Robert M. Carey, MD

Robert M. Carey, MD

null Robert  M.  Carey
Degree(s): MD, MACP
Graduate School:  Vanderbilt University
Primary Appointment: Dean Emeritus and Harrison Distinguished Professor of Medicine; Professor, Medicine, Endocrinology and Metabolism
Research Interests:
Hormonal regulation of the cardiovascular and renal systems; regulation of blood pressure; intrarenal dopaminergic and renin-angiotensin systems.
Website: http://www.healthsystem.virginia.edu/internet/carey/
Email Address: rmc4c@virginia.edu

Research Description

Dr. Carey's research is aimed at understanding the pathophysiologic mechanisms of hypertension. He studies the function of dopamine and angiotensin receptors in the kidney, heart, and peripheral blood vessels. His laboratory has pioneered the discovery of the function of renal D1-like receptors and angiotensin AT2 receptors.

Current projects include studying the role of AT2 receptors in sodium excretion and hypertension; the interaction of dopamine receptors with angiotensin receptors within the kidney; the role of extracellular renal cyclic GMP in pressure-natriuresis; and the role of urinary angiotensinogen as a marker for activation of the intrarenal renin-angiotensin system. Dr. Carey is a world renowned cardiovascular endocrinologist, and is currently president of The Endocrine Society.


Selected Publications

Carey RM. The intrarenal Renin-Angiotensin and dopaminergic systems: control of renal sodium excretion and blood pressure. Hypertension. 2013 Mar;61(3):673-80. doi: 10.1161/HYPERTENSIONAHA.111.00241. PubMed PMID: 23407646; PubMed Central PMCID: PMC3577093.

Carey RM. Resistant Hypertension. Hypertension. 2013 Feb 25. [Epub ahead of print] PubMed PMID: 23438928.

Carey RM, Padia SH. Role of angiotensin at(2) receptors in natriuresis:intrarenal mechanisms and therapeutic potential. Clin Exp Pharmacol Physiol. 2013 Jan 22. doi: 10.1111/1440-1681.12059. [Epub ahead of print] PubMed PMID: 23336117.

Padia SH, Carey RM. AT(2) receptors: beneficial counter-regulatory role in cardiovascular and renal function. Pflugers Arch. 2013 Jan;465(1):99-110. doi: 10.1007/s00424-012-1146-3. Epub 2012 Sep 5. PubMed PMID: 22949090; PubMed Central PMCID: PMC3548020.

Carey RM, Schoeffel CD, Gildea JJ, Jones JE, McGrath HE, Gordon LN, Park MJ, Sobota RS, Underwood PC, Williams J, Sun B, Raby B, Lasky-Su J, Hopkins PN, Adler GK, Williams SM, Jose PA, Felder RA. Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter. Hypertension. 2012 Nov;60(5):1359-66. doi: 10.1161/HYPERTENSIONAHA.112.196071. Epub 2012 Sep 17. PubMed PMID: 22987918; PubMed Central PMCID: PMC3495588.

Carey RM. Primary aldosteronism. J Surg Oncol. 2012 Oct 1;106(5):575-9. doi: 10.1002/jso.23206. Epub 2012 Jul 17. Review. PubMed PMID: 22806599.

Gildea JJ, Wang X, Shah N, Tran H, Spinosa M, Van Sciver R, Sasaki M, Yatabe J, Carey RM, Jose PA, Felder RA. Dopamine and angiotensin type 2 receptors cooperatively inhibit sodium transport in human renal proximal tubule cells. Hypertension. 2012 Aug;60(2):396-403. doi: 10.1161/HYPERTENSIONAHA.112.194175. Epub 2012 Jun 18. Erratum in: Hypertension. 2013 Jan;61(1):e7. PubMed PMID: 22710646; PubMed Central PMCID: PMC3406928.

Kemp BA, Bell JF, Rottkamp DM, Howell NL, Shao W, Navar LG, Padia SH, Carey RM. Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors. Hypertension. 2012 Aug;60(2):387-95. doi:10.1161/HYPERTENSIONAHA.112.191403. Epub 2012 Jun 11. PubMed PMID: 22689743.

Bailey AP, Schutt AK, Carey RM, Angle JF, Modesitt SC. Hyperandrogenism of ovarian etiology: utilizing differential venous sampling for diagnosis. Obstet Gynecol. 2012 Aug;120(2 Pt 2):476-9. doi: 10.1097/AOG.0b013e31825a711c. PubMed PMID: 22825271.

Guagliardo NA, Yao J, Hu C, Schertz EM, Tyson DA, Carey RM, Bayliss DA, Barrett PQ. TASK-3 channel deletion in mice recapitulates low-renin essential hypertension. Hypertension. 2012 May;59(5):999-1005. doi: 10.1161/ HYPERTENSIONAHA.111.189662. Epub 2012 Apr 9. Erratum in: Hypertension. 2012 Jun;59(6):e59. PubMed PMID: 22493079; PubMed Central PMCID: PMC3357084.

PubMed Listings for this Faculty Member


Contact Information

Office Address: P.O. Box 801414 Charlottesville, VA 22908-1414

Office Phone: 434-924-5510

Fax Phone: 434-982-3626

Web Site: http://www.healthsystem.virginia.edu/carey