BIMS 6000 -- Core Course in Integrative Biosciences

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BIMS 6000 -- Core Course in Integrative Biosciences

Class schedule

Block 0

CCIB Orientation

Day 1

Orientation

Day 2

Orientation

Day 3

Orientation

Block 1

Protein Structure

Day 1

Amino acids and polypeptides

Day 2

Protein folding and interactions

Day 3

Protein evolution and similarities

Day 4

Protein domains  and structure determination

Day 5

Macromolecular X-ray crystallography

Day 6

Proteins and structure

Day 7

SNP Symposium

Block 2

Genome Architecture and Stability

Day 1

DNA and Chromatin Structure

Day 2

Chromatin Regulation

Day 3

Chromosome Organization

Day 4

Analyzing DNA and Genome Variation

Day 5

DNA Replication

Day 6

DNA Repair

Block 3

Genetic Information Flow

Day 1

Nucleus and Gene Expression

Day 2

Regulation of Transcription

Day 3

Silencing, Imprinting & Insulators

Day 4

Translation: from RNA to Protein

Day 5

RNA Processing & Trafficking

Day 6

Regulation of Genetic Information Flow

Block 4

Genetics

Day 1

Genetics as an experimental tool in model organisms

Day 2

Forward genetic screens and modern techniques to expand the genetics toolbox

Block 5

Membranes and Cell Compartments

Day 1

Membrane Organization

Day 2

Protein Translocation

Day 3

ER Function and Unfolded Protein Response

Day 4

Class Discussion

Day 5

Class Discussion

Day 6

Class Discussion

Block 6-1

Part I: Excitable  Membranes and Neuronal Signaling

Day 1

Channels,Currents & Potentials

Day 2

Neuronal Physiology and Networks

Block 6-2

Part 2:  Cell Signaling – Pathways and Effector

Day 3

GPCRs and Signaling

Day 4

Signaling by Tyr Kinase Receptors

Day 5

Kinase Inhibitors & Enzyme Kinetics

Day 6

Steroid Nuclear Receptors and Cellular Actions

Day 7

Applying the Principles of Signaling

Block 7

Metabolism

Day 1

Glucose, etc.

Day 2

Metabolomics, etc.

Day 3

Insulin, etc.

Block 8

Cytoskeleton, Cell Adhesion and Migration

Day 1

Introduction to the Cytoskeleton

Day 2

Single Cell Migration and Cell-ECM Interactions

Day 3

Cell-ECM Adhesion and Integrin Signaling

Day 4

Cell-Cell Adhesion and Junctions

Day 5

Wrap-Up Session

Block 9

Cell Cycle and Mitosis

Day 1

The Cell Cycle

Day 2

Cell Cycle Regulation and Mitosis

Day 3

Cell Proliferation and Cancer

Block 10

Integrating Cells into Tissues: Development, Disease & Regeneration

Day 1

Tissue Organization – Development, Form and Function

Day 2

Intestinal Morphogenesis and Colorectal Cancer

Day 3

Neurogenesis and Brain Growth

Day 4

Regeneration and Stem Cells

Day 5

Wrap-Up, CCIB-Associated Special Seminar