Joshua C. Eby, MD

Joshua C. Eby, MD

J Eby
Joshua  C.  Eby
Degree(s): MD
Graduate School: Stanford University
Primary Appointment: Associate Professor, Medicine, Infectious Diseases and International Health
Research Interests:
Pathogenesis of Bordetella pertussis infection. Interaction of bacterial protein toxins with host target cells. Clinical diagnostics for adult and pediatric pertussis.
Email Address: jce4u@virginia.edu

Research Description

Pathogenesis of Bordetella pertussis infection. Interaction of bacterial protein toxins with host target cells. Clinical diagnostics for adult and pediatric pertussis.


Selected Publications

Donato GM, Goldsmith CS, Paddock CD, Eby JC, Gray MC, Hewlett EL.  Delivery of Bordetella pertussis adenylate cyclase toxin to target cells via outer membrane vesicles. FEBS Lett. 2012 Feb 17;586(4):459-65. doi: 10.1016/j.febslet.2012.01.032. Epub 2012 Jan 28.

Eby JC, Gray MC, Mangan AR, Donato GM, Hewlett EL.  Role of CD11b/CD18 in the process of intoxication by the adenylate cyclase toxin of Bordetella pertussis. Infect Immun. 2012 Feb;80(2):850-9. doi: 10.1128/IAI.05979-11. Epub 2011 Dec 5.

Eby JC, Ciesla WP, Hamman W, Donato GM, Pickles RJ, Hewlett EL, Lencer WI. Selective translocation of the Bordetella pertussis adenylate cyclase toxin across the basolateral membranes of polarized epithelial cells. J Biol Chem. 2010 Apr 2;285(14):10662-70. doi: 10.1074/jbc.M109.089219.  Epub 2010 Feb 5.

PubMed Link for this Faculty Member


Contact Information
Office Address: PO Box 800419,
Office Phone: 434-924-0982