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Welcome to the Park Lab

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Our overarching goal is to develop novel strategies for targeted therapy as well as early detection and prevention through understanding the mechanisms of SCLC development. To this end, we developed and used a genetically engineered mouse model that recapitulates the genetic alterations apparent in human small cell lung cancer (SCLC). Using this mouse model, we interrogated molecular and cellular mechanisms that drive SCLC initiation, progression, and maintenance. [more]