Tissue Adhesive Publications from William D. Spotnitz, M.D.

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Tissue Adhesive Publications from William D. Spotnitz, M.D.


(last updated 3/4/11)

PUBLICATIONS AND/OR MATERIALS REFERENCED ARE NOT ENDORSED BY THE UNIVERSITY OF VIRGINIA; RATHER, THESE ARE SIMPLY REFERENCES TO MATERIALS THAT MAY BE OF INTEREST ON THE TOPIC OF TISSUE ADHESIVES.

PUBLISHED ARTICLES:

  1. Glover W, Chavis TV, Daniel TM, Kron IL, Spotnitz WD. Fibrin glue application via the flexible fiberoptic bronchoscope: Closure of bronchopleural fistulas. J Thorac Cardiovasc Surg 93:470-472, 1987.
  2. Baker JW, Spotnitz WD, Nolan SP. A technique for spray application of fibrin glue during cardiac operations. Ann Thorac Surg 43:564-565, 1987.
  3. Spotnitz WD, Mintz PD, Avery N, Bithell TC, Kaul S, Nolan SP. Fibrin glue from stored human plasma: An inexpensive and efficient method for local blood bank preparation. Am Surg 53:460-464, 1987.
  4. Spotnitz WD, Dalton MS, Baker JW, Nolan SP. Reduction of perioperative hemorrhage by anterior mediastinal spray application of fibrin glue during cardiac operations. Ann Thorac Surg 44:529-531, 1987.
  5. Lindsey WH, Spotnitz WD, Llaneras MR, Masterson TM, Wanebo HJ, Morgan RF. Seroma prevention using fibrin glue during modified radical neck dissection in a rat model. Am J Surg 156:310-313, 1988.
  6. Stuart JD, Kenney JG, Spotnitz WD, Baker JW, Lettieri J. Application of single donor fibrin glue to burns. J Burn Care & Rehab 9:619-622, 1988.
  7. Spotnitz WD, Dalton MS, Baker JW, Nolan SP. Successful use of fibrin glue during two years of surgery at a university medical center 1985-1987. Am Surg 55:166-168, 1989.
  8. Baker JW, Spotnitz WD, Matthew TL, Fechner RE, Nolan SP. Mediastinal fibrin glue: hemostatic effect and tissue response in calves. Ann Thorac Surg 47:450-452, 1989.
  9. Ishitani MB, McGahren ED, Sibley DA, Spotnitz WD, Rodgers BM. Laparoscopically applied fibrin glue in experimental liver trauma. J Pediatr Surg 24:867-871, 1989.
  10. Valenzuela GA, Spotnitz WD, Stone DD. Pepsin fibrinolysis of fibrin glue. Surgical Endoscopy 3:148-151, 1989.
  11. Shaffrey, CI, Spotnitz WD, Shaffrey ME, Jane JA. Neurosurgical applications of fibrin glue: Augmentation of dural closure in 134 patients. Neurosurgery 26:207-210, 1990.
  12. Lindsey WH, Masterson T, Spotnitz WD, Wilhelm MC, Morgan RF. Seroma prevention using fibrin glue in a rat mastectomy model. Arch Surg 125:305-307, 1990.
  13. Matthew TL, Spotnitz WD, Kron IL, Daniel TM, Tribble CG, Nolan SP. Four years experience with fibrin sealant in thoracic and cardiovascular surgery. Ann Thorac Surg 50:40-44, 1990.
  14. Matthew TL, Spotnitz WD, Gonias SL, Abbott RD, Jane JA. Increasing the life span of fibrin sealant-a comparison of three antifibrinolytic agents. Surg Forum XLI :504-506, 1990.
  15. Pipan CM, Glasheen WP, Gonias SL, Jane JA, Spotnitz WD. The life span of intraperitoneal fibrin sealant: the effects of three antifibrinolytic agents. Surg Forum XLII:519-21, 1991.
  16. Pipan CM, Glasheen WP, Matthew TL, Gonias SL, Hwang L-J, Jane JA, Spotnitz WD. The effects of antifibrinolytic agents on the life span of fibrin sealant. J Surg Res 53:402-407, 1992.
  17. Ismail S, Glasheen WP, Gonias SL, Jane JA, Spotnitz WD. Bovine fibrin sealant: the intraperitoneal life span of a new hemostatic agent. Surg Forum XLIV:572-574, 1993.
