Medication Development for Cocaine dependence is an 11 week clinical trial designed to test the efficacy of ondansetron in treating cocaine dependence. Patients who participate in this clinical trial will be asked to come to UVA C.A.R.E.'s outpatient clinic 3 times each week. The first weekly visit will last about 2 hours and the remaining 2 visits each week will last about 15 to 30 minutes each.

At these visits patients will receive the study medication ( or placebo), a physical examination, and cognitive behavioral therapy. Additionally, patient's will receive monetary compensation for their participation.  Compensation for the completed study is up to  $440.

The initial screening for this study is done over the telephone and takes 10-15 minutes. If there is nothing found from the telephone pre-screen that would make someone ineligible to participate, they would then come into the clinic for a more thorough in clinic screen which last 4 to 6 hours.  Principal Investigator: Nassima Ait-Daoud, M.D.

For more information or to complete a telephone pre-screen call:

434.243.0541 or 888.882.2345 (toll-free)