Lucy F. Pemberton
Associate Professor of Microbiology,
Immunology, and Cancer Biology

Representative publications:

Keck, K.M. and Pemberton, L.F. (2011) Histone chaperones link histone nuclear import and chromatin assembly. Biochim Biophys Acta. [Epub ahead of print].
Abstract

Keck K.M. and Pemberton L.F. (2011) Interaction with the Histone Chaperone Vps75 Promotes Nuclear Localization and HAT Activity of Rtt109 In Vivo.Traffic.12:826-39.
Abstract

Straube K, Blackwell J.S. Jr. and Pemberton L.F. (2010) Nap1 and Chz1 have separate Htz1 nuclear import and assembly functions. Traffic. 11:185-97.
Abstract

Calvert M, Lannigan, J.A. and Pemberton, L.F. (2008) Optimization of yeast cell cycle analysis and morphological characterization by multispectral imaging flow cytometry. Cytometry A. 73A:825-833.
Abstract

Del Rosario B.C and Pemberton, L.F. (2008) Nap1 links transcription elongation, chromatin assembly and mRNP biogenesis. Mol. Cell. Biol. 28: 2113-2124.
Abstract

Calvert M, Keck K, Ptak C, Shabanowitz J, Hunt D and Pemberton, L.F. (2008). Phosphorylation by CK2 regulates Nap1 localization and function. Mol. Cell. Biol. 28: 1313-1325.
Abstract

Blackwell Jr, J.S., Wilkinson, S.T., Mosammaparast, N. and Pemberton, L.F. (2007) Mutational Analysis of H3 and H4 Amino Termini Reveals Distinct Roles in Nuclear Import. J. Biol. Chem. 282, 20142-50.
Abstract

Pemberton, L.F. and Paschal, B.P. Scientists Share Nuclear Secrets at Jekyll Island (2006) Traffic. 7, 751-760.

Hodges, J.L., Leslie, J.H., Mosammaparast, N., Guo, Y., Shabanowitz, J., Hunt, D.F., and Pemberton, L.F. (2005). Nuclear import of TFIIB is mediated by Kap114p, a karyopherin with multiple cargo binding domains. MBC. 16, 3200-3210.

Mosammaparast, N. Del Rosario, B. D, and Pemberton, L.F. (2005) Modulation of Histone Deposition by the Karyopherin Kap114. Mol Cell Biol. 25, 1764-1778.

Pemberton, L.F. and Paschal, B.P. Mechanisms of Receptor-Mediated Nuclear Import and Nuclear Export. (2005) Traffic. 6, 187-198.

Loch CM, Mosammaparast N, Miyake T, Pemberton LF, Li R. (2004) Functional and physical interactions between autonomously replicating sequence-binding factor 1 and the nuclear transport machinery. Traffic 5 :925-35

Mosammaparast N, and Pemberton LF. (2004) Karyopherins: from nuclear-transport mediators to nuclear-function regulators. Trends Cell Biol. 14:547-56.

Mosammaparast, N, Ewart, C. S., and Pemberton, L. F. (2002) A role for nucleosome assembly protein 1 in the nuclear transport of histones H2A and H2B. EMBO Journal. 21, 6527-6538.

Mosammaparast, N, Guo, Y., Shabanowitz, J., Hunt, D.F. and Pemberton, L.F. (2002) Pathways mediating the nuclear import of histone H3 and H4 in yeast. J. Biol Chem. 277, 862-868.

Mosammaparast, N., Jackson, K.R., Guo, Y., Brame, C.J., Shabanowitz, J., Hunt, D.F., and Pemberton, L.F. (2001) Nuclear import of histone H2A and H2B is mediated by a network of karyopherins. J. Cell Biol. 153, 251-262.

Pemberton, L. F., Rosenblum, J.S. and Blobel, G. (1999) Nuclear import of the TATA binding protein: mediation by the karyopherin Kap114p and a possible mechanism for intranuclear targeting. J. Cell Biol. 145, 1407-1417.

Albertini, M., Pemberton, L.F., Rosenblum, J.S. and Blobel, G. (1998) A novel nuclear import pathway for the transcription factor TFIIS. J. Cell Biol. 143, 1447-1455.

Rosenblum, J.S., Pemberton, L.F., Bonifaci, N. and Blobel, G. (1998) Nuclear import and the evolution of a multifunctional RNA-binding protein. J. Cell Biol. 143, 887-899.

Pemberton, L.F., Blobel, G. and Rosenblum, J.S. (1998) Transport routes through the nuclear pore complex. Curr. Opin. Cell Biol. 10, 392-399.

Pemberton, L.F., Rosenblum, J.S. and Blobel, G. (1997) A distinct and parallel pathway for the nuclear import of an mRNA-binding protein. J. Cell Biol. 139, 1645-1653.

PubMed