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MIC News
| MIC AWARDS - NEWS - EVENTS 2013 |
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A group of undergraduates mentored by faculty members and a graduate
student from the Thaler Center have been awarded a Jefferson Public
Citizens (JPC) Award in support of their project "Outreach Biology
Education Modules for Secondary School Learners in Limpopo Province,
South Africa" JPC is the premier UVa community outreach program for
undergraduates. They are providing $44,000 for the project.
The students will work in the Thaler Center this Spring developing
the lab exercises and other teaching materials, then go to South Africa
this summer for seven weeks to implement what they have planned. In
South Africa, the UVA students will interact and transfer their
"know-how" to University of Venda students and also teach the high
school students directly for several weeks.
JPC Group:
Walter
Hodges, Heather Lee, Joo Yung Lee, Jason Liao
Faculty
Advisors: David
Rekosh, Marie-Louise Hammarskjöld, Adrienne Keller
Graduate
Mentor: Siripong
Tongjai
Community
Partner: Vuwani
Science Research Center
Project
Title: Outreach
Biology Education Modules for Secondary School Learners in Limpopo
Province in South Africa
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| MIC AWARDS - NEWS - EVENTS 2012 |
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2012 MIC Poster Contest - Congratulations to David Brautigan,
Mariette Babier, Cassandra Hoffman, Alexander Kofman and David Kashatus
for winning entries in the competition. [read more] |
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New MIC Faculty: We welcome Melissa Kendall, PhD
In her new laboratory at UVA (located in Jordan 7212), Melissa will
focus on understanding the regulatory cascade involved in ethanolamine
(EA) metabolism and virulence gene expression in EHEC. Ethanoloamine is
present in the large intestine due to the turnover of intestinal cells
as well as through the host diet. EHEC uses EA as a nitrogen source and
thus gains a competitive advantage for colonization over the indigenous
microbiota. Her recent exciting has shown that EA is not only important
for nitrogen metabolism, but can signal to activate genes involved in
inter-‐kingdom signaling, type three secretion, and Shiga toxin
production (Kendall et al., 2012). Further understanding of this
regulatory system will lead to the identification of novel virulence
factors and may lead to the development of anti-‐virulence therapies.
[
more]
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New MIC Faculty: We welcome David
Kashatus, PhD
In his new laboratory here at UVA
(located in Jordan 7022), Dave will focus on the role of mitochondrial
dynamics in tumorigenesis. Since mitochondrial fusion and fission are
increasingly recognized to affect metabolism, autophagy and
apoptosis, a key focus of his new laboratory will be to elucidate how
key oncogenic signaling pathways interact with the mitochondrial
fusion and fission machinery and how they impact mitochondrial
morphology and mitochondrial function. He also plans to use mouse
models of cancer to ask whether mitochondrial dynamics plays a role in
tumorigenesis, and whether the mitochondrial fusion and fission
machinery might represent attractive targets for therapeutic
intervention. He is interested collaborating and working with people
across the University, in both basic and clinical departments. [
more]
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Catalysts for Change
Marie-Louise Hammarskjold, MD, PhD and David Rekosh, PhD, are
molecular geneticists. For the last 20 years, the couple has
worked steadily and qquietly to unravel the genetic mysteries of HIV as
co-direcotrs of the Myles Thaler Center for AIDS and Human Retrovirus
Research at the University of Virginia. [...] -
More recently, as drug development, treatment and education
have helped stabilize the AIDS crisis int eh U.S., Hammarskjold and
Rekosh have turned some of their attention to the epidemic that is
still devastating other parts of the world. More specifically,
they've turned their attention to Africa.
Read more about the scientific work and outreach of the two
MIC faculty and Co-Directors of the Thaler Center http://catalog.e-digitaleditions.com/i/84132
pp.22-25
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Victor H. Engelhard, PhD wins SOM Team Science Award for his work
with the Melanoma Immunotherapy Group (other Team members: Craig
L. Slingluff, Jr., MD, FACS and Donald F. Hunt, PhD):
“This is is a group that you at UVa should be extremely proud to
have fostered. It is one that many institutional leaders can
only wish to have developed at their universities.” –
Colleague
“This is is a real ‘Dream Team’ that should be an exemplar for
future UVa research teams to emulate.” – Colleague
“Together, they have
created a world-recognized center for utilizing the immune system to
treat cancer which in turn has served as the
foundation for a Cancer Center Program that has consistently been among the most
highly regarded elements of the University of Virginia’s Cancer Center Support Grant from
NCI.” – Colleague [source: Award
Poster]
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Daniel G. Gioeli, PhD wins SOM Team Science
Award for his work with the Prostate Cancer Research
Group (other team members: Bryce M. Paschal, PhD, Anindya Dutta,
MBBS, PhD, Henry F. Frierson, Jr., MD, David Wotton, PhD, Mark R.
