Cre Flox Flp Mice

Cre Flox Flp Mice

Cre/Flox/Flp Mice on Grounds

 

Strain Background Promoter/Exp. Original Source
Lab

(1) Widespread/germline deleter

Tg(EIIa-Cre)C5379Lmgd/J B6.FVB EIIa Jax 003724 David Wotton
Tg(MMTV-Cre)4Mam/J B6129F1 MMTV Jax 003553 Tom Parsons
Hsp70-Cre Hsp70 Scott Zeitlin

(2) Inducible

Tg(Mx1-cre)1Cgn/J B6.Cg Mx1 (plpC or interferon) Jax 003556 Adam Goldfarb
Tg(Cre/Esr1)5Amc/J B6.Cg CMV(tamoxifen) Jax 004682 Gary Owens Xiaowei Lu Jing Yu
Tg(Sp7-tTA,tetO- EGFP/Cre)1Amc/J B6.Cg Sp7 (Dox), "Tet-Off", osteoblast Jax 006361 Greg Clines
Tg(Atoh1-CreER-IRES-AP)1Sbk FVB Atonal homolog 1 (tamoxifen) MMRRC 029581-UNC Xiaowei Lu

(3) Knock-in

CD19-Cre B6, B6;129, 129 CD19 Jax 004126 Tim Bender
Mb1-Cre B6;129;BALB/c Mb1 Tim Bender
Th<tm1(Cre)Te/Kieg> B6.129X1 Tyrosine hydroxylase EMMA 00254 Ruth Stornetta
Chat<tm1(Cre)Lowl>/J B6;129S6 Choline acetyltransferase Jax 006410 Ruth Stornetta
Foxg1tm1(cre)Skm/J 129.Cg Foxhead box g1 Jax 004337 Xiaowei Lu

(4) Tissue/cell specific

SMHC-Cre Smooth myosin heavy chain Gary Owens
SM22-Cre Smooth muscle 22 Gary Owens
SMHC-Cre/EGFP Smooth myosin heavy chain Gary Owens
Col a1(I)2.3 Cre FVB Collagen 1a1 Greg Clines
TgN(MCK-Cre) B6.FVB Muscle creatine kinase Thurl Harris
Tg(Fabp4-Cre)1Rev/J B6.Cg Fatty acid binding protein 4 Jax 005069 Thurl Harris
CD21-Cre3a B6.Cg immature mIgM+ mIgD- bone marrow cells Jax 006368 Tim Bender
Lck-Cre B6;129 T-lineage cells Tim Bender
CD4-Cre B6;129 DN4 and DP thymocytes Tim Bender
Distal lck-Cre B6;DBAs SP thymocytes Tim Bender
IgG alpha-Cre B cell Tom Parsons
LysM-Cre Macrophage Tom Parsons
Tg(Alb-Cre) B6.Cg Albumin Jax 003574 David Wotton
Math1-Cre Atonal homolog 1 Xiaowei Lu
Tg(Pax2-cre)1Akg CD-1 Pax2 MMRRC 010560-UNC Xiaowei Lu
Wnt1-Cre, R26R Wnt1a Roy Olge
Nestin-Cre Rat nestin Jeh-Ping Liu
Isl1-Cre Isl1 txn factor Jeh-Ping Liu
HB9-Cre Motor neuron Jeh-Ping Liu
CaMKII-Cre (R1, L7, R4) Ca/Cal kinase II Scott Zeitlin
Tg(Sox2-Cre)1Amc/J B6CBA SRY-box containing gene 2 Jax 004783 David Wotton
SP10-Cre Spermatid Prabu Reddi
Tg(Pbsn-Cre)4Prb B6.D2 Rat probasin NCI 01XF5 Tom Parsons

(5) Flox

RUNX1 Adam Goldfarb
KLF4 Gary Owens
TGFβ Gary Owens
PDGF β receptor Gary Owens
PDGF β chain Gary Owens
TGIF David Wotton
ETAR B6;129 Endothelin A receptor Greg Clines
Mybf/f (c-Myb) B6, B6;129 Exon II Tim Bender
Mybl2f/f (B-Myb) B6;129 Exon II-IV Tim Bender
Rictor Thurl Harris
Hoxc8 Jeh-Ping Liu
Hoxc6 Jeh-Ping Liu
Gt(ROSA)26Sortm1Sor/J 129S

LoxP-STOP-LoxP-LacZ

Jax 003310 Tom Parsons Gary Owens Roy Ogle
Gt(ROSA)26Sortm1(EYFP)/Cos/J B6 LoxP-STOP-LoxP-EYFP Jax 006148 Tom Parsons
Gt(ROSA)26Sortm1(Luc)Kael/J FVB.129S6(B6) LoxP-STOP-LoxP-Luciferase Jax 005125
Id3 B6-Cg floxed Coleen McNamara

(6) Flp

Tg(ACTFLPe)9205Dym/J B6.Cg Human β-actin Jax 005703 Xiaowei Lu
Tg(CAG-FLPo)1Afst/Mmucd C57BL/6N Codon-optimized FLP MMRRC 036512-UCD Ariel Gomez
Tg(PGK1-FLPo)10Sykr/J B6(C3) Codon-optimized FLP Jax 011065 Kevin Lynch
Gt(Rosa)26Sortm1(FLP1)Dym/RainJ B6.129S4 KI Jax 009086
(7)Tg/KO Mice
FVB-Tg(Pbsn-AKT1)9Wrs FVB Probasin-AKT1 NCI 01XJ7 Bryce Paschel
Rho GDI alpha 50% 129SV, 25% DBA2, 25% C57BL/6 KO Jun Miyoshi Dan Theodorescu
Rho GDI beta 50% 129SV, 25% DBA2, 25% C57BL/6 KO Jun Miyoshi Dan Theodorescu

B6.129P2-Apoetm1Unc/J

B6.129 KO

Jax 002052

Coleen McNamara

B6.129S-Id3tm1Zhu/J

B6.129 KO

Jax 006301

Coleen McNamara