Tung Laboratory Selected Publications

2009:

· Guth, A et al.  Spontaneous autoimmunity in mice that carry an IgHV partial transgene: A required arginine in VHCDR3.  Lupus.  in press.  (2009)   PubMed Link

· Wheeler, K et al.  Antigen-specific regulatory T cells in normal regional lymph nodes maintain peripheral tolerance.  J Immunol. in revision  (2009)   PubMed Link

2008:

· Chevali, AK et al.  Characterizing emergent properties of immunological systems with multi-cellular rule-based computational modeling.  Trends Immunol.  29(12),  589-99  (2008)   PubMed Link  

· Samy, ET et al.  Cutting edge: Autoimmune disease in day 3 thymectomized mice is actively controlled by endogenous disease-specific regulatory T cells.  J Immunol.  180(7),  4366-70  (2008)   PubMed Link

2007:

· Li, YS et al.  Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus.  J Immunol.  178(3),  1938-47  (2007)   PubMed Link   

2006:

· Samy, ET et al.  The role of physiological self-antigen in the acquisition and maintenance of regulatory T-cell function.  Immunol Rev. 212,  170-84  (2006)   PubMed Link

· Setiady, YY et al.  Physiologic self antigens rapidly capacitate autoimmune disease-specific polyclonal CD4+ CD25+ regulatory T Cells.  Blood.  107(3),  1056-62  (2006)   PubMed Link

2005:

· Samy, ET et al.  Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph node.  J Exp Med.  202(6),  771-81  (2005)   PubMed Link

2004:

· Setiady, YY et al.  Requirements of NK cells and proinflammatory cytokines in T cell-dependent neonatal autoimmune ovarian disease triggered by immune complex.  J Immunol.  173(2),  1051-8  (2004)   PubMed Link

· Waters, ST et al.  Breaking tolerance to double stranded DNA, nucleosome, and other nuclear antigens is not required for the pathogenesis of lupus glomerulonephritis.  J Exp Med.  199(2),  255-64  (2004)   PubMed Link

2003:

· Roper, RJ et al.  Aod1 controlling day 3 thymectomy-induced autoimmune ovarian dysgenesis in mice encompasses two linked quantitative trait loci with opposing allelic effects on disease susceptibility.  J Immunol.  170(12),  5886-91  (2003)   PubMed Link

· Seiady, YY et al.  Maternal autoantibody triggers de novo T cell-mediated neonatal autoimmune disease.  J Immunol.  170(9),  4656-64  (2003)   PubMed Link

· Sharp, C et al.  CD40 ligand in pathogenesis of autoimmune ovarian disease of day 3-thymectomized mice: implication for CD40 ligand antibody therapy.  J Immunol.  170(4),  1667-74  (2003)   PubMed Link

2001:

· Tung, KS et al.  Regulatory T-cell, endogenous antigen and neonatal environment in the prevention and induction of autoimmune disease.  182,  135-48  (2001)   PubMed Link

· Waters, ST et al.  NZM2328: a new mouse model of systemic lupus erythematosus with unique genetic susceptibility loci.  Clin Immunol.  100(3),  372-83  (2001)   PubMed Link

· Agersborg, SS et al. Intestinal parasitism terminates self tolerance and enhances neonatal induction of autoimmune disease and memory.  Eur J Immunol  31(3),  851-9  (2001)   PubMed Link

· Alard, P et al.  Endogenous oocyte antigens are required for rapid induction and progression of autoimmune ovarian disease following day-3 thymectomy.  J Immunol.  166(7),  4363-9  (2001)   PubMed Link

2000:

· Garza, KM et al.  Persistence of physiological self antigen is required for the regulation of self tolerance.  J Immunol.  164(8),  3982-9  (2000)   PubMed Link

· Lou, YH et al.  Retargetting T cell-mediated inflammation: a new perspective on autoantibody action.  J Immunol.  164(10),  5251-7  (2000)   PubMed Link

PubMed complete list of publications