Conaway, PhD
“What better example of interdisciplinary collaborative
team science is there at UVa SOM? is team includes geneticists and
molecular and cell biologists working in concert with a biostatistician
and a pathologist on innovative animal models of human disease.” –
Colleague
“By virtue of [their Program Project] award we can be
assured that they have been judged by experts in the eld to be one of
the premier research teams in the country.” – Colleague
“is team brings together basic and clinical scientists
with complementary expertise, a track record of collaboration, and a
shared vision of dening mechanisms of prostate cancer progression. is
P01 project will have a major impact on the prostate cancer field….” –
Colleague [source: Award Poster]
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Loren Erickson, PhD wins SOM Dean's Award for Excellency in
Teaching
"He is patient and methodical, moving at the pace of the
student, adapting to their learning needs, and allowing the student to
ask questions, ensuring they fully understand the concept." -
Student
"His passion for science is infectious and it is his
unwavering enthusiasm that drives students not only to excel under his
tutelage but to give them the desire to learn more." - Student
“Dr. Erickson is one of the students’ favorites...in both
the old and the new curricula... The future of medicl education at our
institution is bright and our students will be better physicians
because of Dr. Erickson." - Colleague [source: Award Poster]
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Graduation 2012 - Congratulations to all graduates
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Farrow Fellowship for
postdoctoral application
Congratulations to Yulia Koryakina, Daniel G. Gioeli Lab, for
her Farrow Fellowship for postdoctoral application “The Effect of
Extracellular Matrix Rigidity on Prostate Cancer Cell Growth and
Androgen Receptor Transcriptional Program”, April 2012.
This proposal integrates two concepts important in prostate cancer
progression: steroid receptor signaling and extracellular matrix
rigidity.
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Poster Award at FASEB
Summer Conference
Brautigan Lab
member and Senior Scientist Dr. Lifu Wang, won one of the three poster
awards in July 2012 at the FASEB Summer Conference on Protein
Phosphatases.
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Christine Coquery (Erickson Lab) wins two awards
May 2012 - Gina Finzi Memorial Summer Fellowship ($4000) from
the Lupus Foundation of America [
more]
June 2012 - Student Travel Award ($950) from the Society for the
Advancement of Cytometry to attend the Cyto 2012 conference in Leipzig,
Germany
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Brittany Johnson, graduate student in the Criss
lab, was selected to give a talk at the American Society for
Microbiology 2012 annual meeting. The title of her talk
is Neisseria gonorrhoeae alters antimicrobial granule
mobilization and phagolysosome formation to survive intracellularly in
human neutrophils. She will be presenting during the session entitled
Phagocytes: Heroes and Victims of Infection. |
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2012 Women in Medicine Leadership
Award
The award is given annually to a faculty
member who demonstrates excellence in leadership, scholarship and
mentoring, and who exerts influence in fostering a better institutional
environment by advocating for women's issues.
Bouton has mentored numerous
undergraduate, medical and bioengineering students. She has a long
history of competing successfully for research awards from the National
Institutes of Health, and pre-doctoral and doctoral training awards
from the National Cancer Institute. [more]
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Outstanding MII Graduate Student
Shawn Fahl, a student in Tim Bender's laboratory, has been
chosen as the Outstanding MII graduate student. He will be the 2012
Peach/Hungerford Award Nominee for the MII/MIC Graduate Program. Shawn
will join the pool of other BIMS Graduate Programs' outstanding
students, in the next round of selection for the Peach and Hungerford
Awards, which will be announced during the GBS Symposium in April
2012.
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Recipient of the Robert R. Wagner Prize for Outstanding
Research in Microbiology
George Liechti, a student in Joanna
Goldberg's laboratory, has been chosen as the winner of the Robert R.
Wagner Prize for Outstanding Research in Microbiology. George will
receive the Wagner Award and present a seminar to the Department and
others in the SOM at a MIC seminar in May
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Best Presentation Award
Stacey Gorski, a student in Tom Braciale's lab, won best
presentation award for: "The biphasic role of IL-5 during influenza
infection." at the 2012 Robert J. Huskey Research
Exhibition
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Young Investigator Award, Best Poster Award and more...
