Eto, M., Brautigan, D.L. (2012) Endogenous inhibitor proteins that connect Ser/Thr kinases and phosphatases in cell signaling. IUBMB Life. 64(9): 732-9. PMCID: PMC3422418 [Available on 2013/9/1].
Abstract

Griner, E.M., Churchill, M.E., Brautigan, D.L., Theodorescu, D. (2012) PKCα phosphorylation of RhoGDI2 at Ser31 disrupts interactions with Rac1 and decreases GDI activity. Oncogene. doi: 10.1038/onc.2012.124. [Epub ahead of print]. PMID: 22469974.
Abstract

Brautigan, D.L. (2012) Protein Ser/Thr Phosphatases: The Ugly Ducklings of Cell Signaling. Journal of Federation of European Biochemical Societies doi: 10.1111/j.1742-4658.2012.08609.x. [Epub ahead of print]. PMID: 22519956.
Abstract

Hosing, A.S., Valerie, N.C., Dziegielewski, J., Brautigan, D.L., and Larner, J.M. (2012) SAPSR1 is a bidentate anchor for targeting protein phosphatase-6 to DNA-PK. J. Biol. Chem. [Epub ahead of print]. PMID: 22298787.
Abstract

Edelson, J.R., Brautigan, D.L. (2011) The Discodermia calyx Toxin Calyculin A enhances Cyclin D1 Phosphorylation and Degradation, and Arrests Cell Cycle Progression in Human Breast Cancer Cells. Toxins (Basel). 3(1): 105-19. PMCID: PMC3210456.
Abstract

Hall, E.H., Gurel, V., Dahlberg, A.E., McMichael, J., and Brautigan, D.L. (2011) Inhibition of human breast cancer Matrigel invasion by Streptolysin O activation of the EGF receptor ErbB1. Cell Signal. 23(12): 1972-7. PMID: 21787862.
Abstract

Sami, F., Smet-Nocca, C., Khan, M., Landrieu, I., Lippens, G., and Brautigan, D.L. (2011) Molecular basis for an ancient partnership between prolyl isomerase Pin1 and phosphatase inhibitor-2. Biochemistry. 50(30): 6567-78. PMID: 21714498.
Abstract

Martín-Montalvo, A., González-Mariscal, I., Padilla, S., Ballesteros, M., Brautigan, D.L.,  Navas^, P. and Santos-Ocaña, C. (2011) Respiratory-induced coenzyme Q biosynthesis is regulated by a phosphorylation cycle of Coq7p. Biochem. J. 440(1): 107-14. PMID: 21812761.
Abstract

Molhoek, K. R., Erdag, G., Rasamny, Jk, Murphy, C., Deacon, D., Patterson, J. W., Slingluff, Jr., C. L., and Brautigan, D. L. (2011) VEGFR-2 Expression in Human Melanoma: Revised Assessment. Internal. J. Cancer. 129(12): 2807-15.  PMID: 21544800.
Abstract

Molhoek, K. R., Shada, A. L., Smolkin, M., Chowbina, S., Papin, J., Brautigan, D. L. and Slingluff, Jr., C. L. (2011) Comprehensive analysis of receptor tyrosine kinase activation in human melanomas reveals autocrine signaling through IGF-1R. Melanoma Res. 21(4): 274-84. PMCID: PMC3131461.
Abstract

Everett, A. D., Yang, J., Rahman, M., Dulloor, P. and Brautigan, D.L. (2011) Mitotic Phosphorylation activates hepatoma-derived growth factor as a mitogen.  BMC Cell Biol. 12: 15. doi:10.1186/1471-2121-12-15.  PMID: PMC3094319.
Abstract

Edelson, J. and Brautigan, D. L. (2011) The Discodermia calyx toxin calyculin A enhances cyclin D1 phosphorylation and degradation and arrests cell cycle progression in human breast cancer cells. Toxins 3: 105-119. doi:10.3390/toxins3010105

Wang H., Owens C., Chandra N., Conaway M.R., Brautigan D.L., and Theodorescu D. (2010) Phosphorylation of RaIB is Important for Bladder Cancer Cell Growth and Metastasis. Cancer Res. 70(21): 8760-9. PMCID: PMC3025490.
Abstract

Larner J., Brautigan D.L., and Thorner M.O. (2010) D-Chiro-Inositol Glycans in Insulin Signaling and Insulin Resistance. Mol. Med. 16(11-12): 543-52. PMID: 20811656.
Abstract

