Research in Anesthesiology

Research in Anesthesiology

Research, both clinical and basic, is an essential part of the field of anesthesiology, and is the road by which the specialty progresses. It is therefore also an essential part of the mission of the Department of Anesthesiology.

Basic Science

The Department of Anesthesiology maintains an active program of basic science research in mechanisms of anesthetics.  Three faculty members (Drs. Jevtovic-Todorovic, Todorovic, and Zuo) who hold both the M.D. and Ph.D. degrees are active as clinical anesthesiologists, while devoting the majority of their time to responsibilities as principal investigators directing NIH-funded research labs. 

Two other clinical anesthesiologists (Drs. Lynch and Raphael) have primary responsibilities as clinicians while maintaining significant research commitments.  Dr. Lynch holds both the M.D. and Ph.D. degrees.  Drs. Nadia Lunardi and Christine Zanghi are our newest clinician investigators.  Each holds both an M.D. and a Ph.D. degree and will commit substantial time to basic research while also carrying a clinical load.

Of our Ph.D. researchers, Dr. Patel has a full-time commitment to research in anesthesiology.  Two researchers (Drs. Bayliss and Palmer) maintain primary affiliation with other departments and hold secondary appointments in Anesthesiology.

The overall focus of the basic research effort of the Department is neuroscience and anesthesia. Although the time required to learn research-specific techniques limits the ability of residents to participate in basic research, some residents have done so, presenting and publishing their research results. For dedicated trainees (particularly those with prior basic science experience), opportunities can be created.

For more information about our basic science laboratories and principal investigators, visit their research pages or contact them directly:


Clinical Research

The clinical research program is broader in scope, reflecting the diverse interests of the faculty. Also, a wide variety of types of clinical research is performed, ranging from participation in large multi-center trials (currently POISE-2, for example) to small faculty-initiated projects funded through departmental accounts. Overall, several dozen trials are active at any time, overseen by the departmental Clinical Research Committee.

This wide-ranging clinical research program offers excellent opportunities for resident participation, not only in data collection, but also in research design, analysis, and presentation. The department is also open to resident-initiated clinical trials, and many research ideas, proposed and brought to completion by residents, have led to publications.

Technology in Anesthesia and Critical Care

Under the direction of Dr. Robert Thiele, the Technology in Anesthesia and Critical Care Group includes researchers from the School of Medicine and the School of Engineering and Applied Sciences who share an interest in biomedical devices.