Weiner Z.P., Cardani A., Glomski I.J. Seeding of Bacillus
anthracis into the draining lymph node by “Trojan horse” phagocytes
does not mediate subcutaneous infection lethality. Huskey Research
Symposium 2012, Charlottesville, VA, USA
Presenting student received a third- place poster award
Weiner Z.P., Cardani A., Glomski I.J. Seeding of Bacillus
anthracis into the draining lymph node by “Trojan horse” phagocytes
does not mediate subcutaneous infection lethality. University of
Virginia Infectious Disease Research Day 2012
Presenting student was winner of Best Poster Award
Weiner Z.P., Cardani A., Glomski I.J. Seeding of Bacillus
anthracis into the draining lymph node by “Trojan horse” phagocytes
does not mediate subcutaneous infection lethality. Bacillus- ACT
Meeting 2011. Bruges, Belgium
Presenting student was winner of the “Young Investigator Award”
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Lowe D.L., Ernst S.M., Glomski I.J. Characterizing in vivo
bottlenecks in disseminating inhalational anthrax. Huskey Research
Symposium 2012, Charlottesville, VA, USA
Presenting student received a second- place poster award
*Lowe D.L., Ernst S.M., Glomski I.J. Characterizing in vivo
bottlenecks in disseminating inhalational anthrax. University of
Virginia Infectious Disease Research Day 2012
Presenting student was winner of Best Presentation Award
Lowe D.L., Ernst S.M., Glomski I.J. Characterizing in vivo
bottlenecks in disseminating inhalational anthrax. Bacillus- ACT
Meeting 2011. Bruges, Belgium
Presenting student was the recipient of a travel award.
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2012 ASM Graduate Microbiology Teaching
Award
2012 ASM Graduate Microbiology Teaching
Award is Joanna B. Goldberg, Ph.D., Professor, Department of
Microbiology, Immunology, and Cancer Biology, University of Virginia,
and a Fellow of the American Academy of Microbiology.
"Goldberg is truly deserving of this
award," describes Sara Cassidy of the University of Michigan, a former
student of Goldberg's. "Through years of practice, she has developed an
uncanny ability to detect and address the needs of individual
students-a quality of mentorship that is difficult to teach."[
more]
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| MIC AWARDS - NEWS - EVENTS 2011 |
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June 2011
Microcosm
March 2011
Microcosm
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Alison Criss is among the five "Young
U.Va. Innovators" chosen for FEST Funding.
"U.Va. faculty members are annually invited to submit proposals for
FEST funding. This year, 17 researchers from across the scientific
disciplines presented a range of projects. A review committee made up
of senior faculty chose the winners based on originality and likeliness
of attracting significant future funding.
"In a field of extremely strong proposals, three young biomedical
researchers stood out as leaders in their respective fields," said
microbiology professor Marcia McDuffie, who served on the review
committee.
Criss garnered FEST funding for a project that will use
state-of-the-art techniques to define the mechanisms by which
pathogenic Neisseria bacteria evade clearance by the immune system,
generating devastating diseases such as gonorrhea. The methods she is
developing could lead to breakthroughs in understanding at the genome
level the resistance of gonorrhea – and other global infectious
diseases – to current antibiotics.
"Dr. Criss has established an internationally recognized research
program on the interactions between bacteria and the human immune
system," McDuffie noted."
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Graduation 2011: 17 of the 45 BIMS PhD graduates were from the
Department of Microbiology!
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Pictured to the right:
Madhura Lohia with mentor Ian Macara, Virginia Carroll (mentor Mike
Brown not
pictured), Jessica Pritchard and Kirsten Ludwig with mentor Sally
Parsons, Marcin Walkiewicz (mentor Dan Engel) Associate Dean of
Graduate and Medical
Programs Amy Bouton, and Michael Stadnisky (mentor Mike Brown).
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Read the Department of Microbiology newsletter.
Jan. 2011
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Chairman of the UVA School of Medicine’s Department of
Microbiology and director of the UVA Center for Cell
Clearance, Ravichandran is internationally recognized for his
ground-breaking research into the mechanisms of cell clearance. When
functioning properly, our bodies safely remove an estimated one million
dying cells per second. Failure to promptly remove dying cells,
however, is linked to chronic inflammation, developmental defects, and
such autoimmune diseases as lupus, arthritis and atherosclerosis. [
more]
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Matt Hufford, Thomas Brachiale Lab, wins the Wagner Prize for
outstanding graduate student research in Microbiology. He was also
selected to represent the MII program for the Peach/Hungerford
awards.
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Jay Fox, PhD, Professor and Assistant Dean of Research
Support of Microbiology
University of Virginia Medical School,
Charlottesville and his contributions to studies of snake
venom toxins have landed him on the pages of ASBMB today.
Read the full article:
http://www.asbmb.org/asbmbtoday/asbmbtoday_article.aspx?id=11118
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| MICROBIOLOGY AWARDS - NEWS - EVENTS 2010 |
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Read the Departmental Newsletters
Dec. 2010
Nov. 2010
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Marie Louise Hammarskjold, MD, PhD and David Rekosh, PhD,
Myles H. Thaler Center Awarded a new Patent and a Travel Award to teach
in South Africa.
The patent is for the discovery of a compound that inhibits
HIV replication. This work is and important step in the
development of an entirely new class of anit-HIV drugs.
The travel award will help fund a trip to the University of
Venda, South Africa, where members of the Thaler Center have already
taught students in previous years.
