Molly A. Hughes, MD, PhD

Molly A. Hughes, MD, PhD

Molly  A.  Hughes
Degree(s): MD, PhD
Graduate School: Vanderbilt University
Primary Appointment: Associate Professor, Medicine, Infectious Diseases and International Health
Research Interests:
Biodefense and emerging pathogens
Email Address: mah3x@virginia.edu

Research Description

Biodefense and emerging pathogens.


Selected Publications

Crawford MA, Lowe DE, Fisher DJ, Stibitz S, Plaut RD, Beaber JW, Zemansky J, Mehrad B, Glomski IJ, Strieter RM, Hughes MA.  Identification of the bacterial protein FtsX as a unique target of chemokine-mediated antimicrobial activity against Bacillus anthracis. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17159-64. doi: 10.1073/pnas.1108495108. Epub 2011 Sep 26.

Crawford MA, Burdick MD, Glomski IJ, Boyer AE, Barr JR, Mehrad B, Strieter RM, Hughes MA.  Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection. PLoS Pathog. 2010 Nov 18;6(11):e1001199. doi: 10.1371/journal.ppat.1001199.

Hughes MA, Burns DL, Juris SJ, Tang WJ, Clement KH, Eaton LJ, Kelly-Cirino CD, McKee ML, Powell BS, Bishop BL, Rudge TL, Shine N, Verma A, Willis MS, Morse SA.  The case for developing consensus standards for research in microbial pathogenesis: Bacillus anthracis toxins as an example. Infect Immun. 2009 Oct;77(10):4182-6. doi: 10.1128/IAI.00368-09. Epub 2009 Aug 3. No abstract available.

Strieter RM, Keeley EC, Hughes MA, Burdick MD, Mehrad B.  The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis. J Leukoc Biol. 2009 Nov;86(5):1111-8. doi: 10.1189/jlb.0309132. Epub 2009 Jul 6. Review.

Park SJ, Hughes MA, Burdick M, Strieter RM, Mehrad B.  Early NK cell-derived IFN-{gamma} is essential to host defense in neutropenic invasive aspergillosis. J Immunol. 2009 Apr 1;182(7):4306-12. doi: 10.4049/jimmunol.0803462.

Crawford MA, Zhu Y, Green CS, Burdick MD, Sanz P, Alem F, O'Brien AD, Mehrad B, Strieter RM, Hughes MA.  Antimicrobial effects of interferon-inducible CXC chemokines against Bacillus anthracis spores and bacilli. Infect Immun. 2009 Apr;77(4):1664-78. doi: 10.1128/IAI.01208-08. Epub 2009 Jan 29.

PubMed Listings for this Faculty Member


Contact Information
Office Address: Box 800513 MR-6, 345 Crispell Dr. Room 1704A,
Office Phone: +1 434-924-5216, +1 434-924-5267
Fax Phone: +1 434-924-0075