Doris M. Haverstick, Ph.D.

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Doris M. Haverstick, Ph.D.


HaverstickDede 

Doris M. (Dede) Haverstick, Ph.D.

Associate Professor of Pathology

Director of Toxicology, Point of Care Testing

and Specimen Collection and  Management

Associate Director of Clinical Chemistry

Quality and Advisor for the Department of Pathology

 

EDUCATION:

 

Graduate Education: St. Louis University  School of Medicine, 1982, Ph.D. in Pharmacology

1983 - 1985: Fellow in Lab Medicine, Washington University

1985 - 1987: Post Doctoral Fellow, Dept. of Biochemistry, University of Illinois

1987 - 1989: Research Associate, Mount Sinai Hospital of Detroit (Center for Cell Biology)

CLINICAL:

  • Toxicology: the identification of the agent inducing acute illness and the consequences of environmental pathogens.

  • Molecular Diagnostics: use of new techniques in molecular diagnostics, with emphasis on real-time PCR for rapid, definitive diagnosis.

  • Management of both financial and personnel resources in the face of changes in health care delivery, including the growth of point of care testing. Specific emphasis on decreasing personnel resources with increasing automation and complexity of tests performed and the impact on quality assurance activities and the need to meet regulatory requirements of multiple agencies (TJC, CAP, CMS, etc.).

 

RESEARCH:

The cell biology of signal transduction pathways involving changes in intracellular free Ca leading to proliferation (growth). Our model systems include the study of lymphocytes, breast and prostate cancer. Our goal is to understand calcium signaling pathways and use this information to develop new antiproliferative compounds for use in the control of human cancers in a cytostatic manner.

REFERENCES:  

Manuscripts - 

  • Heady TN, Haverstick D: Heroin: a worsening problem and a challenge for testing. MLO Med Lab Obs 2014, 46:22-23. http://www.ncbi.nlm.nih.gov/pubmed/25158398.
  • Liu J, Kabir F, Manneh J, Lertsethtakarn P, Begum S, Gratz J, Becker SM, Operario DJ, Taniuchi M, Janaki L, Platts-Mills J, Haverstick DM, Kabir M, Sobuz SU, Nakjarung K, Sakpaisal P, Silapong S, Bodhidatta L, Qureshi S, Kalam A, Saidi Q, Swai N, Mujaga B, Maro A, Kwambana B, Dione M, Antonio M, Kibiki G, Mason CJ, Haque R, Iqbal N, Zaidi AK, Houpt ER: Development and assessment of molecular diagnostic tests for 15 enteropathogens causing childhood diarrhoea: a multicentre study. Lancet Infect Dis 2014, 14:716-724. http://www.ncbi.nlm.nih.gov/pubmed/25022434. DOI: 10.1016/S1473-3099(14)70808-4.
  • Vakkalanka P, Rushton WF, Hardison LS, Bishop MC, Haverstick DM, Holstege CP: Evaluation of the initiation of urine drug screens intended for use in transfer patients. Am J Emerg Med 2014, 32:1037-1040. http://www.ncbi.nlm.nih.gov/pubmed/25070191. DOI: 10.1016/j.ajem.2014.06.011.
  • Wendroth SM, Heady TN, Haverstick DM, Bachmann LM, Scott MG, Boyd JC, Bruns DE: Falsely increased chloride and missed anion gap elevation during treatment with sodium thiosulfate. Clin Chim Acta 2014, 431:77-79. http://www.ncbi.nlm.nih.gov/pubmed/24508994. DOI: 10.1016/j.cca.2014.01.020.
  • Li J, Liu Q, Xiao L, Haverstick DM, Dewald A, Columbus L, Kelly K, Landers JP: Label-free method for cell counting in crude biological samples via paramagnetic bead aggregation. Anal Chem 2013, 85:11233-11239. http://www.ncbi.nlm.nih.gov/pubmed/24187938. DOI: 10.1021/ac401402h.
  • Liu J, Gratz J, Amour C, Kibiki G, Becker S, Janaki L, Verweij JJ, Taniuchi M, Sobuz SU, Haque R, Haverstick DM, Houpt ER: A laboratory-developed TaqMan Array Card for simultaneous detection of 19 enteropathogens. J Clin Microbiol 2013, 51:472-480. http://www.ncbi.nlm.nih.gov/pubmed/23175269. DOI: 10.1128/JCM.02658-12. 
  •  Mitsios JV, Ashby LA, Haverstick DM, Bruns DE, Scott MG: Analytic evaluation of a new glucose meter system in 15 different critical care settings. J Diabetes Sci Technol 2013, 7:1282-1287. http://www.ncbi.nlm.nih.gov/pubmed/24124955.
  •  Vakkalanka P, Rushton WF, Hardison LS, Bishop MC, Haverstick DM, Holstege CP: Evaluation of the initiation of urine drug screens intended for use in transfer patients. CLINICAL TOXICOLOGY 2013, 51:581-582. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000322204400025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=cfc784e19a5045db07524a7304ce6a05
  •  Lounsbury JA, Karlsson A, Miranian DC, Cronk SM, Nelson DA, Li J, Haverstick DM, Kinnon P, Saul DJ, Landers JP: From sample to PCR product in under 45 minutes: a polymeric integrated microdevice for clinical and forensic DNA analysis. Lab Chip 2013, 13:1384-1393. http://www.ncbi.nlm.nih.gov/pubmed/23389252. DOI: 10.1039/c3lc41326h.
  • Kelly BN, Haverstick DM, Vance ML, Thorner MO, Bruns DE: Quantification of growth hormone mRNA in blood. Clin Chim Acta 2012, 414:206-210. http://www.ncbi.nlm.nih.gov/pubmed/22985689. DOI: 10.1016/j.cca.2012.09.011.

 

 

 

 

 

Book Chapters -

  • D.M Haverstick and A. R. Groszbach. Specimen Collection and Processing.  In Fundamentals of Molecular Diagnostics, DE Bruns, ER Ashwood, and CA Burtis, eds.  Elsevier, 2007.
  • D.S. Young, E.W. Bermes, and D.M. Haverstick.  Specimen Collection and Other Preanalytical Variables.  In Fundamentals of Clinical Chemistry, CA Burtis, ER Ashwood, and DE Bruns, eds.  Elsevier, 2008.

A more complete list of Dr. Haverstick's publications can be obtained from PubMed.