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UVa researchers breaking ground on male fertility (Daily
Progress, Dec. 25, 2010)
Kodi S. Ravichandran, chairman of the UVa
Department of Microbiology, and Jeffrey J. Lysiak, assistant professor of
urology, have spent four years studying how the male testes remove
dead or dying immature sperm cells. This removal is needed for testes
to remain healthy and normal, Lysiak said.[
excerpt from the Daily Progress article. Read
more]
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October 2010: Kodi S. Ravichandran, PhD, was announced to be the
new Chair of the Department of Microbiology. Dr. Ravichandran, the
Harrison Distinguished Professor of Microbiology, joined the department
in 1996 and was appointed Professor of Microbiology in 2004. He has
served as Director of the Center for Cell Clearance since 2008.
Dr. Ravichandran’s research focuses on apoptotic cell clearance and
intracellular signaling pathways regulating T and B lymphocyte
function. The daily clearance of billions of apoptotic (dead) cells is
fundamentally important in maintaining health. Failure to promptly and
efficiently clear apoptotic cells can lead to chronic inflammation,
autoimmunity and developmental defects. Dr. Ravichandran’s laboratory
addresses how the dying cells are recognized by phagocytes, ingested,
and removed without harm to the host. His laboratory is also addressing
how adapter proteins and chemokine receptors regulate specific
checkpoints during T cell development in the thymus.
After receiving a degree in Veterinary Medicine from Madras
Veterinary College, Dr. Ravichandran received his PhD in Molecular
and Cell Biology from the University of Massachusetts at Amherst in
1992. He performed his post-doctoral work in the Division of Pediatric
Oncology at the Dana-Farber Cancer Institute, Boston. After a year as
Instructor at Harvard Medical School, Dr. Ravichandran joined the
faculty at UVA.
Dr. Ravichandran has authored more than 90 articles in peer-reviewed
journals, including multiple publications in the top biomedical
journals such as Cell, Nature, Science, Nature Immunology and Nature
Cell Biology. Dr. Ravichandran’s laboratory has been highly
productive over the years here at UVA, including four articles
published in Nature in the past 12 months. He serves on many NIH
review panels and other granting agencies, and also serves as a
reviewer for numerous biomedical journals. He has been an Invited or
Plenary Speaker in many national and international meetings and is a
recognized world leader in the fields of apoptosis and cell
clearance.
Dr. Ravichandran has also distinguished himself with his leadership
in research and teaching at UVA. Dr. Ravichandran is the Program
Director of the Immunology T32 Training Grant and oversaw its
successful competitive renewal in 2010. He was also honored with the
Robert J. Kadner Mentoring Award for graduate and post-doctoral
training.
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David Brautigan, PhD, Professor of
Microbiology and
Director of the Center for Cell Signaling
has accepted the invitation to serve as chairperson of the
Molecular and Integrative Signal Transduction Study Section for
Scientific Review at the NIH. "Membership on a study section represents
a major commitment of professional time and energy as well as a unique
opportunity to contribute to the national biomedical research effort.
Members are selected on the basis of their demonstrated
competence and achievement in their scientific discipline as evidenced
by the quality of research accomplishments, publications in scientific
journals, and other significant scientific activities, achievements and
honors. Service on a study section also requires mature judgment and
objectivity as well as the ability to work effectively in a group. The
skill and leadership offered by the chairperson determine to a
significant extent the effectiveness and efficiency of the review
group." (excerpt from the letter by Toni Scarpa, MD, PhD, Director of
the Center for Scientific Review to inform Dean Dekosky, MD of the UVA
Medical School about David Brautigan's new responsibility.)
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Two Week Intensive Course and Lab Practicum at the University of
Venda, South Africa by the Myles H. Thaler AIDS Center and the
Microbiology Department
This spring, five members (Lou Hammarskjold,
David Rekosh, AJ Roberts, Lisa Nichols and Emily Sloan) of the Myles H.
Thaler AIDS Center and the Microbiology Department joined faculty and
students at the University of Venda (UNIVEN) in Limpopo Province, South
Africa, for a two-week intensive course and lab practicum emphasizing
the molecular biological roles of RNA. Professors Hammarskjold and
Rekosh lectured each morning to 30 students who are pursuing
undergraduate honors degrees or graduate degrees in microbiology,
biochemistry or zoology. Small group discussions, facilitated by UVA
and UNIVEN team members, followed each morning's lecture and helped
clarify critical concepts. For nearly half the students, the afternoons
were filled with an intensive lab practicum that emphasized PCR,
cloning, transformations and colony selection, sequence analysis and
bioinformatics, cell culture and transfections, fluorescent microscopy,
and bioluminescent assays. The course, lab practicum, and other team
activities were a critical part of capacity building at UNIVEN for
Professors Pascal Bessong and Samie Amidou, UNIVEN researchers, who
have ongoing collaborations with UVA faculty in Microbiology and the
Center for Global Health. Professors Hammarskjold and Rekosh plan to
return in the spring of 2011 to lecture in a microbiology course that
is directed by Professor Amidou .
