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Mark Abel, MD Lillian T.
Pratt Distinguished Professor of Orthopaedic Surgery; Professor of
Pediatrics; Chair, Department of Orthopaedic Surgery; Medical Director,
University of Virginia Motion Analysis and Motor Performance
Laboratory; Division Head, Division of Pediatric Orthopaedics. Current
research activities include outcome and surgical decisions in childhood
onset spinal deformity. He also has done extensive research on cerebral
palsy; natural development of gait and motor skills in diplegic
cerebral palsy; effective muscle co-activation or forced generation in
cerebral palsy; use of bracing in diplegic cerebral palsy and relation
of energy expenditure index and motor function. Other clinical research
interests include treatment of management of hip dysplasia .
Gary Balian, PhD Professor of
Orthopaedics and Professor of Biochemistry and Molecular Genetics,
Director of Orthopaedic Research Laboratories, and Director of T32
Musculoskeletal Research Training Program. Dr. Balian is an
internationally recognized cell biologist. He is responsible for
coordinating the overall schedule for the basic science lecture series
and oversees the residents involved in laboratory research. He is also
responsible for instruction in biochemical aspects of orthopaedics. His
research interests involve prostate cancer cell-bone marrow adhesion
mediators. The contribution of this research to our understanding of
cancer cell homing to bone may be forthcoming from the identification
of molecular targets in bone. Bone repair is clearly a very important
area of consideration in the field of musculoskeletal tissue
regeneration. Inclusion of bone targeting factors in synthetic or
natural polymers potentiate repair through mechanisms that are well
characterized biologically at the cellular and molecular levels. Two
unique bone targeting peptides potentiate the differentiation of
mesenchymal cells in vitro, moreover, the peptides promote bone repair
in critical sized unicortical defects. The potential anabolic effects
of these novel peptides on bone density and gene expression is under
investigation.
Bradford C Bennett, PhD
Assistant Professor of Orthopaedic Surgery and Mechanical and Aerospace
Engineering, Research Director of the Motion Analysis and Motor
Performance Laboratory. Prof. Bennett’s major research interests are in
the organization, control, and biomechanics of human movement,
especially walking. His research involves using biomechanics as a
window into the organization of human movement and to develop advanced
walking aids for children with cerebral palsy and others with walking
disabilities. Current research includes the investigation of the use of
a powered lower body exoskeleton by individuals that can not walk and
the development of a powered walker by children with cerebral palsy and
the elderly. Dr. Bennett also leads student teams that design and
develop devices and systems to assist children with disabilities for
the patients and clinicians at the Kluge Children’s Rehabilitation
Center.
Thomas E. Brown, MD
Associate Professor of Orthopaedic Surgery. Involved in clinical
trials for novel implants in adult reconstructive surgery and spine and
joint infection antagonists.
Eric W. Carson, MD
Associate Professor, University of Virginia; Medical Clinical Director,
McCue Sports Medicine Center. Osteochondral injuries, ligament grafts,
shoulder instability (articular cartilage matrix degradation,
biomechanics, anatomy, physiology and cartilage research).
A. Bobby Chhabra, MD Associate
Professor of Orthopaedic Surgery; Division Head, Hand Surgery and Vice
Chair. Area of expertise: hand, wrist, elbow, and peripheral nerve
surgery. Research interests include upper extremity fracture
fixation, tendon repair, microvascular surgery, growth factor and
tissue engineering techniques for flexor tendon repair.
Quanjun Cui, MD Assistant
Professor, Department of Orthopaedic Surgery; Chief Orthopaedic Trauma
Service; Medical Director, 6-East, Orthopaedic Surgery and Trauma.
Research interests include (1) cellular and gene therapy for
musculoskeletal diseases including osteonecrosis and fractures, (2)
development of novel composite bone graft substitutes for the treatment
of fractures and bone defects, and (3) pathogenesis and treatment of
osteonecrosis of the femoral head.
Rashard Dacus, MD Assistant
Professor, Department of Orthopaedic Surgery. His research looks at
tendon adhesion following repair as the process relates the
mobilization protocols and the effect of growth factors on repair
patterns.
Nicole Deal, MD Assistant
Professor, Department of Orthopaedic Surgery. Her research has
focused on nerve repair using different neurorrhaphy techniques,
including external fixator-assisted primary neurorrhaphy. She also has
examined the effect of ice on reducing microvascular permeability
following contusion.
David Diduch, MD
Professor, University of Virginia; Head Orthopaedic Team Physician;
Director, Sports Medicine Fellowship Program. Shoulder and knee
surgery, in growth factor and cellular cartilage repair research with
cells and growth factors as well as clinical sports medicine
research.
Joseph Hart, PhD Assistant Professor, Department of
Orthopaedic Surgery. The nearly ubiquitous incidence of
early-onset osteoarthritis in the post-traumatic knee makes research in
this patient group exciting and challenging. Among the many
contributing factors are exercise-related neuromuscular changes in the
presence of muscle dysfunction. I have investigated the effects
of gender, core instability and previous joint injury on quadriceps
muscle function, balance and neuromuscular performance during
activities. Therefore, my research will continue to focus on
basic science (including animal models), translational and clinical
trials research to provide the best evidence based treatments for
active persons who are at risk for knee injury, re-injury and
degeneration.
Xudong (Joshua) Li, MD, PhD
Assistant Professor, Department of Orthopaedic Surgery. His
research interests is in the restoration of a functional disc by an ex
vivo approach using transplanted ADAS cells that are transduced with
Ad-GDF-5 into the annulus of an injured disc. This research on GDF-5
engineered ADAS cells and the in vivo characterization of the disc
could lead to a novel approach for the treatment of late stage disc
injury or degeneration, and, if successful data from this project will
support the effort to achieve disc repair in humans.
David M. Kahler, MD
Associate Professor of Orthopaedics with fellowship training in Sports
Medicine and Hand Surgery. Special interest in trauma surgery and
computer assisted surgery. His research centers around development of
new techniques and workflows in image guided surgery and validation of
existing techniques. Current work emphasizes expansion of
existing techniques for pelvic fractures toward use in routine
long-bone fracture care.
Mark Miller, MD
Assistant Professor, responsible for OITE review and Basic Science
research in sports medicine and hamstring regeneration research.
(Shoulder, Knee, Anatomy, Physiology)
Mark J. Romness, MD
Assistant Professor of Orthopaedic Surgery, Division of Pediatric
Orthopaedic Surgery; Secondary App't in Pediatrics. He has focused on
the treatment of children with musculoskeletal problems and the
effectiveness of those treatments. Children with cerebral palsy
and related disorders represent a sub-specialized area of his career.
Motion analysis, cerebral palsy and muscle lengthening.
Francis Shen, MD
Associate Professor, Involved with research involving improved fusion
capacity following spinal decompression and instrumentation, spine
surgery, spine fusion and mesenchymal cell based bone grafts for spine
fusion. The purpose of his research is to develop a bone graft
substitute that places osteogenic precursors, in the form of
multipotential adipose-derived stromal cells, within bioabsorbable
osteoconductive microspheres combined with an osteoinductive growth
factor.
Adam Shimer, MD
Assistant Professor, Orthopaedic Surgery. Treatment using gene therapy
for intervertebral disc degeneration.
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