Christopher  M.  Kramer,  M.D.

Professor of Radiology, Radiology Research

B.A., Harvard University, 1982
M.D., University of California, San Francisco, 1986
Residency, Internal Medicine, University of Pennsylvania, 1989
Fellowship, Cardiology, University of Pennsylvania, 1993

University of Virginia Hospital Medical Center
Department of Radiology and Medical Imaging
Box 800170
Charlottesville, VA 22908

(434) 924-9391
ckramer@virginia.edu

Cardiovascular magnetic resonance imaging is a powerful technology that offers a comprehensive imaging approach to ischemic heart disease. A major focus of our work is on developing clinical applications of cardiovascular MRI. Active clinical protocols include developing a comprehensive MR exam for clinical trials in peripheral arterial disease including atherosclerotic plaque imaging and calf muscle perfusion and energetics at peak exercise. Other clinical studies include quantitative myocardial perfusion imaging, quantitative myocardial functional imaging as a measure of dyssynchrony in congestive heart failure, coronary artery and wall imaging, and imaging of left atrial structure and mechanics. Another focus of our research is on using cardiovascular MRI in a mouse model of myocardial infarction to understand the mechanisms underlying LV remodeling after myocardial infarction.

Myocardial Perfusion: Near-automated Evaluation from Contrast-enhanced MR Images Obtained at Rest and during Vasodilator Stress. Tarroni G, Corsi C, Antkowiak PF, Veronesi F, Kramer CM, Epstein FH, Walter J, Lamberti C, Lang RM, Mor-Avi V, Patel AR. Radiology. 2012 Aug 14. [Epub ahead of print]

Monocyte and/or macrophage infiltration of heart after myocardial infarction: MR imaging by using T1-shortening liposomes. Naresh NK, Xu Y, Klibanov AL, Vandsburger MH, Meyer CH, Leor J, Kramer CM, French BA, Epstein FH. Radiology. 2012 Aug;264(2):428-35. Epub 2012 Jun 21.

Myocardial tissue tracking with two-dimensional cine displacement-encoded MR imaging: development and initial evaluation. Kim D, Gilson WD, Kramer CM, Epstein FH. Radiology. 2004 Mar;230(3):862-71. Epub 2004 Jan 22.

Assessment of advanced coronary artery disease: advantages of quantitative cardiac magnetic resonance perfusion analysis. Patel AR, Antkowiak PF, Nandalur KR, West AM, Salerno M, Arora V, Christopher J, Epstein FH, Kramer CM. J Am Coll Cardiol. 2010 Aug 10;56(7):561-9.

Importance of k-space trajectory in echo-planar myocardial tagging at rest and during dobutamine stress. Kim D, Bove CM, Kramer CM, Epstein FH. Magn Reson Med. 2003 Oct;50(4):813-20.

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