  18. Ismail S, Combs, MJ, Goodman NC, Teotia SS, Teates CD, Abbott RD, Fechner RE, Nolan SP, Powers ER, Spotnitz WD. Reduction of femoral arterial bleeding post catheterization using percutaneous application of fibrin sealant. Cath Cardiovasc Diag 34:88-95, 1995.
  19. Spotnitz WD. Fibrin sealant in the United States: Clinical use at the University of Virginia. Thromb Haemost 74:482-485, 1995.
  20. Sanders RP, Goodman NC, Amiss Jr LR, Pierce RA, Moore MM, Marx G, Morgan RF, Spotnitz WD. Effect of fibrinogen and thrombin concentrations on mastectomy seroma prevention. J Surg Res 61:65-70, 1996.
  21. Wang JY, Goodman NC, Amiss LR Jr, Nguyen DHD, Rodeheaver GT, Moore MM, Morgan RF, Abbott RD, Spotnitz WD. Seroma prevention in a rat mastectomy model: use of a light-activated fibrin sealant. Ann Plast Surg 37:400-405, 1996.
  22. Moore MM, Nguyen DHD, Spotnitz WD. Fibrin sealant reduces serous drainage and allows earlier drain removal after axillary dissection: a randomized prospective trial. Am Surg 63:97-102, 1997.
  23. Falstrom JK, Goodman NC, Ates G, Abbott RD, Powers ER, Spotnitz WD. Reduction of femoral artery bleeding post catheterization using a fibrin enhanced collagen sealant. Cath Cardiovasc Diag 41:79-84, 1997.
  24. Martinowitz, U, Spotnitz, WD. Fibrin tissue adhesives. Thromb Haemost 78: 661-666, 1997.
  25. Curtin W, Wang G-J, Goodman N, Abbott R, Spotnitz W. Reduction of bleeding using cryo-based fibrin sealant in a canine anticoagulated knee arthroplasty model. Surg Forum XLVIII: 558-560, 1997.
  26. Moore M, Burak Jr. W, Nelson E, Kearney T, Simmons R, Buchanan S, Spotnitz WD. Fibrin sealant reduces the amount and duration of fluid drainage after axillary lymphadenectomy. Surg Forum XLVIII: 866-867, 1997.
  27. Spotnitz WD. New developments in the use of fibrin sealant: a surgeon's perspective. J Long-Term Eff Med Implants, 7: 243-253, 1997.
  28. Spotnitz WD. Four years' experience with fibrin sealant in thoracic and cardiovascular surgery: an update. Ann Thorac Surg 65: 592-3, 1998.
  29. Marek CA, Amiss Jr LR, Morgan RF, Spotnitz WD, Drake DB. Acute thrombogenic effects of fibrin sealant on microvascular anastomoses in a rat model. Ann Plast Surg 41: 415-419, 1998.
  30. Falstrom JK, Moore MM, Caldwell SH, Matsumoto AH, Abbott RD, Spotnitz WD. Use of fibrin sealant to reduce bleeding after needle liver biopsy in an anticoagulated canine model: work in progress. JVIR 10:457-462, 1999.
  31. Curtin WA, Wang GJ, Goodman NC, Abbott RD, Spotnitz WD. Reduction of hemorrhage after knee arthroplasty using cryo-based fibrin sealant. J Arthroplasty 14:481-487, 1999.
  32. Wang J, Neisely H, Moody D, Dobraz J, Spotnitz WD, Rodeheaver GT. Fibrin sealant delivery system increases the effectiveness of silver sulfadiazine. Surg Forum L:624-626, 1999.
  33. Tholpady SS, Schlosser RJ, Spotnitz WD, Ogle RC, Lindsey WH. Repair of an osseous facial critica-size defect using augmented fibrin sealant. Laryngoscope 109:1585-1588
  34. O'Neill PJ, Flanagan HL, Mauney MC, Lantrip BS, Wallace KK, Spotnitz WD, Daniel TM. Intrathoracic Catheter-Directed Fibrin Sealant Application Using Computed Tomography Fluoroscopy. Ann Thorac Surg 70:301-302, 2000
  35. Schlosser RJ, Spotnitz WD, Rodeheaver G, Scheld WM, Iezzoni J, Gross CW. Effects of fibrin sealant-containing antibiotics in rabbit model of chronic sinusitis. Am J Rhinology 14:233-240, 2000.
  36. Drake DB, Faulkner BC, Amiss Jr LR, Spotnitz WD, Morgan RF. Thrombogenic effects of a nonthrombin-based fibrin sealant compared with a thrombin-based fibrin sealant in microvenous anastomoses in a rat model. Ann Plat Surg 45:520-524, 2000