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May 28, 2010 - University of Virginia medical professor Dr.
Thomas Platts-Mills has been elected a Fellow of the Royal Society for
his research into the causes of asthma and allergic disease. The Royal
Society is the United Kingdom's national academy of science and the
oldest scientific academy in the world. His recent work, published in
the New England Journal of Medicine in 2008, looked at patients who
developed a life-threatening allergic reaction, called anaphylaxis,
during treatment for cancer. In February 2009, he led a study on
anaphylactic reactions that occurred several hours after eating beef,
pork or lamb. Both of these discoveries are related to IgE antibodies
to a complex mammalian sugar that appear to be induced by tick bites.
This represents a paradigm shift in the understanding of allergic
reactions, including those to food. [more]
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source: Finals Weekend 2010 |
Congratulations to all MII graduates 2010! |
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Christopher Burns, PhD Associate Professor of Medical Education
has been selected for the 2009-2010 "Excellence in Graduate Mentoring
Award" by the graduate students of the Florida Atlantic University
College of Biomedical Science for the second year in a row. |
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Appointment of Amy H. Bouton, PhD, to the position of Associate Dean
for Graduate and Medical Scientist Programs, effective July 1,
2010.
Dr. Bouton, who has been at UVA since 1991, is Professor of
Microbiology. Her lab has two major research interests - adhesion
signaling in macrophages, and molecular mechanisms by which breast
cancer cells become resistant to the growth-inhibitory effects of
antiestrogens (competitive inhibitors of the estrogen receptor).
In her role as Associate Dean for Graduate and Medical Scientist
Programs, Dr. Bouton will be responsible for overseeing and supporting
all aspects of graduate studies at the School of Medicine. This
includes oversight of the BIMS programs, the Graduate Programs Office,
and coordination of graduate studies across departments and schools
within the University.
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2010 Robert R. Wagner Prize for Outstanding Research in
Microbiology for Derek Dube, a student in Judy White's
laboratory
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2010 Peach/Hungerford Award Nominee selected for
the MII Graduate Program: Stacy Park, a student in Borna
Mehrad's laboratory.
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Congratulations to Amelia Hufford (Ravichandran Lab) for
her selection by the Scientific Review Panel of the Lindau Council to
be a participant of the 60th Interdisciplinary Meeting of Nobel
Laureates. Amelia was selected in a nationwide competition to
attend the meeting from June 27 to July 2, 2010, at Lindau
(Germany).
Amelia is the sole representative for the University of
Virginia!
More information on the meeting is available at http://www.orau.org/lindau/.
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Mike Stadnisky, a student in Mike Brown's
laboratory, has been selected for the Award
for Excellence in Scholarship in the Sciences & Engineering.
This award recognizes excellence in original scholarship by Ph.D.
students at the University. In addition, it rewards those students
bringing recognition to graduate programs at U.Va. through their
intellect, dedication, creativity, and passion. This year's competition
was very strong!
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| MICROBIOLOGY AWARDS - NEWS - EVENTS 2009 |
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The University of Virginia presented two Thomas Jefferson Awards on
October 16, 2009, one recognizing excellence in service and the other
recognizing excellence in scholarship. They are the highest honors that
the University bestows.The 2009 Jefferon award for scholarship went to
J. Thomas Parsons, chairman of the Department of Microbiology and F.
Palmer Weber Professor of Medical Research. Parsons, who joined the
School of Medicine faculty in 1974, is widely recognized as a leading
researcher in the field of cell signaling, an important avenue of
cancer research.
"Tom is among the top couple percent in total citations among
biochemists and cell biologists," he wrote. "Many researchers at U.Va.
and around the world owe their careers to FAK and Tom's discovery."
(Rick Horwitz, PhD)
[read the Complete
News Release]
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Sept 09:
Academy of Distinguished Educators
Amy H. Bouton, PhD, Professor of Microbiology receives the Robert J. Kadner Award for Outstanding Graduate
Student Teaching
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NIH, Center for Cancer Research
Laboratory of Molecular Biology
Head, Biochemical Genetics Section
Laboratory Co-Chief
Beyond Transcription: Regulatory Networks with Small RNA
Regulators
9/22/2009
Jordan Hall Conference Center
Auditorium
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Two Distinguished Scientist Awards to Professors of Microbiology
J.T. Parsons', PhD and M. Weber's, PhD leadership in their research
is recognized both at UVa and by peers nationally and internationally
as having made a major impact on their field of study:
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J.T. Parsons, PhD Professor of Microbiology and Chair,
receives the 2009 University of Virginia Distinguished
Scientist Award for his research contributions to Rous sarcoma
virus mediated transformation (viral mediated cancer), identification
of tyrosine phosphorylated substrates by the Src gene using monoclonal
antibodies, identification of several important, novel proteins,
especially focal adhesion kinase (FAK), solidified the emerging notion
that adhesion receptors mediate signaling and linked FAK-mediated
signaling to proliferation, programmed cell death, gene expression,
migration and synaptic function in normal cells and implicated it in
many diseases, particularly cancer, leading to drugs now in human
trials against metastatic cancer that inhibit the kinase activity of
FAK.
