Polycystic Ovary Syndrome

Studies for Women

Study #1:
ACUTE EFFECTS OF PROGESTERONE ON LH SECRETION IN PCOS AND CONTROLS
(IRB-HSR # 13368)

• The goal is to learn how progesterone acutely changes LH secretion.
• We are recruiting women with and without PCOS, 18-35 years old, with a BMI ≤ 40 kg/m².
• Study requires 3 brief outpatient visits and two 26-hour (overnight) admissions (6pm-8pm).
• Participants will take one oral dose of progesterone, and will wear estrogen patches on two separate occasions (for 4 days each time).
• Sleep will be formally monitored.
• Compensation = $300.

Contact Anne Gabel at pcos@virginia.edu or (434) 243-6911 for more information.

Study #2:
EFFECT OF HYPERANDROGENEMIA ON SLEEP-WAKE CHANGES OF LH FREQUENCY
(IRB-HSR # 14067)

• The goal is to assess whether testosterone influences sleep-wake differences of LH secretion.
• We are recruiting women with and without PCOS, 18-35 years old, no upper BMI limit.
• Study requires 3 brief outpatient visits and two 17-hour (overnight) admissions (2pm-7am).
• Participants will take flutamide for about 28 days.
• Sleep will be formally monitored.
• Compensation = $300.

Contact:     Anne Gabel at pcos@virginia.edu or (434) 243-6911 for more information.