Shetal H. Padia, MD

Shetal H. Padia, MD

null Shetal  H.  Padia
Degree(s): MD
Graduate School: Brody School of Medicine, East Carolina University
Primary Appointment: Assistant Professor, Medicine, Endocrinology and Metabolism
Research Interests:
Hypertension, obesity, ghrelin, and the renin-angiotensin system.
Email Address: shp6a@Virginia.edu

Research Description

Hypertension; renal receptors involved in salt and water reabsorption; ghrelin receptors; renin-angiotensin system; AT1 and AT2 receptors; natriuresis; aminopeptidases.


Selected Publications

Carey RM, Padia SH. Role of angiotensin at(2) receptors in natriuresis:intrarenal mechanisms and therapeutic potential. Clin Exp Pharmacol Physiol. 2013 Jan 22. doi: 10.1111/1440-1681.12059. [Epub ahead of print] PubMed PMID: 23336117.

Padia SH, Carey RM. AT2 receptors: beneficial counter-regulatory role incardiovascular and renal function. Pflugers Arch. 2013 Jan;465(1):99-110. doi: 10.1007/s00424-012-1146-3. Epub 2012 Sep 5. PubMed PMID: 22949090; PubMed Central PMCID: PMC3548020.

Kemp BA, Bell JF, Rottkamp DM, Howell NL, Shao W, Navar LG, Padia SH, Carey RM. Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors. Hypertension. 2012 Aug;60(2):387-95. doi:
10.1161/HYPERTENSIONAHA.112.191403. Epub 2012 Jun 11. PubMed PMID: 22689743.

Padia SH, Kemp BA, Howell NL, Keller SR, Gildea JJ, Carey RM. Mechanisms of dopamine D(1) and angiotensin type 2 receptor interaction in natriuresis. Hypertension. 2012 Feb;59(2):437-45. doi: 10.1161/HYPERTENSIONAHA.111.184788. Epub 2011 Dec 27. PubMed PMID: 22203736; PubMed Central PMCID: PMC3279722.

Kemp BA, Howell NL, Gray JT, Keller SR, Nass RM, Padia SH. Intrarenal ghrelin infusion stimulates distal nephron-dependent sodium reabsorption in normal rats. Hypertension. 2011 Mar;57(3):633-9. doi: 10.1161/HYPERTENSIONAHA.110.166413. Epub 2011 Jan 10. PubMed PMID: 21220707; PubMed Central PMCID: PMC3041845.

Padia SH, Howell NL, Kemp BA, Fournie-Zaluski MC, Roques BP, Carey RM. Intrarenal aminopeptidase N inhibition restores defective angiontesin II type 2-mediated natriuresis in spontaneously hypertensive rats. Hypertension. 2010 Feb;55(2):474-80. doi: 10.1161/HYPERTENSIONAHA.109.144956. Epub 2009 Dec 7. PubMed PMID: 19996063; PubMed Central PMCID: PMC2809800.

Padia SH, Kemp BA, Howell NL, Gildea JJ, Keller SR, Carey RM. Intrarenal angiotensin III infusion induces natriuresis and angiotensin type 2 receptor translocation in Wistar-Kyoto but not in spontaneously hypertensive rats. Hypertension. 2009 Feb;53(2):338-43. doi: 10.1161/HYPERTENSIONAHA.108.124198. Epub 2008 Dec 15. PubMed PMID: 19075092; PubMed Central PMCID: PMC2677704.

Carey RM, Padia SH. Angiotensin AT2 receptors: control of renal sodium excretion and blood pressure. Trends Endocrinol Metab. 2008 Apr;19(3):84-7. doi: 10.1016/j.tem.2008.01.003. Epub 2008 Feb 21. Review. PubMed PMID: 18294862.

Padia SH, Kemp BA, Howell NL, Fournie-Zaluski MC, Roques BP, Carey RM. Conversion of renal angiotensin II to angiotensin III is critical for AT2 receptor-mediated natriuresis in rats. Hypertension. 2008 Feb;51(2):460-5. Epub 2007 Dec 24. PubMed PMID: 18158338.

Padia SH, Kemp BA, Howell NL, Siragy HM, Fournie-Zaluski MC, Roques BP, Carey RM. Intrarenal aminopeptidase N inhibition augments natriuretic responses to angiotensin III in angiotensin type 1 receptor-blocked rats. Hypertension. 2007 Mar;49(3):625-30. Epub 2006 Dec 26. PubMed PMID: 17190872.

PubMed Publications for the Author


Contact Information

Office Address: PO Box 801414
Charlottesville, VA 22908-1414

Office Phone: 434-924-8125

Office Fax: 434-982-3626