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M. Weber, PhD, Director, Cancer Center, receives the 2009
University of Virginia Distinguished Scientist Award for his
research contributions. His early research on the Src oncogene
established the importance of multiple tyrosine phosphorylations in
causing malignant cell behavior. Further research has profoundly
influenced cell regulation research not only in cancer, but in
inflammation, diabetes, infectious diseases, and normal development.
Weber also was the first to identify a mammalian scaffold protein for
MAP Kinases, which regulates and channels the signals. The use of the
phosphospecific antibodies revealed that MAP Kinase activation
characterized the progression of prostate cancer to hormone
independence, opening up new therapeutic possibilities in that disease.
In more recent years, his research has become more oriented toward
translational goals, and Weber has developed new ways of looking for
combinatorial therapies for a variety of cancers, including prostate,
melanoma, bladder and head and neck cancers, each of which provides
unique opportunities to match knowledge about signaling with potential
therapeutic interventions.
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Microbiology Faculty Deborah Lannigan, Ian Macara, J.Thomas
Parsons and Vic Engelhard Featured in the UVA Alumni
Magazine:
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Different Skills, Common Goal
Teamwork yielding results in cancer research
Text and Images from UVA Magazine
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TARGET: BREAST CANCER
Team: Deborah Lannigan (cell and molecular biologist), Ian Macara
(cell biologist), David Brenin (surgeon)
Research: They are growing "organoids" from human tissue to track
cancer growth at the cellular level and synthesizing a compound derived
from the Amazon jungle plant Fosteronica Refracta to stop the growth of
breast cancer cells.
In layman's terms: U.Va. is pioneering a process to "grow" live,
healthy breast tissue in the lab. By adding cancer cells to the tissue,
they can see how cancer develops in human tissue rather than in mice.
This breakthrough will be used to test the effectiveness of several
therapies, including a compound discovered at U.Va. that inhibits the
growth of breast cancer cells without harming healthy cells.
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TARGET: PANCREATIC CANCER
Team: Kim Kelly (biomedical engineer), J. Thomas Parsons (cancer
biologist), Todd Bauer (surgeon-scientist)
Research: They are exploring the basic biology of pancreatic cancer,
including identifying a protein (uPAR) that, when blocked, decreases
the growth and metastasis of human pancreatic cancers in mice. They are
evaluating signaling pathways in individual tumors to develop
patient-specific targeted therapies and identifying early biomarkers
that could make precancerous cells visible via MRI and PET scans.
In layman's terms: The five-year survival rate for pancreatic cancer
patients is only 5 percent. Diagnosing pancreatic cancer early,
preventing its spread and understanding the genetic profile of each
patient's individual tumor can greatly improve treatment options and
outcomes.
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TARGET: DEVELOPING CANCER VACCINES
Team: Craig Slingluff (surgeon-scientist), Don Hunt (chemist), Vic
Engelhard (microbiologist and immunologist)
Research: The group has pioneered the development of vaccines that
fight melanoma and other cancers. They were the first group to identify
a peptide antigen in melanoma that can be targeted by T-lymphocytes,
the cells capable of directly killing cancer cells.
In layman's terms: By identifying molecular targets on cancer cells,
the team can use vaccines to muster the body's immune system in a
"nontoxic war on cancer." Result: killing cancer cells without killing
healthy tissue. Since 1996, the Human Immune Therapy Center has
enrolled more than 500 patients in anti-cancer vaccine clinical
trials.
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Nicholas Sherman, PhD receives award for Thermo Electron
Orbitrap XL & ETD Mass Spectrometer
The new instrument will be the foundation of high resolution/mass
accuracy HRMA) experiments in complex immunoprecipitations (IPs),
biomarkers and
post-translational modifications (PTMs) - allowing for more complex
and in-depth experiments to be performed at UVA.
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""The Art of Diagnosis" is a project still in its "embryogenesis
stage," according to Ragan and Turner. In March, they held a public
talk to explain the concept and brainstorm about research possibilities
with the audience, which included art therapists, neuroscientists,
infectious disease specialists and community members simply piqued by
the hypothesis." Find out more
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Sandy Weirich, graduate program coordinator in the Department of
Microbiology, was named Employee of the Month for January 2009.
As one nominator wrote: "She is simply a wonderful person who is an
absolute joy to work with. In short, Sandy represents the ideal
employee - one who is fully skilled, motivated, hard working, and
enjoys what they do."
Department Chair Tom Parsons says they could not function without
her.
