Laboratory Specialist I - 0617458

The Department of Neuroscience at the University of Virginia seeks a Laboratory Specialist to work in the laboratory of Dr. Alban Gaultier. This position entails providing assistance with laboratory oversight and experimental procedures. Duties will include animal handling, isolation and culture of primary cells, tissue culture, performing biochemistry and molecular biology assays, ordering supplies, maintaining laboratory equipment, and the training and overseeing of undergraduate students.

A Bachelor's degree in Biology, Microbiology, Biochemistry, Neuroscience, or a related field and at least two years of lab experience (student experience may be accepted) is required. A strong background in primary cell isolation and tissue culture is desired.

This position is restricted and dependent on the continuation of funding.


Laboratory Technician I - 0617373

The Department of Neurology at the University of Virginia is seeking a Laboratory Technician 1. The position carries out research studies and assists in experiments for the laboratory of Dr. J. Javier Provencio, MD. The role of this position is to perform and assist with experiments involving innate inflammation in the setting of brain aneurysm rupture, in particular neutrophil and monocyte trafficking into the brain after subarachnoid hemorrhage. including the use of using animal models. Responsibilities include working with small animals, laboratory procedures, assisting with collection and entry of data in electronic media and laboratory maintenance.

Qualified applicants must have a Bachelor's degree in Biology, Chemistry, Molecular Biology, Biochemistry or a related field, and some experience working actively in a research laboratory. Experience as a student may be considered. Experience in standard molecular biology procedures preferred.

In addition, candidates must be able to perform routine laboratory data analysis and procedures; independently prepare solutions and reagents; perform or learn to work with animal models; resolve problems and work accurately and with attention to detail. Must have ability to analyze and organize work procedures; plan and execute tasks or experiments; and interpret and report findings. Proficiency in Microsoft Word, PowerPoint and Excel is required. Additional expertise in statistical and data analysis software, database software, modeling software, and imaging and/or image analysis software is a plus.


Computational Biologist - 0617372

The Center for Brain Immunology and Glia in the Department of Neuroscience at the University of Virginia is seeking a Computational Biologist/Bioinformatics Analyst with a background in biology/immunology/neuroscience to collaborate with investigators within the center and to work closely with the bioinformatics core within the School of Medicine.

The incumbent will manage and analyze large-scale datasets produced by next-generation sequencing. The analyst will identify opportunities and implement solutions for managing, visualizing, analyzing, and interpreting genomic data, including studies of gene expression (RNA-seq and microarrays), pathway analysis, protein-DNA binding (e.g. ChIP-seq), DNA methylation, and DNA variation. The analyst will work closely with the center director to assist in experimental design and provide expert consultation, technical, and scientific support for investigators, and assist in outreach and training activities. The analyst will organize large-scale gene expression and sequencing data sets, manipulate and format data with perl, python, or other scripting languages, use established software to assess quality and analyzes data, schedule and run jobs on a high-performance computing cluster, use Unix and/or a scripting language to extract meaningful results from output, use software or genome browsers for visualization, and implement custom data management and analysis solutions as necessary. The candidate will assume lead roles in research projects by supervising students and post-doctoral fellows and developing innovative approaches for data analysis. The candidate is also encouraged to develop an independent research program and seek external funding.

Qualified candidates must have a PhD with three or more years of experience in Bioinformatics analysis, Computational Biology, Biostatistics, Neuroscience, Immunology, or a related field. Candidates with a Masters degree and five years of experience will be considered in lieu of a PhD.

Proficiency in R/Bioconductor and Python and a background in computer programming are required. A background in "omics" is desired, including transcriptomics, proteomics, or metabolomics. Successful candidates must have a demonstrated ability to translate biological questions into technical designs.

This position is restricted and contingent on the continuation of funding.


