Poster illustrating work of DNA science program

Poster showing work in Mass Spectrometry program.

Current methodology for identification of phosphorylation sites

Introduction to how mass spectrometers analyze proteins

Papers-mass spectrometry

Chianese-Bullock KA. Lewis ST. Sherman NE. Shannon JD. Slingluff CL Jr. Multi-peptide vaccines vialed as peptide mixtures can be stable reagents for use in peptide-based immune therapies. Vaccine. 27(11):1764-70, 2009

Tao J. Hu K. Chang Q. Wu H. Sherman NE. Martinowich K. Klose RJ. Schanen C. Jaenisch R. Wang W. Sun YE. Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function. Proceedings of the National Academy of Sciences of the United States of America. 106(12):4882-7, 2009

Boettner DR. Huston CD. Linford AS. Buss SN. Houpt E. Sherman NE. Petri WA Jr. Entamoeba histolytica phagocytosis of human erythrocytes involves PATMK, a member of the transmembrane kinase family. [Journal Article. Research Support, N.I.H., Extramural] PLoS Pathogens. 4(1):e8, 2008

Mayhew MW. Jeffery ED. Sherman NE. Nelson K. Polefrone JM. Pratt SJ. Shabanowitz J. Parsons JT. Fox JW. Hunt DF. Horwitz AF. Identification of phosphorylation sites in betaPIX and PAK1.  Journal of Cell Science. 120(Pt 22):3911-3918, 2007.

Goldfinger LE. Ptak C. Jeffery ED. Shabanowitz J. Han J. Haling JR. Sherman NE. Fox JW. Hunt DF. Ginsberg MH. An experimentally derived database of candidate Ras-interacting proteins. [Journal Article. Research Support, N.I.H., Extramural. Research Support, Non-U.S. Gov't] Journal of Proteome Research. 6(5):1806-11, 2007 May.

Abbas T. Jha S. Sherman NE. Dutta A. Autocatalytic phosphorylation of CDK2 at the activating Thr160. Cell Cycle. 6(7):843-52, 2007

Dorrello NV. Peschiaroli A. Guardavaccaro D. Colburn NH. Sherman NE. Pagano M. S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth Science 314(5798):467-71, 2006

Background papers-mass spectrometry

Mandal, A., Naaby-Hansen, S., Wolkowicz, M.J., Klotz, K., Shetty, J., Retief, J.D., Coonrod, S.A., Kinter, M., Sherman, N., Cesar, F., Flickinger, C.J. and Herr, J.C. (1999) Biol. Reprod. 61 1184-1197

S.L. Hanna, N.E. Sherman, M.T. Kinter, J.B. Goldberg (2000) Microbiology 146 2495-2508

Protein Sequencing and Identification Using Tandem Mass Spectrometry M. Kinter and N.E. Sherman (Wiley InterScience, 2000) (Health Sciences library catalog QP551 .K495 2000 )

Shared Instrumentation

Sullivan JT. Jeffery EF. Shannon JD. Ramakrishnan G. Characterization of the siderophore of Francisella tularensis and role of fslA in siderophore production. [Journal Article. Research Support, N.I.H., Extramural] Journal of Bacteriology. 188(11):3785-95, 2006 Jun.