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2009 Peach Hungerford Award Recipient
Karin Eisinger is the MII's 2009 recipient for the Peach/Hungerford
Award. Karin is a student in Deb Lannigan's laboratory in the Center
for Cell Signaling. Karin was chosen by a selection committee comprised
of six MII and Microbiology faculty members and chaired by David
Benjamin, Professor Emeritus of Microbiology. Congratulations to Karin
as this year's recipient.
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2009 Wagner Prize
The 7th annual Robert R. Wagner Prize for Outstanding Research in
Microbiology was awarded to Anna Maria Copeland. Anna Maria is a
doctoral Student in Dr. Jay Browns's lab. Congratulations, Anna
Maria!
Find more details on the Wagner Awards web site.
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MICROBIOLOGY AWARDS - NEWS - EVENTS 2008
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Dan Gioeli, Ph.D. gets Grant for
Prostate Cancer Research from the National Cancer
Institute
"For me the most exciting thing is now we have some of the resources
to address what I think is a very interesting and important
question.[...] now we can start to answer a piece of the
puzzle."
Daniel Gioli, Ph.D."
read excerpt from news show on NBC29
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Microbiology Retreat October 14, 8am-6pm
Stonefire Station, Barboursville
(click on image to see complete group picture) |
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Sept 08:
Academy of Distinguished Educators
Victor H. Engelhard (Robert J. Kadner Award for Outstanding Graduate
Student Teaching)
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2008 Gina Finzi Summer Fellowship
Award from the Lupus
Foundation of America
Chao Jiang in Dr. Loren
Erickson's lab
The purpose of this award is to
foster an interest among young researchers in systemic lupus
erythematosus (SLE) through support of basic, clinical, or psychosocial
research under the supervision of an established
investigator.
Project:"The Role of BCMA for Plasma Cell Survival in
Murine SLE".
Mentor: Dr. Loren
Erickson
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Dr. John Roth with Kadner Family and Dr. J.Thomas Parsons after the
lecture. |
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John Roth, Ph.D.
Distinguished Professor
College of Biological Sciences
UC Davis
"Origins of Mutations under
Selection"
September 22, 2008
12:30pm
Jordan Hall Conference Center Auditorium
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The Robert Bennett Bean Award: Established by the Class of 1966 in honor of Dr.
Robert Bennett Bean, anatomist, anthropologist, and chair of the
Department of Anatomy from 1916 to 1942. This yearly award is
presented by the second year class to one member of the faculty for
excellence in teaching the basic medical sciences.
Julie Davis Turner, PhD
Professor Turner received this award for the
second year in a row.
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2008 Biomedical Sciences
Outstanding Graduate Student Award
Michelle Lynn Demory in Dr.
Sarah Parsons' Lab |

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Eighth Annual Robert J. Huskey
Graduate Research Exhibition - first place for oral
presentation:
Anna Maria Copeland in Dr. Jay
Brown's lab
"Herpes simplex virus replication:
Roles of viral proteins and nucleoporins in capsid-nucleus
attachment"
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Eighth Annual Robert J. Huskey
Graduate Research Exhibition - first place for oral
presentation:
Katie Hulse in Dr. Judith Woodfolk's lab
"Targeting Fel d 1 to FcgammaRI: Single Cell Analysis reveals a novel
variation of the Th2 response in cat-allergic
subjects."
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Graduate Biosciences Society Student
Symposium - second place for poster presentation
Colin Brinkman in Dr. Victor
Engelhard's lab
"Activated CD8 T cells Redistribute to Antigen Free Lymph Nodes and
Exhibit Effector and Memory Cell Characteristics"
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2008 Jill E. Hungerford
Award
Daeho Park in Dr. Kodi Ravichandran's lab
Thesis Project: BAI1 is an Engulfment Receptor for Apoptotic Cells
Upstream of ELMO1/Dock180/Rac Signal Module
Mentor: Dr. Kodi Ravichandran |
pic. not available
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2008 Michael J. Peach Award
Edward Stites in Dr. Kodi
Ravichandran's lab
Project: Theoretical and Experimental Analysis of Oncogenic Ras
Signaling
Mentor: Dr. Kodi
Ravichandran
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AACR-AstraZeneca Scholar-in-Training
Award
Sergio Sanchez in Dr. Sarah J. Parsons' lab has been selected
to receive this award to support his attendance to the AACR
Annual Meeting 2008 in San Diego, CA, USA, April 12th - 16th,
2008.
"AstraZeneca has graciously donated funds to the AACR to support young
investigators who will be presenting meritorious proffered papers. With
Scholar-in-Training Awards presented to fewer than 10% of applicants,
overall the process is highly competitive. Congratulations on being
selected!" |
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Deborah Lannigan, PhD in the news |
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Microbiology and Global Health
Lecture
"Polio Eradication: A Global
Case Study"
Neal Nathanson, M.D.