Emily H. Hall, Jeremy L. Balsbaugh, Kristie L. Rose, Jeffrey Shabanowitz, Donald F. Hunt, and David L. Brautigan (2010) Comprehensive Analysis of Phosphorylation Sites in Tensin1 Reveals Regulation by p38MAPK. Mol Cell Proteomics. 9(12): 2853-63.  PMCID: PMC3101865.
Abstract

Ohama T., Braugitan D.L. (2010) Endotoxin conditioning induces VCP/p97-mediated and inducible nitric-oxide synthase-dependend Tyr284 nitration in protein phosphatase 2A. J. Biol. Chem. 285(12): 8711-8. PMCID: PMC2838294.
Abstract

Broglie, P., Matsumoto, K., Akira, S., Brautigan, D. L., and Ninimiya-Tsuji, J. (2010) Transforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway. J. Biol. Chem. 285(4): 2333-9 PMCID: PMC2807291 Epublished Dec. 2, 2009.
Abstract

Hans, S. K., Camara, F., Altiti, A., Martin-Montalvo, A., Brautigan, D. L., Heimark, D., Larner, J., Grindrod, S., Brown, M. L. And Mootoo, D. R. (2010) Synthesis of C-glycoside analogues of beta-galactosamine-(1-4)-3-O-methyl-D-chiro-inositol and assay as activator of protein phosphatases PDHP and PP2Calpha. Bioorg. Med. Chem. 18(3): 1103-10.  doi:10.1016/j.bmc.2009.12.056 PMID:20079654.
Abstract

Hall, E. H., Daugherty, A. E., Choi, C. K., Horwitz, A. R., and Brautigan, D. L. (2009) Tensin 1 requires protein phosphatase 1alpha in addition to Rho(GAP) DLC-1 to control cell polarization, migration and invasion. J. Biol. Chem. 284(50): 34713-34722. Epublished October 13, 2009 PMCID:PMC2787334.
Abstract

Guergnon, J., Derewenda, U., Edelson, J. R., and Brautigan, D. L. (2009) Mapping of Protein Phosphatase-6 Association with its SAPS Domain Regulatory Subunit Using a Model of Helical Repeats. BMC Biochemistry 10:24. PMCID:PMC2765987.
Abstract

Mi, J., Bolesta, E., Brautigan, D.L., and Larner, J.M. (2009) PP2A Regulates Ionizing Radiation-induced Apoptosis through Ser46 phosphorylation of p53.  Mol. Cancer Ther. 8(1): 135-140. PMID 19139122.
Abstract

Molhoek, K., McSkimming, C. C., Olson, W. C, Brautigan, D. L. and Slingluff, Jr., C. L. (2009) Apoptosis of CD4+CD25high T cells in response to Sirolimus requires activation of T cell receptor and is modulated by IL-2. Cancer Immunol. Immunother. 58(6): 867-876 Epublished Oct. 8, 2008 PMCID:PMC2688807.
Abstract

Mi, J., Dziegielewski, J., Bolesta, E., Brautigan, D.L., and Larner, J.M. (2009) Activation of DNA-PK by ionizing radiation is mediated by protein phosphatase-6. PLoS One 4(2): e4395. PMCID: PMC2634843.
Abstract

Morales-Johansson, H., Puria, R., Brautigan, D. L., and Cardenas, M. E. (2009) Human protein phosphatase PP6 regulatory subunits provide Sit4-dependent and rapamycin-sensitive Sap function in Saccharomyces cerevisiae. PLoS One 4(7): e6331 doi:10.1371/journal.pone.0006331 PMCID: PMC2708350.
Abstract

Li, M. Stukenberg, P. T. and Brautigan, D. L. (2008) "Binding of Phosphatase Inhibitor-2 to  Prolyl Isomerase Pin1 Modifies Specificity for Mitotic Phosphoproteins" Biochemistry 47(1): 292-300  PMID 18062707

Stefansson, B., Ohama, T., Daugherty, A.E. and Brautigan, D.L. (2008) Protein Phosphatase PP6 Subunits Composed of Ankyrin Repeats. Biochemistry, 47(5), 1442-1451 PMID 18186651

Fuller, B. G., Lampson, M. A., Foley, E. A., Rosasco-Nitcher, S., Le, K. V., Tobelman, P., Brautigan, D.L., Stukenberg, P.T., and Kapoor, T.M. (2008) "Midzone Activation of Aurora B in Anaphase Produces an Intracellular Phosphorylation Gradient" Nature 453: 1132-1136. PMCID: PMC2724008