  37. Schlosser RJ, Gallagher R, Burks SG, Flanagan HL, Mintz PD, Avery NL, Mayers SL, Spotnitz WD, Gross CW. Autologous fibrin sealant reduces pain after tonsillectomy. Laryngoscope 111:259-263, 2001
  38. Mintz PD, Mayers L, Avery N, Flanagan HL, Burks SG, Spotnitz WD. Review: Fibrin Sealant: Clinical Use and the Development of the University of Virginia Tissue Adhesive Center. Ann Clinical & Laboratory Science 31:108-118, 2001
  39. Frost-Arner L, Spotnitz WD, Rodeheaver GT, Drake DB. Comparison of the thrombogenicity of internationally available fibrin sealants in an established microsurgical model. J Plastic Reconstruct Surg, 108:1655-1660, 2001.
  40. Moore MM, Burak Jr W, Nelson E, Kearney T, Simmons R, Mayers SL, Spotnitz WD. Fibrin sealant reduces the duration and amount of fluid drainage following axillary dissection: a randomized prospective clinical trial. J Am Coll Surg, 192:591-599, 2001
  41. Wang GJ, Hungerfort DS, Savory CG, Rosenberg AG, Mont MA, Burks SG, Mayers SL, Spotnitz WD. Use of fibrin sealant to reduce bloody drainage and hemoglobin loss after total knee arthroplasty. A brief note of a randomized prospective trial. J Bone and Joint Surg, 83-A:1503-1505, 2001.
  42. Frost-Arner L, Spotnitz WD, Rodeheaver GT, Drake DB.  Comparison of the thrombogenicity of internationally available fibrin sealants in an established microsurgical model.  J Plastic Reconstruct Surg 108:1655-1660, 2001.
  43. Schenk W, Goldthwaite Jr C, Burks S, Spotnitz W.  Fibrin sealant facilitates hemostasis in arteriovenous polytetrafluoroethylene grafts for renal dialysis access. Am Surg 68:728-732, 2002.
  44. Schenk W, Burks S, Gagne P, Kagan S, Lawson J, Spotnitz W.   Fibrin sealant improves hemostasis in peripheral vascular surgery: a randomized prospective trial.  Annals of Surgery 237: 871-876, 2003.
  45. Wang GJ, Goldthwaite Jr. CA, Burks SG, Spotnitz WD.   Experience improves successful use of fibrin sealant in total knee arthroplasty: implications for surgical education.   J Long-Term Effects Medical Implants 13:389-397, 2003.
  46. Wang GJ, Goldthwaite Jr. CA, Burks SG, Crawford R, Spotnitz WD.   Fibrin sealant reduces perioperative blood loss in total hip replacement.   J Long-Term Effects Medical Implants 13: 399-411, 2003.
  47. Spotnitz WD, Prabhu R. Fibrin sealant tissue adhesive - a review and an update. J Long-Term Effects of Medical Implants 15: 245-270, 2005.
  48. Schenk WG, Spotnitz WD, Burks SG, Lin PH, Bush RL, Lumsden AB. Absorbable cyanoacrylate as a vascular hemostatic sealant: a preliminary trial. Am Surg 71:658-661, 2005.
  49. Benjamin RJ, McCullough J, Mintz PD, Snyder E, Spotnitz WD, Rizzo RJ, Wages D, Lin JS, Wood L, Corash L, Conlan MG. Therapeutic efficacy and safety of red blood cells treated with a chemical process (S-303) for pathogen inactivation: a Phase III clinical trial in cardiac surgery patients. Transfusion 45:1739-49, 2005.
  50. Spotnitz WD. Active and Mechanical Hemostatic Agents. Surgery 142: S34-S38, 2007.
  51. Spotnitz WD, Burks S.  hemostats, sealants, and adhesives: Components of the surgical toolbox.  Transfusion 48:1502-1516, 2008.
  52. Spotnitz WD. Fibrin sealant: past, present, and future: a brief review. World J Surg 34: 632-34, 2010.
  53. Spotnitz WD, Burks S. State-of-the-art review: hemostats, sealants, and adhesives II: update as well as how and when to use the components of the surgical toolbox. Clinical and Applied Thrombosis/Hemostasis 16:497-514, 2010.

