Jason Druzgal, MD, PhD
Assistant Professor of Radiology
Functional neuroimaging of human cognition, with past emphasis on working memory and decision-making in normal human subjects. My current primary line of research uses functional magnetic resonance imaging (fMRI) to evaluate the theory of mind mechanism in both normal and autistic patients, with the hope of better understanding whether deficiencies in the theory of mind mechanism underlie the autism spectrum of disease. A secondary line of research focuses on evaluation of resting state abnormalities in autistic patients as compared with a control population, utilizing novel fMRI techniques for evaluating temporal synchrony. And a third line of research under development will investigate the diagnostic potential of resting state fMRI in autism, utilizing machine-learning algorithms. My programs of research utilize techniques that generalize to many types of cognitive pathology, but my current work with autism originates from ready access to patient populations within the Utah Autism Research Program.
Druzgal Lab: UVA Functional Neuroradiology Lab
Druzgal, T.J., Functional MRI of Theory of Mind: Parallel Game Paradigms. In preparation.
Anderson, J.S., et al., Decreased Interhemispheric Functional Connectivity in Autism. Cereb Cortex, 2011. 21(5): 1134-46.
Anderson, J.S., et al., Network Anticorrelations, Global Regression, and Phase-shifted Soft Tissue Correction (PSTCor). Hum Brain Mapp, 2011. 32(6): 919-34.
Anderson, J.S., et al., Decreased Left Posterior Insular Activity During Auditory Language in Autism. AJNR Am J Neuroradiol 2010 31(1): 131-139.
Landau, S.M., et al., A functional MRI study of the influence of practice on component processes of working memory. Neuroimage, 2004. 22(1): p. 211-21.
Postle, B.R., T.J. Druzgal, and M. D'Esposito, Seeking the neural substrates of visual working memory storage. Cortex, 2003. 39(4-5): p. 927-46.
Druzgal, T.J. and M. D'Esposito, Dissecting contributions of prefrontal cortex and fusiform face area to face working memory. J Cogn Neurosci, 2003. 15(6): p. 771-84.
Druzgal, T.J. and M. D'Esposito, Activity in fusiform face area modulated as a function of working memory load. Brain Res Cogn Brain Res, 2001. 10(3): p. 355-64.
Druzgal, T.J. and M. D'Esposito, A neural network reflecting decisions about human faces. Neuron, 2001. 32(5): p. 947-55.