Christopher A. Moskaluk, M.D.,
Ph.D.
Professor of Pathology and Biochemistry
& Molecular Genetics
EDUCATION:
Medical School: Duke University
of Medicine 1982 - 1990 MD, PhD
Residency: Anatomic Pathology. Laboratory of
Pathology, National Cancer Institute of Health, Bethesda, MD. 1990 -
1993
Fellowship: Gastrointestinal Pathology. Department of
Pathology, John Hopkins University School of Medicine, Baltimore, MD.
1993 - 1995
CLINICAL:
Surgical
Pathology
RESEARCH:
Analysis of molecular
genetic events in human cancers, including molecular changes in
precursor lesions of malignant neoplasms.
REFERENCES:
- Baras, A., Yu, Y., Filtz, M., Kim, B., Moskaluk,
C.A. Combined genomic and gene expression microarray profiling
identifies ECOP as an up-regulated gene in squamous cell carcinomas
independent of DNA amplification. Oncogene advance online
publication 15 June 2009; doi: 10.1038/onc.2009.150.
- Hagan, K., Bienvenue, J., Moskaluk, C., Landers,
J. Microchip-based solid phase purification of RNA from biological
samples. Anal Chem 80:8453-60,
2008.
- Yu, Y., Baras, A.S., Frierson Jr., H.F., Moskaluk,
C.A. Concurrent loss of heterozygosity and copy number
abnormality analysis in adenoid cystic carcinoma by SNP genotyping
arrays. Lab Invest 87:430-435, 2007.
-
Stelow, E., Reid Adams, R., Moskaluk, C.
The prevalence of pancreatic intraepithelial neoplasia in pancreata
with uncommon types of primary neoplasms. Am J Surg
Pathol 30:36-41, 2006.
-
Raponi, M., Zhang, Y., Yu, J., Chen, G., Lee, G., Taylor, J. M. ,
Macdonald, J., Thomas, D., Moskaluk, C., Wang, Y.,
Beer, D. G. Gene expression signatures for predicting prognosis of
squamous cell and adenocarcinomas of the lung. Cancer
Res 66: 7466-72, 2006.
-
Hong, S.-M., Presley, A. E., Stelow, E.B., Frierson Jr., H.F.,
Moskaluk, C.A. Reconsideration of the histologic
definitions used in the pathological staging of extrahepatic
cholangiocarcinoma. Am J Surg Pathol
30:744-9, 2006.
-
Rutherford, S., Yu, Y., Rumpel, C.A., Frierson Jr., H.F.,
Moskaluk, C.A. Chromosome 6 deletion and tumor
suppressor genes in adenoid cystic carcinoma. Cancer
Lett 236:309-317, 2006.
-
Pramoonjago, P., Baras, A.S., Moskaluk, C.A.
Knockdown of Sox-4 expression by RNAi induces apoptosis in ACC3 cells.
Oncogene 25:5626-5639, 2006.
-
Moskaluk, C.A. Vanishing prostate cancer
syndrome: symptom of a larger clinical issue. Am J Surg
Pathol 29:561-3, 2005.
-
Moskaluk, C.A. Tissue processing re-visited: A
shifting paradigm in surgical pathology. Diagn Mol
Pathol 14:125-6, 2005.
-
Rutherford, S., Hampton, G.M., Frierson Jr., H.F.,
Moskaluk, C.A. Mapping of candidate tumor suppressor
genes on chromosome 12 in adenoid cystic carcinoma. Lab
Invest 85:1076-1085, 2005.
-
Welsh JB. Sapinoso LM. Kern SG. Brown DA. Liu T. Bauskin AR. Ward
RL. Hawkins NJ. Quinn DI. Russell PJ. Sutherland RL. Breit SN.
Moskaluk CA. Frierson HF Jr. Hampton
GM. Large-scale delineation of secreted protein biomarkers
overexpressed in cancer tissue and serum. Proc Natl Acad
Sci USA 100:3410-5, 2003.
-
Phillips, R.W., Frierson, Jr., H.F., and Moskaluk,
C.A. Cdx2 as a marker of epithelial intestinal differentiation
in the esophagus. Am J Surg Pathol
27:1442-47, 2003.
-
Moskaluk, C.A., Zhang, H., Powell, S.M., Cerilli,
L.A., Hampton G.M.. Frierson, Jr., H.F. Cdx2 protein expression
in normal and malignant human tissues: an immunohistochemical survey
using tissue microarrays. Mod
Pathol 16:913-9, 2003.
-
Moskaluk, C.A. Standardization of clinical
immunohistochemistry: Why, how and by whom? Am J Clin
Pathol 118:669-671, 2002.
-
Patel, S., Goldstein, M., Adams, R. and Moskaluk,
C.A. Genetic analysis of invasive carcinoma arising in
intraductal oncocytic papillary neoplasm of pancreas. Am J
Surg Pathol 26:1071-1077, 2002.
-
Moskaluk, C.A. and Stoler, M.H. Agarose mold
embedding of cultured cells for tissue microarrays. Diagn
Mol Pathol 11:234-238, 2002.
-
Frierson, Jr., H.F., El-Naggar, A.K., Welsh, J.B., Sapinoso, L.M.,
Su, A.I., Cheng, J, Saku, T, Moskaluk, C.A., and
Hampton, G.M. Large scale molecular analysis identifies genes with
altered expression in salivary adenoid cystic carcinoma. Am
J Pathol 161:1315-23, 2002.
BOOK CHAPTERS:
- Moskaluk, C.A. (2004) Molecular pathology
laboratory of the future. In Dissecting the Molecular Anatomy of
Tissue (Emmert-Buck, Gillespie, Chuaqui, eds.,
Springer-Verlag, Heidelberg, Germany).
- Moskaluk, C. (2003) Esophagus. In Modern
Surgical Pathology 1st Ed. (Weidner,
N., et al eds.; W.B. Saunders Co., Philadelphia) pp.
631-667.
- Moskaluk, C.A. (2000) Microdissection of
histologic sections: Manual and Laser Capture Microdissection
Techniques. In Colorectal Cancer Methods and Protocols (Humana
Press, Totowa, New Jersey) pp 1-13.
A more complete list of Dr. Moskaluk's publications can be
found from
PubMed
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