PUBLISHED ABSTRACTS:

  1. Spotnitz WD, Surgical applications of fibrin glue. Virg Med 113:230-231, 1986.
  2. Valenzuela GA, Spotnitz WD, Stone DD. Effect of pepsin, pH, and E-amino-caproic acid on fibrin glue survival. Am J Gastro 82:930(a), 1987.
  3. Matthew TL, Spotnitz WD, Daniel TM, Kron IL. Closure of small bronchopleural fistulas using fibrin sealant through the flexible fiberoptic bronchoscope. Chest 94:77S, 1988.
  4. Wang J, Goodman NC, Amiss, Jr. LR, Nguyen DHD, Rodeheaver GT, Moore MM, Morgan RF, Spotnitz WD. Seroma prevention in a rat mastectomy model: use of a light activated fibrin sealant. J Assoc Acad Minority Physicians 6:147, 1995.
  5. Falstrom JK, Goodman NC, Moore MM, Caldwell SH, Abbott RD, Spotnitz WD. Reduction of bleeding from liver biopsy using fibrin sealant. Virginia Med Quart 124:120, 1997.
  6. Moore MM, Nguyen D, Slingluff CL, Hanks J, Spotnitz WD. Fibrin sealant reduces serous drainage and allows for earlier drain removal after axillary dissection for early stage breast cancer: a randomized prospective trial. Thromb Haemost Supplement 177, 1997.
  7. Falstrom JK, Goodman NC, Ates G, Abbott RD, Powers ER, Spotnitz WD. Reduction of femoral artery bleeding post catheterization using a collagen enhanced fibrin sealant. Thromb Haemost Supplement 252, 1997.
  8. Falstrom JK, Goodman NC, Moore MM, Caldwell SH, Abbott RD, Spotnitz WD. The use of fibrin sealant as a hemostatic plug for liver biopsy tracts. Thromb Haemost Supplement 197, 1997.
  9. Flanagan H, Mintz P, Burks S, Avery N, Spotnitz WD. Commercial and blood bank produced fibrin sealant: The changing clinical environment. Transfusion 39:146S, 1999.
  10. Flanagan H, Mintz P, Burks S, Avery N, Spotnitz WD. The development of a tissue adhesive center and its collaboration with a hospital blood bank. Transfusion 39:147S, 1999.
  11. Monson C, Robson T, Foresman P, Burks S, Wang J, Spotnitz W, Rodeheaver G.    Extended efficacy of silver sulfadiazine using fibrin sealant as a delivery matrix.  J Burn Care Rehab 23 (Suppl): S-115, 2002.

BOOK CHAPTERS:

