David E. Bruns, M.D.
Professor of Pathology
Director of Clinical Chemistry
Associate Director of Molecular
Co-Director, Fellowship in Clinical
Chemistry and Laboratory Medicine
Medical School: St. Louis University, MD, 1973
Residency and Fellowship: Departments of Pathology and Internal
Medicine, Washington University, 1973-1977
Clinical chemistry and molecular
Bruns DE, Ashwood ER, Burtis CA,
eds. Fundamentals of Molecular Diagnostics. St. Louis:
Burtis CA, Ashwood ER, Bruns DE,
eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics,
5th ed., St. Louis: Saunders/Elsevier, 2012.
Burtis CA, Bruns DE, eds. Tietz
Fundamentals of Clinical Chemistry and Molecular Diagnostics. 7th ed.
St. Louis: Saunders/Elsevier, 2015
- Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA,
Glasziou PP, Irwig LM, Lijmer JG, Moher
D, Rennie D, DeVet HC. Towards complete and accurate reporting of
studies of diagnostic accuracy: The STARD
Initiative. Ann Intern Med 2003; 138:40-44 (and 14 other
- Sacks, DB, Arnold A, Bakris GL, Bruns DE, Horvath
AR, Kirkman SK , Lernmark A, Metzger BE , Nathan DM. Executive
summary: guidelines and recommendations for laboratory analysis in the
diagnosis and management of diabetes mellitus. Clin Chem 2011;57:793-8
and Diabetes Care 2011;34:1419-23.
- Sacks DB, Bruns DE, Horton J, Lindberg S, Mahoney
JJ, Manzella S, Reilly ET, Scott MG. Point-of-care blood glucose
testing in acute and chronic care facilities: approved guideline.
Clinical Laboratory Standards Institute 2013;33:1-48.
- Algeciras-Schimnich A, Bruns DE, Boyd JC, Bryant
S, La Fortune KA, Grebe SKG. Failure of current laboratory protocols to
detect lot-to-lot reagent differences: Findings and possible solutions.
Clin Chem 2013;59:1187-94. (Related Editorial: Bennett ST. Clin Chem
- Kelly BN, Haverstick DM, Lee JK, Thorner MO, Vance ML, Xin W,
Bruns DE. Circulating microRNA as a biomarker of human
growth hormone administration to patients. Drug Test Anal
- Mitsios JV, Ashby LA, Haverstick DM, Bruns DE,
Scott MG. Analytic evaluation of a new glucose meter system in 15
different critical care settings. Diabetes Sci Technol
- Bachmann LM, Nilsson G, Bruns DE, McQueen MJ,
Lieske JC, Zakowski JJ, Miller WG. State of the art for measurement of
urine albumin: comparison of routine measurement procedures to isotope
dilution tandem mass spectrometry. Clin Chem 2014;60:471-80. (Related
Editorial: Scott MG, Coyne DW. Clin Chem 2014;60:435-7.)
- Boyd JC, Bruns DE. Effects of measurement
frequency on analytical quality required for glucose measurements in
ICUs: assessments by simulation models. Clin Chem 2014;60:644-50.
(Related Editorial: Van den Berghe G. Clin Chem 2014;60:577-9).
SELECTED INVITED LECTURES
Bruns DE. Optimal Glucose Monitoring. 31st International Symposium
on Intensive Care and Emergency Medicine. Brussels, March 22-25,
2011.Bruns DE. Are glucose meters up to the task of TGC? 2011 Arnold O.
Beckman Conference. San Diego, April 12-13, 2011.
Bruns DE, Boyd JC. POCT Glucose measurement and its limitations.
21st International Congress of Clinical Chemistry and Laboratory
Medicine. Berlin, May 15-20, 2011.
Bruns DE. Accuracy requirements for glucose assays used to
support intensive insulin therapy. Diabetes Diagnostics. Zwolle, The
Netherlands, September 20, 2011.
Bruns DE. Desirable performance for point-of-care glucose
measurements in hospital settings. EUROMEDLAB Milano. 20th IFCC-EFCC
European Congress of Laboratory Medicine. 45th Congress of the Italian
Society of Clinical Biochemistry and Clinical Molecular Biology. Milan,
Italy. May 19-23, 2013.
Bruns DE. Desirable analytical performance of continuous glucose
monitors. IFCC WORLDLAB Congress, International Federation of Clinical
Chemistry. Istanbul, June 22-26, 2014.
A current list of Dr. Bruns' peer-reviewed
publications is available from