Molhoek, K. R., Griesemann, H.,  Shu, J., Gershenwald, J. E., Brautigan, D. L. and C. L. Slingluff, Jr. (2008) "Human melanoma cytolysis by combined inhibition of VEGF/VEGFR-2 autocrine growth loop and of mTOR." Cancer Res. 68(11): 4392-4397. PMCID:PMC2727753

Yoo, S. J., Jimenez, R.H., Sanders, J. A., Boylan, J. M., Brautigan, D. L. and Gruppuso, P. A. (2008) "The 4-Containing Form of Protein Phosphatase 2A in Liver and Hepatic Cells" J. Cell. Biochem. 105(1): 290-300. PMCID:PMC2597445

Prickett, T.D., Ninomiya-Tsuji, J., Muratore, T. L., Shabanowitz, J., Hunt, D.F.  and Brautigan, D. L. (2008) "TAB4 stimulates TAK1-TAB1 phosphorylation and binds polyubiquitin to direct signaling to NF-kappaB" J. Biol. Chem 283(28): 19245-19254. PMCID:PMC2443674

Wang, W., Chronmiller, C., and Brautigan, D. L.  (2008) "Phosphatase inhibitor-2 is a maternal gene required for mitotic synchrony in Drosophila embryogenesis" Genetics. 179(4): 1823-33. PMCID:PMC2516061 

Smith, S.C. Oxford, G., Baras, A.S., Owens, C., Havaleshko, D., Brautigan, D.L., Safo, M.K., Theodorescu, D. (2007) "Expression of Ral GTPases, Their Effectors, and Activators in Human Bladder Cancer" Clin. Cancer Res. 13(13): 3803-3813 PMID:17606711

Eto, M., Kitazawa. T., Matsuzawa, F., Aikawa, S., Kirkbride, J. A., Isozumi, N., Nishimura, Y., Brautigan, D. L., and Ohki, S. (2007) Phosphorylation-induced conformational switching of CPI-17 produces a potent myosin phosphatase inhibitor. Structure, 15(12): 1591-1602.  PMCID:PMC2217667.

Guo, C. Mi, J., Brautigan, D.L. and Larner, J.M. (2007) "ATM Regulates Ionizing Radiation-induced Disruption of HDAC1:PP1:Rb Complexes" Cellular Signalling 19(3): 504-510 PMID:17008050.

Mi, J., Guo, C. Brautigan, D. L. and Larner, J. M. (2007)  "Protein phosphatase-1 alpha Regulates Centrosome Separation and Duplication through Nek2A"  Cancer Res. 67: 1082-1089. PMID 17283141.

Li, M., Satinover, D.L. and  D. L. Brautigan (2007) "Phosphorylation and Functions of Family of Inhibitor-2" Biochemistry (ACS) 46: 2380-2389 PMID 17286390

Yoo, S. J.-S., Boylan, J. M., Brautigan, D. L. and P. A. Gruppuso  (2007) Subunit Composition and Developmental Regulation of Hepatic Protein Phosphatase 2A (PP2A) Arch. Biochem. Biophys. 461(2):186-193 PMCID:PMC1868455 doi:10.1016/j.abb.2007.02.019

Yang, C-S., Xin, H-W., Kelley, J. B., Spencer, A., Brautigan, D.L., and Paschal, B. M. (2007) "Ligand binding to the androgen receptor induces conformational changes that regulate phosphatase interactions." Mol. Cell. Biol. 27: 3390-3404 PMCID:PMC1899975.

Eto, M., Kirkbride, J., Elliott, E., Lo, S.H., and Brautigan, D. L. (2007) Association of the tensin PTP domain with alpha isoform of protein phosphatase-1 in focal adhesions." J. Biol. Chem 282: 17806-17815 on-line 15 April, PMID 17435217.

Prickett, T.D. and D. L. Brautigan (2007) "Cytokine activation of p38MAPK and apoptosis is opposed by alpha-4 targeting of PP2A for site-specific dephosphorylation of MEK3" Mol. Cell. Biol. 27: 4217-4227 PMCID:PMC1900036.

Stefansson, B., and Brautigan, D.L. (2007) Protein Phosphatase PP6 N terminal Domain Restricts G1 to S Phase Progression in Human Cancer Cells. Cell Cycle 6: 1386-1392 PMID:17568194.

last update June 2012