David E. Bruns, M.D.
Professor of Pathology
Director of Clinical Chemistry
Associate Director of Molecular
Co-Director, Fellowship in Clinical
Chemistry and Laboratory Medicine
Medical School: St. Louis University, MD, 1973
Residency and Fellowship: Departments of Pathology and Internal
Medicine, Washington University, 1973-1977
Clinical chemistry and molecular
Bruns DE, Ashwood ER, Burtis CA,
eds. Fundamentals of Molecular Diagnostics. St. Louis:
Burtis CA, Ashwood ER, Bruns DE,
eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics,
5th ed., St. Louis: Saunders/Elsevier, 2012.
Burtis CA, Bruns DE, eds. Tietz
Fundamentals of Clinical Chemistry and Molecular Diagnostics. 7th ed.
St. Louis: Saunders/Elsevier, 2015
, Burtis CA, Gronowski
AM, McQueen MJ, Newman A, Jonsson JJ, IFCC Task Force oE: Variability
of ethics education in laboratory medicine training programs: results
of an international survey. Clin Chim Acta 2015, 442:115-118. http://www.ncbi.nlm.nih.gov/pubmed/25437910
Krinsley JS, Bruns DE
JC: The impact of measurement frequency on the domains of glycemic
control in the critically ill--a Monte Carlo simulation. J Diabetes Sci
Technol 2015, 9:237-245. http://www.ncbi.nlm.nih.gov/pubmed/25568143
Kelly BN, Haverstick DM, Lee JK, Thorner MO,
Vance ML, Xin W, Bruns DE
: Circulating microRNA as a
biomarker of human growth hormone administration to patients. Drug Test
Anal 2014, 6:234-238. http://www.ncbi.nlm.nih.gov/pubmed/23495241
Wendroth SM, Heady TN, Haverstick DM,
Bachmann LM, Scott MG, Boyd JC, Bruns DE
increased chloride and missed anion gap elevation during treatment with
sodium thiosulfate. Clin Chim Acta 2014, 431:77-79. http://www.ncbi.nlm.nih.gov/pubmed/24508994
Boyd JC, Bruns DE
: Effects of
measurement frequency on analytical quality required for glucose
measurements in intensive care units: assessments by simulation models.
Clin Chem 2014, 60:644-650. http://www.ncbi.nlm.nih.gov/pubmed/24430017
Algeciras-Schimnich A, Bruns
, Boyd JC, Bryant SC, La Fortune KA, Grebe SK: Failure of
current laboratory protocols to detect lot-to-lot reagent differences:
findings and possible solutions. Clin Chem 2013, 59:1187-1194. http://www.ncbi.nlm.nih.gov/pubmed/23592508
Bachmann LM, Nilsson G, Bruns
, McQueen MJ, Lieske JC, Zakowski JJ, Miller WG: State of
the art for measurement of urine albumin: comparison of routine
measurement procedures to isotope dilution tandem mass spectrometry.
Clin Chem 2014, 60:471-480. http://www.ncbi.nlm.nih.gov/pubmed/24281781
McCudden CR, Senior BA, Hainsworth S,
Oliveira W, Silverman LM, Bruns DE
, Hammett-Stabler C:
Evaluation of high resolution gel Î²(2)-transferrin for detection of
cerebrospinal fluid leak. Clin Chem Lab Med 2013, 51:311-315. http://www.ncbi.nlm.nih.gov/pubmed/23023885
Mitsios JV, Ashby LA, Haverstick DM,
, Scott MG: Analytic evaluation of a new
glucose meter system in 15 different critical care settings. J Diabetes
Sci Technol 2013, 7:1282-1287. http://www.ncbi.nlm.nih.gov/pubmed/24124955
SELECTED INVITED LECTURES
Bruns DE. Optimal Glucose Monitoring. 31st International Symposium
on Intensive Care and Emergency Medicine. Brussels, March 22-25,
2011.Bruns DE. Are glucose meters up to the task of TGC? 2011 Arnold O.
Beckman Conference. San Diego, April 12-13, 2011.
Bruns DE, Boyd JC. POCT Glucose measurement and its limitations.
21st International Congress of Clinical Chemistry and Laboratory
Medicine. Berlin, May 15-20, 2011.
Bruns DE. Accuracy requirements for glucose assays used to
support intensive insulin therapy. Diabetes Diagnostics. Zwolle, The
Netherlands, September 20, 2011.
Bruns DE. Desirable performance for point-of-care glucose
measurements in hospital settings. EUROMEDLAB Milano. 20th IFCC-EFCC
European Congress of Laboratory Medicine. 45th Congress of the Italian
Society of Clinical Biochemistry and Clinical Molecular Biology. Milan,
Italy. May 19-23, 2013.
Bruns DE. Desirable analytical performance of continuous glucose
monitors. IFCC WORLDLAB Congress, International Federation of Clinical
Chemistry. Istanbul, June 22-26, 2014.
A current list of Dr. Bruns' peer-reviewed
publications is available from