Research Associate - 0617374

The Harris Laboratory in the Department of Neuroscience at the University of Virginia is seeking a Postdoctoral Research Associate. The successful candidate will perform research in the field of immune regulation during CNS infection. The laboratory aims to elucidate the mechanisms by which regulatory T cells function in the CNS in order to limit immune-mediated pathology. The laboratory utilizes multiphoton microscopy, flow cytometry, immunohistochemistry, among other techniques to understand how immune cells function in immune-privileged tissues. The successful candidate will join the Center for Brain Immunology and Glia at the University of Virginia, which provides access to state-of-the-art microscopy and flow cytometry facilities.

Qualified candidates must have an M.D. and/or a Ph.D. in Immunology, Microbiology, Neuroscience, or a related field in hand by start date, and must have at least one publication in a peer-reviewed journal. Extensive experience with flow cytometry (8 color or more) or confocal microscopy and a basic knowledge of cellular immunology techniques is required. The ability to work independently, yet also interact well with a diverse group of scientists and students is essential.

For further information about the position, please contact Tajie H. Harris, PhD via email at thh9t@Virginia.EDU or via telephone at 434-982-6916. Applicant review will begin October 2, 2015, and the position will remain open until filled.


Research Associate - 0616752

A Postdoctoral Research Associate position is available in the Kipnis Lab in the Department of Neuroscience at the University of Virginia to study immune cells in healthy and diseased CNS. Candidates will be expected to publish their findings and mentor students in the lab.

Candidates must have a Ph.D. in Neuroscience, Immunology or a related discipline and/or an M.D. by the start date. Experience with intravital microscopy is preferred. Passionate and motivated candidates who work well in a busy lab environment are encouraged to apply.


Research Associate - 0616813

The Department of Neuroscience at the University of Virginia seeks a Research Associate/postdoctoral fellow to work on the crosstalk between the gut microbiota and the central nervous system in the context of depression. Position is in the laboratories of Dr. Alban Gaultier and Dr. Jonathan Kipnis within the center for Brain Immunology and Glia (http://www.medicine.virginia.edu/research/institutes-and-programs/big/welcome-to-big).

Candidates must have a PhD or MD degree in hand by start date, and have a background in Neuroscience and/or Immunology, as well as extensive experience in conducting independent research, and supervising research trainees and/or technicians. In addition, the candidate must have first author publications in peer reviewed scientific journals and effective oral and written communication skills. Candidates with experience in microbiome research and animal models of depression are preferred.


Research Scientist - 0616556

The Department of Neuroscience of the University of Virginia seeks a Research Scientist to work in the Laboratory of Dr. Kevin S. Lee, Ph.D. The successful candidate is expected to perform assigned tasks on his/her own initiative. In addition to a firm background in the particular field, the Candidate should demonstrate the ability to assume leadership of small groups and work without additional supervision once objectives are defined and methods of approach set.

Candidates must have a doctoral degree or a master's degree with significant experience and experience training graduate students.


Research Scientist - 0617407

The Department of Neurology at the University of Virginia seeks a Postdoctoral Research Scientist to work in the laboratory of Dr. J. Javier Provencio, MD. The incumbent will conduct studies investigating innate inflammation in the setting of brain aneurysm rupture, in particular neutrophil and monocyte trafficking into the brain after subarachnoid hemorrhage. Additional duties will include writing and preparing manuscripts for scientific publication, participation in lab meetings, teaching other members of the lab, and active collaboration with other researchers.

Candidates must have an MD and/or PhD completed by the start date, 3+ years of post doctoral research experience and publications in peer-reviewed journals. The candidate must have demonstrated expertise in animal models of disease, biochemistry, cell biology, molecular biology, immunology, and cell culture.

The Candidates must work independently and ethically, to document all research data applicable, and publish data in qualified journals. Excellent written and verbal communication skills are required. The candidates should demonstrate potential to be trained as an independent investigator.

The position will remain open until filled. For further information please contact Greg Haskins at gph3z@virginia.edu.