  1. Spotnitz WD. History of tissue adhesives. In Sierra D, Saltz R (ed): Surgical Adhesives and Sealants, Current Technology and Applications. Technomic, 3-11, 1996.
  2. Spotnitz WD. Clinical applications of fibrin sealant in thoracic and cardiovascular surgery. In Sierra D, Saltz R (ed): Surgical Adhesives and Sealants, Current Technology and Applications. Technomic, 239-244, 1996.
  3. Bayfield MS, Spotnitz WD. Fibrin sealant in thoracic surgery, pulmonary applications, including management of bronchopleural fistula. In Miller J (ed): Chest Surgical Clinics of North America-Empyema, Spaces, and Fistula. WB Saunders 6:567-583, 1996.
  4.  Spotnitz WD, Falstrom JK, Rodeheaver GT. The role of sutures and fibrin sealant in wound healing. In Barbul A (ed): Surgical Clinics of North America - Wound Healing. WB Saunders 77:1-19, 1997.
  5. Spotnitz WD. Guest editorial commentary: The future of surgical tissue adhesives. In Bruck SD (ed): Journal of Long-Term Effects of Medical Implants- Topical Issue on Clinical Use of Fibrin Sealants and Other Tissue Adhesives Begell House 8: 81-85, 1998.
  6. Spotnitz WD, Welker RL. Clinical uses of fibrin sealant. In Mintz, PD (ed): Tranfusion Therapy: Clinical Principles and Practice AABB Press, 199-222, 1999.
  7. Spotnitz WD, Burks SG, Mercer DM. Clinical indications for surgical tissue adhesives. In Lewandrowski K-U, Wise DL, Trantolo DJ, Gresser JD, Yaszemski MJ, Altobelli DE (eds): Tissue Engineering and Biodegradable Equivalents: Scientific and Clinical Applications. Marcel Dekker, Inc. 2001(in press)
  8. Spotnitz WD, Mercer DM, Burks SG. Tissue adhesives and hemostats: New tools for the surgeon. In Reinhart TJ (ed): "Adhesives and their Applications." Elsevier Publishing Co., New York, New York, Vol. 3, 2001(in press) 
  9. Spotnitz WD, Burks S, Mercer D.  Clinical indications for surgical tissue adhesives.  In Lewandrowski K-U, Wise DL, Trantolo DJ, Gresser JD, Yaszemski MJ, Altobelli DE (eds): “Tissue Engineering and Biodegradable Equivalents: Scientific and Clinical Applications.”  Marcel Dekker, Inc., New York , New York , 32:651-664, 2002.
  10. Spotnitz WD, Mercer D, Burks S.   Tissue adhesives and hemostats: new tools for the surgeon.  In Chaudry M, Pocius AV (ed): “Adhesion Science and Engineering – 2:  Surfaces, Chemistry and Applications.”  Elsevier Science B.V., Amsterdam , The Netherlands , 1105-1128, 2002.
  11. Spotnitz WD, Burks S.  Use of tissue sealants in cardiac surgery.  In Franco KL and Verrier ED (eds): “Advanced Therapy in Cardiac Surgery” Second Edition, B.C. Decker, Inc., Hamilton, Ontario, Canada, 1-12, 2003. 
  12. Spotnitz WD, Burks SG. The tissue adhesive decision; algorithms for successful clinical use.   In Saltz R and Toriumi DM (eds): “Tissue Glues in Cosmetic Surgery.” Quality Medical, Inc, St. Louis , Missouri , 46-67, 2003.
  13. Spotnitz WD, Prabhu R, Welker R, Burks SG. Clinical uses of fibrin sealant. In Mintz PD (ed): “Transfusion Therapy: Clinical Principles and Practice.” Second Edition, AABB Press, Bethesda , Maryland , 437-477, 2004.
  14. Spotnitz WD, Prabhu R, Welker R, Burks SG. Clinical uses of fibrin sealant. In Mintz PD (ed): "Transfusion Therapy: Clinical Principles and Practice." Second Edition, AABB Press, Bethesda, Maryland, 437-477, 2004.
  15. Spotnitz WD, Burks SG, Prabhu R. Fibrin-based adhesives and hemostatic agents.  In Quinn JV (ed): "Tissue Adhesives in Clinical Medicine." BC Decker, Hamilton, Ontario, 77-112, 2005

  16. Spotnitz WD. Tissue adhesives: science, products and clinical use. In Pietrzak WS (ed): "Orthopedic Biology and Medicine: Musculoskeletal Tissue Regeneration, Biological Materials and Methods." Humana Press, Totowa, New Jersey, 531-546, 2008.

  17. Spotnitz WD. Topical hemostats. In Walters JH, Shander A, Gottschall JL (eds): "Perioperative Blood Management: A Physicians Handbook." 2nd Edition. AABB Press, Bethesda, Maryland, 2010.

  18. Spotnitz WD. Clinical uses of fibrin sealant-an update. In Mintz PD (ed): "Transfusion Therapy: Clinical Principles and Practice." Third Edition. AABB Press, Bethesda, Maryland, 2011.

EDITORIAL LETTERS:

  1. Spotnitz WD, Dalton MS, Baker JW, Nolan SP. Reply to the editor, reduction of perioperative hemorrhage by anterior mediastinal spray application of fibrin glue during cardiac operations. Ann Thorac Surg 46:254, 1988.
  2. Spotnitz WD. Introduction to special section on surgical tissue adhesives.  Surgical tissue adhesives:  new additions to the surgical armamentarium.  J Long Term Effects Medical Implants 13:385-387, 2003.