Robert M. Strieter, MD

Robert M. Strieter, MD

Strieter, Robert








Robert M. Strieter, MD


Emeritus Professor of Medicine

Fellowship: University of Michigan
Office Address: P.O. Box 800546

Division of Pulmonary and Critical Care Medicine
University of Virginia Health System
Charlottesville, VA 22908

Phone: 434-243-4845
Board Certifications: Internal Medicine
Pulmonary Disease
Critical Care Medicine
Research Interests: Cytokine and chemokine biology as related to human diseases.

Publications (selected):

Immune response CC Chemokines, CCL2 and CCL5 are associated with Pulmonary Sarcoidosis.  Palchevskiy V, Hashemi N, Weigt SS, Xue YY, Derhovanessian A, Keane MP, Strieter RM, Fishbein MC, Deng JC, Lynch JP 3rd, Elashoff R, Belperio JA.  Fibrogenesis Tissue Repair. 2011 Apr 4;4(1):10.

Overexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer.  Li A, King J, Moro A, Sugi MD, Dawson DW, Kaplan J, Li G, Lu X, Strieter RM, Burdick M, Go VL, Reber HA, Eibl G, Hines OJ.  Am J Pathol. 2011 Mar;178(3):1340-9.

The role of fibrocytes in fibrotic diseases of the lungs and heart.  Keeley EC, Mehrad B, Strieter RM. Fibrogenesis Tissue Repair. 2011 Jan 10;4:2.

Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection.  Crawford MA, Burdick MD, Glomski IJ, Boyer AE, Barr JR, Mehrad B, Strieter RM, Hughes MA.  PLoS Pathog. 2010 Nov 18;6(11):e1001199.

Chemokines as mediators of tumor angiogenesis and neovascularization.  Keeley EC, Mehrad B, Strieter RMExp Cell Res. 2011 Mar 10;317(5):685-90. Epub 2010 Oct 30.

Angiostatic and chemotactic activities of the CXC chemokine CXCL4L1 (platelet factor-4 variant) are mediated by CXCR3.  Struyf S, Salogni L, Burdick MD, Vandercappellen J, Gouwy M, Noppen S, Proost P, Opdenakker G, Parmentier M, Gerard C, Sozzani S, Strieter RM, Van Damme J.  Blood. 2011 Jan 13;117(2):480-8. Epub 2010 Oct 27.

Interferons induce CXCR3-cognate chemokine production by human metastatic melanoma.  Dengel LT, Norrod AG, Gregory BL, Clancy-Thompson E, Burdick MD, Strieter RM, Slingluff CL Jr, Mullins DW.  J Immunother. 2010 Nov-Dec;33(9):965-74.

Neutropenia enhances lung dendritic cell recruitment in response to Aspergillus via a cytokine-to-chemokine amplification loop.  Park SJ, Burdick MD, Brix WK, Stoler MH, Askew DS, Strieter RM, Mehrad B.  J Immunol. 2010 Nov 15;185(10):6190-7.

Role of LTB₄ in the pathogenesis of elastase-induced murine pulmonary emphysema.  Shim YM, Paige M, Hanna H, Kim SH, Burdick MD, Strieter RM.  Am J Physiol Lung Cell Mol Physiol. 2010 Dec;299(6):L749-59. Epub 2010 Sep 3.

V(alpha)14iNKT cells promote liver pathology during adenovirus infection by inducing CCL5 production: implications for gene therapy.  Ajuebor MN, Chen Q, Strieter RM, Adegboyega PA, Aw TY.  J Virol. 2010 Sep;84(17):8520-9. Epub 2010 Jun 23.

CXC chemokines in cancer angiogenesis and metastases.  Keeley EC, Mehrad B, Strieter RMAdv Cancer Res. 2010;106:91-111. Review.

An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells.  Lee WY, Moriarty TJ, Wong CH, Zhou H, Strieter RM, van Rooijen N, Chaconas G, Kubes P.  Nat Immunol. 2010 Apr;11(4):295-302. Epub 2010 Mar 14.

Dysregulated macrophage-inflammatory protein-2 expression drives illness in bacterial superinfection of influenza.  Zavitz CC, Bauer CM, Gaschler GJ, Fraser KM, Strieter RM, Hogaboam CM, Stampfli MR.  J Immunol. 2010 Feb 15;184(4):2001-13. Epub 2010 Jan 11.

IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury.  Li L, Huang L, Vergis AL, Ye H, Bajwa A, Narayan V, Strieter RM, Rosin DL, Okusa MD.  J Clin Invest. 2010 Jan 4;120(1):331-42. doi: 10.1172/JCI38702. Epub 2009 Dec 14.

Human circulating fibrocytes have the capacity to differentiate osteoblasts and chondrocytes.  Choi YH, Burdick MD, Strieter RMInt J Biochem Cell Biol. 2010 May;42(5):662-71. Epub 2009 Dec 23.

New mechanisms of pulmonary fibrosis.  Strieter RM, Mehrad B.  Chest. 2009 Nov;136(5):1364-70. Review.

Fibrocytes: bringing new insights into mechanisms of inflammation and fibrosis.  Keeley EC, Mehrad B, Strieter RM.  Int J Biochem Cell Biol. 2010 Apr;42(4):535-42. Epub 2009 Oct 20. Review.

The role of circulating mesenchymal progenitor cells, fibrocytes, in promoting pulmonary fibrosis.  Strieter RM, Keeley EC, Burdick MD, Mehrad B.  Trans Am Clin Climatol Assoc. 2009;120:49-59. Review.

The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis.  Strieter RM, Keeley EC, Hughes MA, Burdick MD, Mehrad B.  J Leukoc Biol. 2009 Nov;86(5):1111-8. Epub 2009 Jul 6. Review.