Kevin C. Hazen, PhD

Kevin C. Hazen, PhD

Kevin  C.  Hazen
Degree(s): PhD
Graduate School: Montana State University
Primary Appointment: Professor, Pathology
Research Interests:
Fungal pathogenesis. Fungal surface proteins and hydrophobicity.
Email Address: kch7y@virginia.edu

Research Description

Fungal pathogenesis. Fungal surface proteins and hydrophobicity. My laboratory is concerned with the biochemistry and molecular biology of surface hydrophobic protein expression of medically important fungi, especially Candida. We are also interested in characterizing the role and regulation of surface protein glycosylation as it affects surface hydrophobins (hydrophobic adhesins) interactions with host and prosthetic surfaces. The role of surface hydrophobic proteins in tissue specific adhesion by Candida sp. is also under investigation. Biochemical, molecular genetics, biophysical and histological methods are used in our studies.


Selected Publications

Shah AA, Hazen KC.  Diagnostic accuracy of histopathologic and cytopathologic examination of Aspergillus species. Am J Clin Pathol. 2013 Jan;139(1):55-61. doi: 10.1309/AJCPO8VTSK3HRNUT.

Hazen KC.  Influence of DMSO on antifungal activity during susceptibility testing in vitro. Diagn Microbiol Infect Dis. 2013 Jan;75(1):60-3. doi: 10.1016/j.diagmicrobio.2012.09.002. Epub 2012 Oct 6.

Mathers AJ, Hazen KC, Carroll J, Yeh AJ, Cox HL, Bonomo RA, Sifri CD.  First Clinical Cases of OXA-48 Producing Carbapenem Resistant Klebsiella pneumoniae in the United States: the "menace" arrives in the New World. J Clin Microbiol. 2012 Nov 21. [Epub ahead of print]

Mathers AJ, Cox HL, Kitchel B, Bonatti H, Brassinga AK, Carroll J, Scheld WM, Hazen KC, Sifri CD.  Molecular dissection of an outbreak of carbapenem-resistant enterobacteriaceae reveals Intergenus KPC carbapenemase transmission through a promiscuous plasmid. MBio. 2011 Nov 1;2(6):e00204-11. doi: 10.1128/mBio.00204-11. Print 2011.

PubMed Listings for this Faculty Member


Contact Information
Office Address: PO Box 800904, MR-5, Room 3129,
Office Phone: 434-924-8067, 434-924-8061
Fax Phone: 434-924-2151