PO Box 801412, Fontaine Research Park 450 Ray C. Hunt Drive
Phone: (434) 243-2603
Fax: 9434) 243-9143
E-mail: acd6v@virginia.edu

Research Interest: Reproductive Endocrinology

Publications

1.  Burger LL, Haisenleder DJ, Wotton GM, Aylor KW, Dalkin AC, Marshall JC.  The regulation of FSHbeta transcription by gonadal steroids: testosterone and estradiol modulation of the activin intracellular signaling pathway. Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E277-85. Epub 2007 Apr 3.

2.  Haisenleder DJ, Aylor KW, Burger LL, Dalkin AC, Marshall JC.  Stimulation of FSHbeta transcription by blockade of endogenous pituitary follistatin production: Efficacy of adenoviral-delivered antisense RNA in the rat.  Endocrine. 2006 Jun;29(3):399-404.

3.  Burger LL, Haisenleder DJ, Dalkin AC, Marshall JC.  Regulation of gonadotropin subunit gene transcription. J Mol Endocrinol. 2004 Dec;33(3):559-84. Review.

4.  Haisenleder DJ, Burger LL, Aylor KW, Dalkin AC, Walsh HE, Shupnik MA, Marshall JC.  Testosterone stimulates follicle-stimulating hormone beta transcription via activation of extracellular signal-regulated kinase: evidence in rat pituitary cells.  Biol Reprod. 2005 Mar;72(3):523-9. Epub 2004 Oct 27.

5.  Prendergast KA, Burger LL, Aylor KW, Haisenleder DJ, Dalkin AC, Marshall JC.  Pituitary follistatin gene expression in female rats: evidence that inhibin regulates transcription.  Biol Reprod. 2004 Feb;70(2):364-70. Epub 2003 Oct 15.
 
6.  Burger LL, Haisenleder DJ, Aylor KW, Dalkin AC, Prendergast KA, Marshall JC.  Regulation of luteinizing hormone-beta and follicle-stimulating hormone (FSH)-beta gene transcription by androgens: testosterone directly stimulates FSH-beta transcription independent from its role on follistatin gene expression.  Endocrinology. 2004 Jan;145(1):71-8. Epub 2003 Sep 25.
 
7.  Haisenleder DJ, Burger LL, Aylor KW, Dalkin AC, Marshall JC.  Gonadotropin-releasing hormone stimulation of gonadotropin subunit transcription: evidence for the involvement of calcium/calmodulin-dependent kinase II (Ca/CAMK II) activation in rat pituitaries.  Endocrinology. 2003 Jul;144(7):2768-74.
 
8.  Burger LL, Dalkin AC, Aylor KW, Haisenleder DJ, Marshall JC.  GnRH pulse frequency modulation of gonadotropin subunit gene transcription in normal gonadotropes-assessment by primary transcript assay provides evidence for roles of GnRH and follistatin. Endocrinology. 2002 Sep;143(9):3243-9.
 
9.  Haisenleder DJ, Workman LJ, Burger LL, Aylor KW, Dalkin AC, Marshall JC.  Gonadotropin subunit transcriptional responses to calcium signals in the rat: evidence for regulation by pulse frequency.  Biol Reprod. 2001 Dec;65(6):1789-93.
 
10.  Burger LL, Dalkin AC, Aylor KW, Workman LJ, Haisenleder DJ, Marshall JC.  Regulation of gonadotropin subunit transcription after ovariectomy in the rat: measurement of subunit primary transcripts reveals differential roles of GnRH and inhibin.  Endocrinology. 2001 Aug;142(8):3435-42.
 
11.  Dalkin AC, Burger LL, Aylor KW, Haisenleder DJ, Workman LJ, Cho S, Marshall JC.  Regulation of gonadotropin subunit gene transcription by gonadotropin-releasing hormone: measurement of primary transcript ribonucleic acids by quantitative reverse transcription-polymerase chain reaction assays.  Endocrinology. 2001 Jan;142(1):139-46.
 
12.  Dalkin AC, Haisenleder DJ, Gilrain JT, Aylor K, Yasin M, Marshall JC.  Gonadotropin-releasing hormone regulation of gonadotropin subunit gene expression in female rats: actions on follicle-stimulating hormone beta messenger ribonucleic acid (mRNA) involve differential expression of pituitary activin (beta-B) and follistatin mRNAs.  Endocrinology. 1999 Feb;140(2):903-8.

13.  Dalkin AC, Haisenleder DJ, Gilrain JT, Aylor K, Yasin M, Marshall JC.  Regulation of pituitary follistatin and inhibin/activin subunit messenger ribonucleic acids (mRNAs) in male and female rats: evidence for inhibin regulation of follistatin mRNA in females.  Endocrinology. 1998 Jun;139(6):2818-23.
 
14.  Aloi JA, Marshall JC, Yasin M, Gilrain JT, Haisenleder DJ, Dalkin AC.  Ovarian activin receptor subtype and follistatin gene expression in rats: reciprocal regulation by gonadotropins.  Biol Reprod. 1997 Jun;56(6):1565-9.
 
15.  Haisenleder DJ, Yasin M, Dalkin AC, Gilrain J, Marshall JC.  GnRH regulates steroidogenic factor-1 (SF-1) gene expression in the rat pituitary.  Endocrinology. 1996 Dec;137(12):5719-22.

16.  Dalkin AC, Gilrain JT, Bradshaw D, Myers CE.  Activin inhibition of prostate cancer cell growth: selective actions on androgen-responsive LNCaP cells.  Endocrinology. 1996 Dec;137(12):5230-5.
 
17.  Yasin M, Dalkin AC, Haisenleder DJ, Marshall JC.  Testosterone is required for gonadotropin-releasing hormone stimulation of luteinizing hormone-beta messenger ribonucleic acid expression in female rats.  Endocrinology. 1996 Apr;137(4):1265-71.

18.  Dalkin AC, Haisenleder DJ, Yasin M, Gilrain JT, Marshall JC.  Pituitary activin receptor subtypes and follistatin gene expression in female rats: differential regulation by activin and follistatin.  Endocrinology. 1996 Feb;137(2):548-54.

19.  Matherne GP, Byford AM, Gilrain JT, Dalkin AC.  Changes in myocardial A1 adenosine receptor and message levels during fetal development and postnatal maturation. Biol Neonate. 1996;70(4):199-205.
 
20.  Kerrigan JR, Yasin M, Haisenleder DJ, Dalkin AC, Marshall JC.  Regulation of gonadotropin subunit messenger ribonucleic acid expression in gonadotropin-releasing hormone (GnRH)-deficient female rats: effects of GnRH, galanin, GnRH-associated peptide, neuropeptide-Y, and thyrotropin-releasing hormone.
Biol Reprod. 1995 Jul;53(1):1-7.

Updates on Recent Publications