Associate Dean
Global Health Programs
University of Pennsylvania
School of Medicine
J. Thomas Parsons, PhD, Dick Guerrant,
PhD, Becca Dillingham, PhD and Neal Nathanson, PhD
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Glomski Lab Warming: Ian Glomski
joined the Microbiology faculty in August 2007.
Ian J. Glomski
Degree(s): Ph.D.
Graduate School: University of California, Berkeley
Primary Appointment: Assistant Professor of Microbiology
Research Interests:
Elucidating the molecular mechanisms of B. anthracis pathogenesis;
detection and prevention of anthrax.
Email Address: ijg2b@virginia.edu
Ian Glomski, PhD and Ann Beyer, PhD at the lab warming
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2008 Wagner Prize
The 6th annual Robert R. Wagner Prize for
Outstanding Research in Microbiology was awarded to Michelle L. Demory,
Ph.D. Michelle is in Dr. Sarah J. Parsons' lab.
Congratulations, Michelle!
Find more details on the Wagner Awards web site.
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Ian Macara, PhD receives Distinguished
Scientist Award
"Macara is recognized as a scientific
leader, both at U.Va. and beyond. He has been instrumental in acquiring
state-of-the-art cellular imaging equipment for the Advanced Microscopy
Facility, creating an invaluable resource for U.Va.'s scientists. In
addition, he has over 165 publications, many of which appear in
prestigious journals such as Cell, Science, and Nature. His citation
index of 58 is extremely high, indicating the importance and regard his
research has generated."
"Ian Macara's research on nuclear protein
transport and cellular polarity has shown how cells such as neurons or
mammary cells organize information to form specific structures, and to
orient within tissues," said Dr. Sharon L. Hostler, interim vice
president and dean of the School of Medicine. "This has significant
impact in understanding tissue development, and dysregulation of cell
function in early tumor progression."
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In 2007: |
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Dec. 07:
Microbiology/Global Health Seminar:
Dr. Tiffany Hamm, PhD
Director for HIV/AIDS Prevention, Care
and Treatment Program, Division of Retrovirology - US Military Research
Program, Walter Reed Army Institute for Research
"Supporting HIV Care and Treatment
in Kenya, Nigeria, Tanzania and Uganda"
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Oct 07:
Microbiology/Global Health Seminar:
Dr. Siddhartha
Mahanty, M.D., M.P.H.
Staff Physician
Helminth Immunology Section
Laboratory of Parasitic Disease NIAID, NIH
"Translational research in the
developing world: Collaborative studies on malaria and helminth
infections in West Africa"
Inaugural
Global Health Seminar with Dick Guerrant, Siddhartha Ma, and Tom
Parsons (10-17-2007)
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Sept
07:
Academy of
Distinguished Educators Distinguished Educators,
Robert J. Kader Award for Outstanding Graduate Teaching
:
Kodi S. "Ravi"
Ravichandran (Robert J. Kadner Award for outstanding graduate student
teaching) and J. Thomas Parsons (Chair).
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Thomas J.
Silhavy, Ph.D.
Warner-Lambert Parke-Davis Professor of Molecular Biology,
Princeton University
"Outer
Membrane Biogenesis in Gram-Negative Bacteria"
Monday,
September 17, 2007 at 4pm
Jordan Hall Conference Center Auditorium
Reception to follow
For any information please contact Lynn McCutcheon.
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Congratulations to the following MII
students:
Anna Maria Copeland, Ph.D. candidate,
in Dr. Jay Brown's lab has received a Ruth L. Kirschstein
National Research Service Award (NRSA) for Individual Predoctoral
Fellows through the National Institute of Neurological Disorders
and Stroke (NINDS);
Rebecca Obeng, MSTP student, in Dr. Vic Engelhard's lab
has received a Ruth L. Kirschstein National Research Service
Award (NRSA) from the National Cancer Institute with up to a 5 year
renewal.
Teresa Bernaciak, Ph.D. candidate, in Dr. Corinne Silva's lab
received funding on a DOD Breast Cancer Research proposal with up to a
3 year renewal for the research on "Role of STAT5b in Breast Cancer
Progression and Metastasis." |
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In 2006:
Martha W.
Campbell Retires
Read about Martha W. Campbell's achievements in the department and
look at pictures of the retirement party.
2006 Wagner Prize Awarded
The 4th annual Robert R. Wagner Prize for Outstanding Research in
Microbiology was awarded to Michael W. Cruise on March 29,
2006. Michael is in Dr. Young Hahn's lab.
Congratulations, Michael!
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2006
Kadner Symposium :
The first annual Kadner Symposium took place on September 12, 2006
in honor and memory of:
Robert J. Kadner, Ph.D.
We mourn the loss of our friend and collegue Robert J. Kadner,
Ph.D. Professor and Vice Chair of Microbiology. Read the
obituary.
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