Selected Publications

  • Zhang Y, Anderson S, French S, Sikes M, Viktorovskaya O, Huband J, Holcomb K, Hartman J, Beyer A, Schneider D. The SWI/SNF chromatin remodeling complex influences transcription by RNA polymerase I in Saccharomyces cerevisiae. PloS one. 2013;8(2): e56793. PMID: 23437238


  • Viktorovskaya O, Engel K, French S, Cui P, Vandeventer P, Pavlovic E, Beyer A, Kaplan C, Schneider D. Divergent contributions of conserved active site residues to transcription by eukaryotic RNA polymerases I and II. Cell reports. 2013;4(5): 974-84. PMID: 23994471


  • Lebaron S, Segerstolpe A, French S, Dudnakova T, de Lima Alves F, Granneman S, Rappsilber J, Beyer A, Wieslander L, Tollervey D. Rrp5 Binding at Multiple Sites Coordinates Pre-rRNA Processing and Assembly. Molecular cell. 2013.PMID: 24239293


  • Johnson J, French S, Osheim Y, Li M, Hall L, Beyer A, Smith J. Rpd3- and spt16-mediated nucleosome assembly and transcriptional regulation on yeast ribosomal DNA genes. Molecular and cellular biology. 2013;33(14): 2748-59.PMID: 23689130


  • French SL, Sikes ML, Hontz RD, Osheim YN, Lambert TE, El Hage A, Smith MM, Tollervey D, Smith JS, Beyer AL. (2011) Distinguishing the roles of Topoisomerase I and II in relief of transcription-induced supercoiling in yeast rDNA genes. Mol Cell Biol. 31(3):482-494.


  • El Hage A, French SL, Beyer AL, Tollervey D. (2010) Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis.  Genes Dev. 24(14):1546-1558.


  • Lundkvist P, Jupiter S, Segerstolpe A, Osheim YN, Beyer AL, Wieslander L. (2009) Mrd1p is required for release of base-paired U3 snoRNA within the preribosomal complex. Mol Cell Biol. 29(21):5763-5774.



  • Hontz RD, French SL, Oakes ML, Tongaonkar P, Nomura M, Beyer AL, Smith JS. (2008) Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30. Mol Cell Biol. 28(21):6709-6719.


  • French SL, Osheim YN, Schneider DA, Sikes ML, Fernandez CF, Copela LA, Misra VA, Nomura M, Wolin SL, Beyer AL. (2008) Visual analysis of the yeast 5S rRNA gene transcriptome: regulation and role of La protein. Mol Cell Biol. 28(14):4576-4587.


Our EM method:

  • Osheim YN, French SL, Sikes ML, Beyer AL. (2009) Electron microscope visualization of RNA transcription and processing in Saccharomyces cerevisiae by Miller chromatin spreading. Methods Mol Biol. 464:55-69.