Bijoy Kundu, Ph.D.
Assistant Professor of Radiology and Medical
University of Virginia
The general goal of my lab is to quantitatively evaluate myocardial glucose metabolism and blood flow, using Positron Emission Tomography (PET) imaging, in mouse heart in vivo. Current areas of focus include:
Zhong M, Alonso C, Tagetmeyer H, Kundu BK, Quantitative Positron Emission Tomography Imaging Detects Early Metabolic Remodeling in a Mouse Model of Pressure Overload Left Ventricular Hypertrophy in vivo, J Nucl Med (in press), 2012.
Zhong M, Kundu BK, Optimization of a Model Corrected Blood Input Function from Dynamic FDG-PET Images of Small Animal Heart in vivo. Presented at IEEE Medical Imaging Conference 2012, Manuscript submitted to IEEE Trans Nucl Sci, 2012.
Sen S, Kundu BK, et al., Early Metabolic Remodeling Activates mTOR and Impairs Contractile Function in the Stressed Rodent Heart, Manuscript under revision, JAHA, November 2012.
Li X, Zhang Y, Yang Z, Xu Y, Kundu BK et al, Synthesis of PECAM-1-specific 64Cu PET imaging agent: Evaluation of myocardial infarction caused by ischemia-reperfusion injury in mouse. Bioorg Med Chem Lett, 2012; 22(12):4144-7.
Zhong M, Locke LW, Kundu BK, Compartment Model Corrected Blood Input function Estimate Improves with Iterative Image Reconstruction and Cardiac Gating, Journal of Nucl. Med. abstracts, 2011; 52: 2104.
Alsonso C, Zhong M, Thornhill B, Figler R, Tagetmeyer H, Kundu BK, Metabolic Adaptation Precedes Maladaptive Response in Pressure Overload Induced Left Ventricular Hypertrophy in Mice: An In Vivo FDG-PET Study, Late Breaking Basic Science Abstracts, AHA Scientific Sessions. Circulation Research 2011; 109:e55-e63.
Locke LW, Williams MB, Fairchild KD, Zhong M, Kundu BK, Berr SS, FDG-PET Quantification of Lung Inflammation with Image-Derived Blood Input Function in Mice, International Journal of Molecular Imaging, Volume 2011, Article ID 356730, 2011. PMC3236466
Locke LW, Berr SS, Kundu BK, Image-Derived Input Function from Cardiac Gated Maximum a Posteriori Reconstructed PET Images in Mice, Molecular Imaging and Biology, Mol Imaging Biol. 2011 Apr;13(2):342-347. PMC3036775
Kundu BK, Figler R and Taegtmeyer H, Metabolic adaptation of the heart in a mouse model of Type 2 Diabetes Mellitus: A PET imaging study, AHA Scientific sessions. Circulation. 2010; 122:A12755.