James C. Boyd, M.D.

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James C. Boyd, M.D.

James C. Boyd, M.D. Faculty Profile



James C. Boyd, M.D.

Associate Professor of Pathology

Director of Clinical Pathology

Director of Core Laboratory Automation

Director of Systems Engineering

Associate Director of Clinical Chemistry and Toxicology

Director of Student Health Laboratory



Medical School: Washington University School of Medicine, St. Louis, MO. M.D. - 1973

Residency: Barnes Hospital, Division of Laboratory Medicine, Departments of Pathology and Internal Medicine Washington University


Medical informatics and clinical chemistry with emphasis on lipid analysis, quality control and automation.



Use of mathematical and statistical approaches for aiding the evaluation and clinical interpretation of laboratory tests; development and evaluation of automation in the clinical laboratory.



Deputy Editor, Clinical Chemistry, 2007 - present



  1. Boyd JC, Bruns DE.  Monte Carlo simulation in establishing goals for analytical performance of clinical laboratory tests: meeting clinical needs. In Johnson ML, Brand L, eds: Meth Enzymol 2009;467:411-33.
  2. Boyd JC.  Defining laboratory reference values and decision limits:  populations, intervals, and interpretations.  Asian J Androl 2010 Jan;12(1):83-90.
  3. Bruns DE, Boyd JC.  Few point-of-care hemoglobin A1c assay methods meet clinical needs. Clin  Chem. 2010 Jan;56(1):4-6.
  4. Karon BS, Boyd JC, Klee GG.  Glucose meter performance criteria for tight glycemic control estimated by simulation modeling.  Clin Chem. 2010 Jul;56(7):1091-7.
  5. Bruns DE, Boyd JC.  Assessing the impact of biomarkers on patient outcome: an obligatory step.  Scand J Clin Lab Invest Suppl. 2010 Jul;242:85-9.
  6. Ichihara K, Boyd JC; IFCC Committee on Reference Intervals and Decision Limits (C-RIDL).  An appraisal of statistical procedures used in derivation of reference intervals. Clin Chem Lab Med. 2010 Nov;48(11):1537-51.
  7. Ceriotti F, Henny J, Queraltó J, Ziyu S, Özarda Y, Chen B, Boyd JC, Panteghini M; IFCC Committee on Reference Intervals and Decision Limits (C-RIDL); Committee on Reference Systems for Enzymes (C-RSE). Common reference intervals for aspartate aminotransferase (AST), alanine aminotransferase (ALT) and -glutamyl transferase (GGT) in serum: results from an IFCC multicenter study. Clin Chem Lab Med. 2010 Nov;48(11):1593-601.
  8. Rifai N, Annesley T, Boyd J. International Year of Chemistry 2011: Clinical Chemistry celebrates.  Clin Chem. 2010 Dec;56(12):1783-5.
  9. Bellizzi AM, Legallo RD, Boyd JC, Iezzoni JC.  Hepatocyte cytokeratin 7 expression in chronic allograft rejection. Am J Clin Pathol. 2011 Feb;135(2):238-44.
10. Rifai N, Boyd JC, Annesley TM. Clinical Chemistry Trainee Council: A new journal initiative. Clin Chem. 2011;57:935.
11. Boyd JC. Biologic rhythms and test interpretation. Scand J Clin Lab Invest 2011; 71: 529-531.
12. Boyd JC, Rifai N, Annesley T. Statistical methods for test and biomarker evaluation studies: a clinical chemistry series. Clin Chem. 2012 Sep;58(9):1273-4.

A current list of Dr. Boyd's journal publications can be obtained from PubMed.