent. Proc. Natl. Acad.Sci.(USA) 91: 1256-1260. PMCID: PMC43136