Y. Michael Shim, MD

Y. Michael Shim, MD

Shim, Michael








Y. Michael Shim, MD


Associate Professor of Medicine
Medical Director, Pulmonary Function Laboratories
Director, COPD Clinic

Fellowship: Yale University
Office Address: P.O. Box 800546

Division of Pulmonary and Critical Care Medicine
University of Virginia Health System
Charlottesville, VA 22908

Phone: 434-924-5210
FAX: 434-924-9682
Board Certifications: Internal Medicine
Pulmonary Disease
Critical Care Medicine
Clinics: UVA Pulmonary Clinic:  434-924-5219
Clinical Practice: Chronic obstructive pulmonary disease, allergy, lung cancer.
Research Interests: COPD, chronic bronchitis, emphysema, asthma, lung cancer, pulmonary inflammation and remodeling.

Publications (selected):

Shim YM, Burnette A, Lucas S, et al. Physical deconditioning as a cause of breathlessness among obese adolescents with a diagnosis of asthma. PLoS One 8:e61022, 2013.

Juncadella IJ, Kadl A, Sharma AK, et al. Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation. Nature 493:547-551, 2012.

Mata J, Altes T, Truwit J, Sylvester P, de Ainge E, Shim YM, Vinayak A, Brookeman J, Mugler J: Characterization and detection of physiologic lung changes before and after placement of bronchial valves using hyperpolarized helium-3 MR imaging: preliminary study. Acad Radiol 18:1195-1199, 2011.

Paige M, Kim SH, Burdick MA, Xu Z, Lee J, Shim YM: Pilot analysis of the plasma metabolite profiles associated with emphysematous chronic obstructive pulmonary disease phenotype. BBRC. 2011 Oct 7;413(4):588-93.

De Olivera EO, Wang K, Kong HS, Kim SH, Miessau M, Snelgrove RJ, Shim YM*, Mikell P*: Effect of the leukotriene A4 hydrolase aminopeptidase augmentor 4-methoxydiphenylmethane in a pre-clinical model of pulmonary emphysema. Bioorg & Medicinal Chem Let. 2011 Nov 15;21(22):6746-50.

Enfield K, Shim YM. Six minute walk distance in severe end-stage COPD patients: Association with survival after inpatient pulmonary rehabilitation. Journal of Cardiopulmonary Rehabilitation and Prevention 2010;30:195-202.

Snelgrove RJ, Jackson PL, Hardison MT, Noerager BD, Kinlock A, Gaggar A, Shastry S, Rowe S, Shim YM, Hussel T, Blalock JE. A critical role for LATA4H in limiting chronic pulmonary neutrophilic inflammation. Science 2010;330:90-94.

Shim YM, Strieter RM. Role of LTB4 in the pathogenesis of elastase-induced murine pulmonary emphysema. American Journal of Physiology:Lung Cell and Molecular Physiology 2010;299:L749-L759.

Sharma G, Shim YM. The aging immune system and its relationship to the development of COPD. Proceedings of the American Thoracic Society 2009;6:573-580.

Chupp GL, Lee CG, Jarjour N, Shim YM, Holm CT, He S, Dziura JD, Reed J, Coyle AJ, Kiener P, Cullen M, Grandsaigne M, Dombret MC, Aubier M, Pretolani M, and Elias JA. A chitinase-like protein in the lung and circulation of patients with severe asthma. New England Journal of Medicine 2007;357:2016-2027.