Tgifs and development
Taniguchi, K., Anderson, A.E., Sutherland, A.E. and Wotton, D.
(2012). Loss of Tgif function causes holoprosencephaly by disrupting
the Shh signaling pathway. PLoS Genetics. In Press.
Powers, S.E., Taniguchi, K., Yen, W., Melhuish, T.A., Shen, J.,
Walsh, C.A., Sutherland, A.E. and Wotton, D. (2010). Tgif1 and Tgif2
regulate Nodal signaling and are required for gastrulation.
Development. 137, 249-259.
Abstract
Bartholin, L., Melhuish, T.A., Powers, S.E., Goddard-Leon, S.,
Treilleux, I., Sutherland, A.E. and Wotton, D. (2008). Maternal Tgif is
required for vascularization of the embryonic placenta. Dev.
Biol. 319, 285-297.
Abstract
El-Jaick, K., Powers, S.E., Bartholin, L., Myers, K.R., Hahn, J.,
Lacbawan, F., Roessler, E., Wotton, D. and Muenke, M. (2007).
Functional analysis of mutations in TGIF associated with
holoprosencephaly. Mol. Genet. Metab. 90, 97-111.
Abstract
Tgifs and transcriptional regulation
Bjerke, G.A., Hyman-Walsh, C. and Wotton, D. (2011). Cooperative
transcriptional activation by Klf4, Meis2, and Pbx1. Mol. Cell
Biol. 31(18), 3723-33.
Abstract
Melhuish T.A., Chung, D.D., Bjerke, G.A. and Wotton, D. (2010).
Tgif1 represses apolipoprotein gene expression in liver. J Cell
Biochem. 111(2), 380-90.
Abstract
Hyman-Walsh, C., Bjerke, G.A., and Wotton, D. (2010). An
autoinhibitory effect of the homothorax domain of Meis2. FEBS
J. 277(12), 2584-97.
Abstract
Melhuish, T.A. and Wotton, D. (2006). The Tgif2 gene contains a
retained intron within the coding sequence. BMC. Mol. Biol. 7,
2.
Abstract
Bartholin, L., Powers, S.E., Melhuish, T.A., Lasse, S.H., Weinstein,
M. and Wotton, D. (2006). Tgif inhibits retinoid signaling. Mol.
Cell. Biol. 16, 990-1001.
Abstract
Hyman, C.A., Bartholin, L., Newfeld, S.J., and Wotton, D. (2003).
Drosophila TGIF proteins are transcriptional activators.
Mol. Cell. Biol. 23, 9262-9274.
Abstract
Melhuish, T.A., Gallo, C.M. and Wotton, D. (2001). TGIF2 interacts
with histone deacetylase and represses transcription. J. Biol.
Chem. 276, 32109-32114.
Abstract
Melhuish, T.A. and Wotton, D. (2000). The interaction of the
Carboxyl terminus binding Protein with the Smad corepressor TGIF is
disrupted by a holoprosencephaly mutation in TGIF. J. Biol.
Chem. 275, 39762-39766.
Abstract
SUMOylation
Merrill, J.C., Kagey, M.H., Melhuish, T.A., Powers, S.E., Zerlanko,
B.J. and Wotton, D. (2010). Inhibition of CtBP1 activity by
Akt-mediated phosphorylation. J. Mol. Biol. 398(5),
657-71.
Abstract
Merrill, J.C., Melhuish, T.A., Kagey, M.H., Yang, S.H., Sharrocks,
A.D. and Wotton, D. (2010). A role for non-covalent SUMO interaction
motifs in Pc2/CBX4 E3 activity. PLoS ONE. 5, e8794.
Abstract
Kagey, M.H., Melhuish, T.A., Powers, S.E. and Wotton, D. (2005).
Multiple activities contribute to Pc2 E3 function. EMBO J. 24,
108-119.
Abstract
Kagey, M.H., Melhuish, T.A. and Wotton, D. (2003). The Polycomb
protein Pc2 is a SUMO E3. Cell. 113, 127-137.
Abstract
