Michael O. Thorner, MB, DSc

Michael O. Thorner, MB, DSc

null Michael  O.  Thorner
Degree(s): MBBS, DSc, FACP, FRCP
Graduate School: University of London
Primary Appointment: David C. Harrison Medical Teaching Professor of Internal Medicine
Research Interests:

Endocrinology and metabolism, specifically neuroendocrinology and hypothalamic pituitary disease

Email Address: mot@virginia.edu

Research Description

Endocrinology and metabolism, specifically neuroendocrinology and hypothalamic pituitary disease.


Selected Publications

Kelly BN, Haverstick DM, Vance ML, Thorner MO, Bruns DE. Quantification of growth hormone mRNA in blood. Clin Chim Acta. 2012 Dec 24;414:206-10. doi: 10.1016/j.cca.2012.09.011. Epub 2012 Sep 15. PubMed PMID: 22985689.

Jane JA Jr, Starke RM, Elzoghby MA, Reames DL, Payne SC, Thorner MO, Marshall JC, Laws ER Jr, Vance ML. Endoscopic transsphenoidal surgery for acromegaly: remission using modern criteria, complications, and predictors of outcome. J Clin Endocrinol Metab. 2011 Sep;96(9):2732-40. doi: 10.1210/jc.2011-0554. Epub 2011 Jun 29. PubMed PMID: 21715544.

Nass R, Gaylinn BD, Thorner MO. The role of ghrelin in GH secretion and GH disorders. Mol Cell Endocrinol. 2011 Jun 20;340(1):10-4. doi: 10.1016/j.mce.2011.03.021. Epub 2011 Apr 1. Review. PubMed PMID: 21459126.

Nass R, Gaylinn BD, Thorner MO. The ghrelin axis in disease: potential therapeutic indications. Mol Cell Endocrinol. 2011 Jun 20;340(1):106-10. doi: 10.1016/j.mce.2011.02.010. Epub 2011 Feb 25. Review. PubMed PMID: 21356273; PubMed Central PMCID: PMC3114265.

Bush ZM, Longtine JA, Cunningham T, Schiff D, Jane JA Jr, Vance ML, Thorner MO, Laws ER Jr, Lopes MB. Temozolomide treatment for aggressive pituitary tumors: correlation of clinical outcome with O(6)-methylguanine methyltransferase (MGMT) promoter methylation and expression. J Clin Endocrinol Metab. 2010 Nov;95(11):E280-90. doi: 10.1210/jc.2010-0441. Epub 2010 Jul 28. PubMed PMID: 20668043.

Larner J, Brautigan DL, Thorner MO. D-chiro-inositol glycans in insulin signaling and insulin resistance. Mol Med. 2010 Nov-Dec;16(11-12):543-52. doi: 10.2119/molmed.2010.00107. Epub 2010 Aug 27. Review. PubMed PMID: 20811656; PubMed Central PMCID: PMC2972396.

Nass RM, Gaylinn BD, Rogol AD, Thorner MO. Ghrelin and growth hormone: story in reverse. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8501-2. doi: 10.1073/pnas.1002941107. Epub 2010 Apr 30. PubMed PMID: 20435917; PubMed Central  PMCID: PMC2889295.

Prudom C, Liu J, Patrie J, Gaylinn BD, Foster-Schubert KE, Cummings DE, Thorner MO, Geysen HM. Comparison of competitive radioimmunoassays and two-site sandwich assays for the measurement and interpretation of plasma ghrelin levels. J Clin Endocrinol Metab. 2010 May;95(5):2351-8. doi:1210/jc.2009-2407. Epub 2010 Mar 1. PubMed PMID: 20194708; PubMed Central PMCID: PMC2869544.

Thorner MO. Statement by the Growth Hormone Research Society on the GH/IGF-I axis in extending health span. J Gerontol A Biol Sci Med Sci. 2009 Oct;64(10):1039-44. doi: 10.1093/gerona/glp091. Epub 2009 Jul 8. PubMed PMID: 19587105.

Nass R, Johannsson G, Christiansen JS, Kopchick JJ, Thorner MO. The aging population--is there a role for endocrine interventions? Growth Horm IGF Res. 2009 Apr;19(2):89-100. doi: 10.1016/j.ghir.2008.09.002. Epub 2008 Nov 1. Review.  PubMed PMID: 18977675.

PubMed Listings for this Faculty Member


Contact Information

Office Address: PO Box 801411 450 Ray C. Hunt Dr. Aurbach Bldg,

Office Phone: +1 434-982-3297

Fax Phone: +1 434-979-4967