Eric R. Houpt, MD
Graduate School: Emory University
Primary Appointment: Jack Gwaltney Professor of Medicine, Infectious Diseases and International Health
Molecular diagnostics and Immunology
Email Address: firstname.lastname@example.org
Our laboratory is involved in several projects largely focused on molecular diagnostic tools for infectious diseases. Most work involves developing panels of PCR-based diagnostic tests to detect a full range of enteropathogens, and we utilize these tests at our collaborative field sites in Tanzania and Bangladesh and several other global sites in the context of clinical research. In Tanzania we have laboratories both at the Kilimanjaro Christian Medical Centre in Moshi and a new field site in rural Haydom. We have a program on tuberculosis, both on developing rapid diagnostics that can identify which drugs to use for multidrug resistant Tb, as well as identifying markers for slow response to therapy.
Lima IF, Quetz JD, Guerrant RL, Nataro JP, Houpt ER, Lima AA, Havt A. Enteroaggregative Escherichia coli quantification in children stool samples using quantitative PCR . APMIS. 2012 Dec 6. doi: 10.1111/apm.12032. [Epub ahead of print]
Panchalingam S, Antonio M, Hossain A, Mandomando I, Ochieng B, Oundo J, Ramamurthy T, Tamboura B, Zaidi AK, Petri W, Houpt E, Murray P, Prado V, Vidal R, Steele D, Strockbine N, Sansonetti P, Glass RI, Robins-Browne RM, Tauschek M, Svennerholm AM, Kotloff K, Levine MM, Nataro JP. Diagnostic Microbiologic Methods in the GEMS-1 Case/Control Study. Clin Infect Dis. 2012 Dec;55 Suppl 4:S294-302. doi: 10.1093/cid/cis754.
Liu J, Gratz J, Amour C, Kibiki G, Becker S, Janaki L, Verweij JJ, Taniuchi M, Sobuz SU, Haque R, Haverstick DM, Houpt ER. A Laboratory Developed TaqMan Array Card for Simultaneous Detection of Nineteen Enteropathogens. J Clin Microbiol. 2012 Nov 21. [Epub ahead of print]
Nelson AM, Walk ST, Taube S, Taniuchi M, Houpt ER, Wobus CE, Young VB. Disruption of the human gut microbiota following Norovirus infection. PLoS One. 2012;7(10):e48224. doi: 10.1371/journal.pone.0048224. Epub 2012 Oct 30.
Shimokawa C, Kabir M, Taniuchi M, Mondal D, Kobayashi S, Ali IK, Sobuz SU, Senba M, Houpt E, Haque R, Petri WA Jr, Hamano S. Entamoeba moshkovskii is associated with diarrhea in infants and causes diarrhea and colitis in mice. J Infect Dis. 2012 Sep 1;206(5):744-51. doi: 10.1093/infdis/jis414. Epub 2012 Jun 21.
Heysell SK, Houpt ER. The future of molecular diagnostics for drug-resistant tuberculosis. Expert Rev Mol Diagn. 2012 May;12(4):395-405. doi: 10.1586/erm.12.25. Review.
Mpagama SG, Mtabho C, Mwaigwisya S, Mleoh LJ, Boer IM, Heysell SK, Houpt ER, Kibiki GS. Comparison of overnight pooled and standard sputum collection method for patients with suspected pulmonary tuberculosis in northern Tanzania. Tuberc Res Treat. 2012;2012:128057. doi: 10.1155/2012/128057. Epub 2012 Jan 19.