Jie Liu, PhD

Jie Liu, PhD

Jie Liu

Jie Liu
Degree(s): PhD
Graduate School: Shandong University (China)
Primary Appointment: Assistant Professor, Infectious Diseases and International Health
Research Interests:Molecular diagnostics and epidemiology

Email Address: jl5yj@virginia.edu

Research Description

A fundamental requirement to reduce disease burden is to discern etiologies and epidemiology to guide effective interventions such as vaccine. We aim to develop sensitive, specific, and quantitative molecular diagnostic methods for detection of causative agents, including viruses, bacteria, and parasites. Then we apply these methods to studies in various settings, such as case/control, birth cohort, or surveillance, to assess the regional/global burden of these agents and more importantly identify their association with diseases. Meanwhile, these methods are also being used in intervention studies to measure the effectiveness of a prevention or treatment procedure.

Selected Publications

Liu J, Kabir F, Manneh J, Lertsethtakarn P, Begum S, Gratz J, Becker SM, Operario DJ, Taniuchi M, Janaki L, Platts-Mills JA, Haverstick DM, Kabir M, Sobuz SU, Nakjarung K, Sakpaisal P, Silapong S, Bodhidatta L, Qureshi S, Kalam A, Saidi Q, Swai N, Mujaga B, Maro A, Kwambana B, Dione M, Antonio M, Kibiki G, Mason CJ, Haque R, Iqbal N, Zaidi AK, Houpt ER.  Development and assessment of molecular diagnostic tests for 15 enteropathogens causing childhood diarrhoea: a multicentre study.  Lancet Infect Dis. 2014 Aug;14(8):716-24. doi: 10.1016/S1473-3099(14)70808-4. Epub 2014 Jul 9.

Platts-Mills JA, Liu J, Gratz J, Mduma E, Amour C, Swai N, Taniuchi M, Begum S, Peñataro Yori P, Tilley DH, Lee G, Shen Z, Whary MT, Fox JG, McGrath M, Kosek M, Haque R, Houpt ER.  Detection of Campylobacter in stool and determination of significance by culture, enzyme immunoassay, and PCR in developing countries.  J Clin Microbiol. 2014 Apr;52(4):1074-80. doi: 10.1128/JCM.02935-13. Epub 2014 Jan 22.

Liu J, Winstead-Derlega C, Houpt E, Heidkamp R, Pape J, Dillingham R.  Pre-earthquake non-epidemic Vibrio cholerae in Haiti.  J Infect Dev Ctries. 2014 Jan 15;8(1):120-2. doi: 10.3855/jidc.4524.

Platts-Mills JA, Gratz J, Mduma E, Svensen E, Amour C, Liu J, Maro A, Saidi Q, Swai N, Kumburu H, McCormick BJ, Kibiki G, Houpt ER.  Association between stool enteropathogen quantity and disease in Tanzanian children using TaqMan array cards: a nested case-control study.  Am J Trop Med Hyg. 2014 Jan;90(1):133-8. doi: 10.4269/ajtmh.13-0439. Epub 2013 Nov 4.

Liu J, Gratz J, Amour C, Kibiki G, Becker S, Janaki L, Verweij JJ, Taniuchi M, Sobuz SU, Haque R, Haverstick DM, Houpt ER.  A laboratory-developed TaqMan Array Card for simultaneous detection of 19 enteropathogens.  J Clin Microbiol. 2013 Feb;51(2):472-80. doi: 10.1128/JCM.02658-12. Epub 2012 Nov 21.

Liu J, Gratz J, Maro A, Kumburu H, Kibiki G, Taniuchi M, Howlader AM, Sobuz SU, Haque R, Talukder KA, Qureshi S, Zaidi A, Haverstick DM, Houpt ER.  Simultaneous detection of six diarrhea-causing bacterial pathogens with an in-house PCR-luminex assay.  J Clin Microbiol. 2012 Jan;50(1):98-103. doi: 10.1128/JCM.05416-11. Epub 2011 Nov 9.

PubMed Listings for this Faculty Member

Contact Information

Office Address:

PO Box 801340;Carter Harrison Building, Rm 1712A,
345 Crispell Drive, Charlottesville

Office Phone:

+1 434-243-8074

Office Fax:

+1 434-924-0075